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Discovery of FoTO1 and Taxol genes enables biosynthesis of baccatin III

Authors: Conor James McClune, Jack Chun-Ting Liu, Chloe Wick, Ricardo De La Peña, Bernd Markus Lange, Polly M Fordyce, Elizabeth S Sattely

Journal: Nature

PubMed ID: 40500440

Doi: 10.1038/s41586-025-09090-z

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Multiple intramolecular triggers converge to preferential G protein coupling in the CB2R

Authors: Adrian Morales-Pastor, Tamara Miljuš, Miguel Dieguez-Eceolaza, Tomasz Maciej Stępniewski, Vicente Ledesma-Martin, Franziska M Heydenreich, Tilman Flock, Bianca Plouffe, Christian Le Gouill, Jean Duchaine, David A Sykes, Colin Nicholson, Eline J Koers, Wolfgang Guba, Arne C Rufer, Uwe Grether, Michel Bouvier, Dmitry B Veprintsev, Jana Selent

Journal: Nature Communications

PubMed ID: 40500255

Doi: 10.1038/s41467-025-60003-0.

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mRNA-LNP vaccines against hepatitis B virus induce protective immune responses in preventive and chronic mouse challenge models

Authors: María José Limeres, Rocio Gambaro, Malin Svensson, Silvia Fraude-El Ghazi, Leah Pretsch, Daniel Frank, German A Islan, Ignacio Rivero Berti, Matthias Bros, Ying K Tam, Hiromi Muramatsu, Norbert Pardi, Stephan Gehring, Maximiliano L Cacicedo

Journal: Molecular Therapy

PubMed ID: 40518670

Doi: 10.1016/j.ymthe.2025.06.027

ELD1 mediates photoperiodic flowering via OsCCA1 alternative splicing and interacts with phytochrome signaling in rice

Authors: Liang Cai, Benyuan Hao, Zhuang Xu, Song Cui, Qianyun Wu, Jiyoung Lee, Haigang Hou, Yuan Hu, Liang Zhu, Jie Wang, Wen Li, Kongyou Chang, Weihao Shao, Shanshan Zhu, Xiangchao Gan, Chao Li, Ling Jiang, Yunlu Tian, Xi Liu, Shijia Liu, Liangming Chen, Haiyang Wang, Shirong Zhou, Jianmin Wan

Journal: Nature Communications

PubMed ID: 40537466

Doi: 10.1038/s41467-025-60839-6

Products & Services: Protein Electrophoresis and Western

Herpes simplex virus type 1 reshapes host chromatin architecture via transcription machinery hijacking

Authors: Esther González-Almela, Alvaro Castells-Garcia, François Le Dily, Manuel Fernández Merino, Davide Carnevali, Pol Cusco, Luciano Di Croce, Maria Pia Cosma

Journal: Nature Communications

PubMed ID: 40537528

Doi: 10.1038/s41467-025-60534-6

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Large-scale experimental assessment of variant effects on the structure and function of the citrate transporter SLC13A5

Authors: Wen-An Wang, Evandro Ferrada, Christoph Klimek, Tanja Osthushenrich, Aidan MacNamara, Tabea Wiedmer, Giulio Superti-Furga

Journal: SCIENCE ADVANCES

PubMed ID: 40577459

Doi: 10.1126/sciadv.adx3011

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Structural Insights into the Assembly of the African Swine Fever Virus Inner Capsid

Authors: Haining Li , Qi Liu , Luyuan Shao , Ye Xiang

Journal: Journal of Virology

PubMed ID: 37191520

Doi: 10.1128/jvi.00268-23

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Enhancement of CRISPR-Cas12a system through universal circular RNA design

Authors: Jiaqi Wang, Wei Zhang, Wentao Li, Qinyuan Xie, Ziyu Zang, Chaoxing Liu

Journal: Cell Reports Methods

PubMed ID: 40527291

Doi: 10.1016/j.crmeth.2025.101076

Products & Services: Molecular Biology Reagents

YAP maintains the dynamics of TDP-43 condensates and antagonizes TDP-43 pathological aggregates

Authors: Jiaqi Zhang, Jiaojiao Hu, Ruogu Liu, Tian Zhou, Xuewei Luo, Peigang Liang, Zaichao Xie, Qinyue Zhao, Yan Chen, Dan Du, Cong Liu, Yiming Zheng, Dan Li, Bo Wang

Journal: Nature Cell Biology

PubMed ID: 40542195

Doi: doi.org/10.1038/s41556-025-01685-y

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RIG-I-Inducing Small Molecules Potently Inhibit HMA-Resistant AML Through Igniting the Overloaded dsRNA Arsenal

Authors: Xueqin Chen 1, Jiaqi Wu 1, Yuntong Li 1, Jiayu Huang 1, Xiangqin Weng 1, Jiale Wu 1, Shujun Xiao 1 2, Huaxin Song 1, Zhengyuan Wang 1, Ni Yan 1, Fangfang Shi 1, Derun Zheng 1 2, Kai Tan 1 2, Hesong Zhang 1, Jingyi Cui 1 2, Wen Wu 1, Wei Wu 3, Sujiang Zhang 1, Min Lu 1

Journal: Advanced Science

PubMed ID: 40568903

Doi: 10.1002/advs.202414477

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