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Long noncoding RNA TMPO-AS1 accelerates glycolysis by regulating the miR-1270/PKM2 axis in colorectal cancer

Authors: Yingmin Jin, Aimin Jiang, Liying Sun, Yue Lu

Journal: BMC Cancer

PubMed ID: 38383342

Doi: 10.1186/s12885-024-11964-w

Products & Services: Catalog Peptides

CD46 and CD59 inhibitors enhance complement-dependent cytotoxicity of anti-CD38 monoclonal antibodies daratumumab and isatuximab in multiple myeloma and other B-cell malignancy cells

Authors: Hongjie Wang, Theo Koob, Jonathan R Fromm, Ajay Gopal, Darrick Carter, André Lieber

Journal: Cancer Biol Ther

PubMed ID: 38361357

Doi: 10.1080/15384047.2024.2314322

Products & Services: Protein and Antibody Isolation

Discovery and Characterization of Selective, First-in-Class Inhibitors of Citron Kinase

Authors: Joshua J Maw, Jesse A Coker, Tarun Arya, Christopher M Goins, Dhiraj Sonawane, Sang Hoon Han, Matthew G Rees, Melissa M Ronan, Jennifer A Roth, Nancy S Wang, Hannelore V Heemers, Jonathan D Macdonald, Shaun R Stauffer

Journal: J Med Chem

PubMed ID: 38330278

Doi: 10.1021/acs.jmedchem.3c01807

Products & Services: Custom Vector Construction

Dissecting a two-domain alginate lyase of family PL6 reveals a mechanistic basis for substrate specificity and enzyme activity

Authors: Mikkel Madsen; Mette E. R nne; Agnes B. Petersen; Tobias Tandrup; Bo Pilgaard; Jesper Holck; Finn L. Aachmann; Casper Wilkens; Leesa J. Klau; Birte Svensson

Journal: The Journal of Biological Chemistry

PubMed ID: 41638429

Doi: 10.1016/j.jbc.2026.111227

Dissecting a two-domain alginate lyase of family PL6 reveals a mechanistic basis for substrate specificity and enzyme activity

Authors: Mikkel Madsen; Mette E. R nne; Agnes B. Petersen; Tobias Tandrup; Bo Pilgaard; Jesper Holck; Finn L. Aachmann; Casper Wilkens; Leesa J. Klau; Birte Svensson

Journal: The Journal of Biological Chemistry

PubMed ID: 41638429

Doi: 10.1016/j.jbc.2026.111227

The B. subtilis replicative polymerases bind the sliding clamp with different strengths to tune replication processivity and fidelity

Authors: Luke G. O Neal; Madeline N. Drucker; Ngoc Khanh Lai; Ashley F. Clemente; Alyssa P. Campbell; Lindsey E. Way; Sinwoo Hong; Emily E. Holmes; Sarah J. Rancic; Nicholas Sawyer; Xindan Wang; Elizabeth S. Thrall

Journal: biorxiv

PubMed ID: 40161823

Doi: 10.1101/2025.03.10.642433

An Antioxidative and Active Shrinkage Hydrogel Integratedly Promotes Re-Epithelization and Skin Constriction for Enhancing Wound Closure

Authors: Jiacheng Sun, Wang Jia, Hedong Qi, Jiawei Huo, Xiaodan Liao, Yuan Xu, Jun Wang, Zihao Sun, Yang Liu, Jingchao Liu, Mingming Zhen, Chunru Wang, Chunli Bai

Journal: Adv Mater

PubMed ID: 38332741

Doi: 10.1002/adma.202312440

Products & Services: Protein and Antibody Isolation

Immune evasion, infectivity, and fusogenicity of SARS-CoV-2 BA. 2.86 and FLip variants

Authors: Panke Qu 1, Kai Xu 1, Julia N Faraone 2, Negin Goodarzi 1, Yi-Min Zheng 1, Claire Carlin 3, Joseph S Bednash 4, Jeffrey C Horowitz 4, Rama K Mallampalli 4, Linda J Saif 5, Eugene M Oltz 6, Daniel Jones 7, Richard J Gumina 8, Shan-Lu Liu

Journal: Cell

PubMed ID: 38194968

Doi: 10.1016/j.cell.2023.12.026

Products & Services: PCR Cloning and Subcloning

A Cancer Nanovaccine for Co-Delivery of Peptide Neoantigens and Optimized Combinations of STING and TLR4 Agonists

Authors: Jessalyn J. Baljon, Alexander J. Kwiatkowski, Hayden M. Pagendarm, Payton T. Stone, Amrendra Kumar, Vijaya Bharti, Jacob A. Schulman, Kyle W. Becker, Eric W. Roth, Plamen P. Christov, Sebastian Joyce, and John T. Wilson*

Journal: ACS Nano

PubMed ID: 38386282

Doi: 10.1021/acsnano.3c04471

Products & Services: Peptide Synthesis

A Gamma-adapted subunit vaccine induces broadly neutralizing antibodies against SARS-CoV-2 variants and protects mice from infection

Authors: Lorena M Coria , Juan Manuel Rodriguez , Agostina Demaria , Laura A Bruno , Mayra Rios Medrano , Celeste Pueblas Castro , Eliana F Castro , Sabrina A Del Priore , Andres C Hernando Insua , Ingrid G Kaufmann , Lucas M Saposnik , William B Stone , Lineia Prado , Ulises S Notaro , Ayelen N Amweg , Pablo U Diaz , Martin Avaro , Hugo Ortega , Ana Ceballos , Valeria Krum , Francisco M Zurvarra , Johanna E Sidabra , Ignacio Drehe , Jonathan A Baqué , Mariana Li Causi , Analia V De Nichilo , Cristian J Payes , Teresa Southard , Julio C Vega , Albert J Auguste , Diego E Álvarez , Juan M Flo , Karina A Pasquevich , Juliana Cassataro

Journal: Nat Commun

PubMed ID: 38307851

Doi: 10.1038/s41467-024-45180-8

Products & Services: Codon Optimization