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Discovery of novel pyrrolidine-2,5-dione scaffold PICK1 PDZ inhibitors as anti-ischemic stroke agents

Authors: Yichen Jiang, Qi Liu, Ting Zhu, Ruiguo Liang, Yujiao Qin, Xiya Guo, Jiacheng Wang, Ping Li, Jie Zhou, Han Ju, Mingxin Dong

Journal: European Journal of Medicinal Chemistry

PubMed ID: 41386205

Doi: 10.1016/j.ejmech.2025.118410

Products & Services: Plasmid DNA Preparation

Native cell niche-inspired multiorder nanoassemblies orchestrate integrated interaction networks to guide muscle regeneration

Authors: Peng Lou, Yizhuo Wang, Yimeng Zhang, Xiyue Zhou, Lan Li, Shuyun Liu, Meihua Wan, Yanrong Lu, Jingping Liu

Journal: Molecular therapy: the journal of the American Society of Gene Therapy

PubMed ID: 41445187

Doi: 10.1016/j.ymthe.2025.12.044

Products & Services: Catalog IVT RNA products Custom mRNA synthesis

The Artemisia argyi oil reduces high-fat diet-induced obesity by enhancing thermogenesis in brown adipose tissue

Authors: Shuai Wang, ShengLan Lin, Fuan Xie, Shuting Liu, Ting He, Kun Chen, Zhengrong Huang, Wenlong Xie, Hongqiu Cheng, Jian Zhang, Weihua Li

Journal: NPJ science of food

PubMed ID: 41390517

Doi: 10.1038/s41538-025-00633-2

Products & Services: Molecular Biology Reagents Catalog Antibodies

The extracellular domain of mGluR6 regulates targeting to the conventional secretion pathway

Authors: Andrew P Rideout, Omar W Abuelatta, Melina A Agosto

Journal: Molecular and cellular neurosciences

PubMed ID: 41448371

Doi: 10.1016/j.mcn.2025.104068

Products & Services: Protein and Antibody Isolation

Semisynthetic, Multicolor Probes for Bioluminescence Imaging

Authors: Suong Tran, Kat Usavage, Lila P Halbers, Claire Choplick, Grace Helton, Brenden Young, Jennifer A Prescher, Colin M Rathbun

Journal: ACS Omega

PubMed ID: 41427193

Doi: 10.1021.5c07587

Products & Services: Peptide Synthesis

Mutational analysis of Yih1 and IMPACT reveals amino acids required for Gcn2 inhibition

Authors: Bianca J M Sansom, Victoria J Gibbs, Anja H Schiemann, Evelyn Sattlegger

Journal: FEBS Letters

PubMed ID: 40862493

Doi: 10.1002/1873-3468.70148

Products & Services: Plasmid DNA Preparation

Going Retro, Going Viral: Experiences and Lessons in Drug Discovery from COVID-19

Authors: Bing Wang; Dmitri Svetlov; Dylan Bartikofsky; Christiane E. Wobus; Irina Artsimovitch

Journal: Molecules

PubMed ID: 35744940

Doi: 10.3390/molecules27123815

Going Retro, Going Viral: Experiences and Lessons in Drug Discovery from COVID-19

Authors: Bing Wang; Dmitri Svetlov; Dylan Bartikofsky; Christiane E. Wobus; Irina Artsimovitch

Journal: Molecules

PubMed ID: 35744940

Doi: 10.3390/molecules27123815

Going Retro, Going Viral: Experiences and Lessons in Drug Discovery from COVID-19

Authors: Bing Wang; Dmitri Svetlov; Dylan Bartikofsky; Christiane E. Wobus; Irina Artsimovitch

Journal: Molecules

PubMed ID: 35744940

Doi: 10.3390/molecules27123815

First inhibitor of a bacterial two-partner secretion system

Authors: Alfred Hartojo; Laurence Don Wai Luu; Lachlan Adamson; Kyra Majors; Ashleigh S. Paparella; Peggy A. Cotter; Richard M. Johnson; Matthew Thomas Doyle

Journal: biorxiv

PubMed ID: 41648283

Doi: 10.64898/2026.01.11.698920