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Structural basis of SIRT7 nucleosome engagement and substrate specificity
Authors: Carlos Moreno-Yruela, Babatunde E Ekundayo, Polina N Foteva, Dongchun Ni, Esther Calvino-Sanles, Henning Stahlberg, Beat Fierz
Journal: Nature Communications
PubMed ID: 39900593
Doi: 10.1038/s41467-025-56529-y
Products & Services: Protein Electrophoresis and Western   
Synthetic lethality of mRNA quality control complexes in cancer
Authors: Vivian Prindle, Adam E Richardson, Kimberly R Sher, Sarah Kongpachith, Kaitlin Kentala, Sakina Petiwala, Dong Cheng, Deborah Widomski, Phuong Le, Maricel Torrent, Anlu Chen, Stephen Walker, Marianne B Palczewski, Diya Mitra, Vlasios Manaves, Xu Shi, Charles Lu, Stephanie Sandoval, Zoltan Dezso, F Gregory Buchanan, Daniel Verduzco, Brian Bierie, Jonathan A Meulbroek, William N Pappano, Joshua P Plotnik
Journal: Nature
PubMed ID: 39910291
Doi: 10.1038/s41586-024-08398-6
Products & Services: Custom Vector Construction   
Antibody prophylaxis may mask subclinical SIV infections in macaques
Authors: Christopher A Gonelli, Hannah A D King, SungYoul Ko, Christine M Fennessey, Nami Iwamoto, Rosemarie D Mason, Ashley Heimann, Dillon R Flebbe, John-Paul Todd, Kathryn E Foulds, Brandon F Keele, Jeffrey D Lifson, Richard A Koup, Mario Roederer.
Journal: Nature
PubMed ID: 39910294
Doi: 10.1038/s41586-024-08500-y
Products & Services: Gene Synthesis   
Structural basis of inhibition of human NaV1.8 by the tarantula venom peptide Protoxin-I
Authors: Bryan Neumann, Stephen McCarthy, Shane Gonen
Journal: Nature Communications
PubMed ID: 39920100
Doi: 10.1038/s41467-024-55764-z
Products & Services: Codon Optimization   
Co-translational protein aggregation and ribosome stalling as a broad-spectrum antibacterial mechanism
Authors: Laleh Khodaparast, Ladan Khodaparast, Ramon Duran-Romaña, Guiqin Wu, Bert Houben, Wouter Duverger, Matthias De Vleeschouwer, Katerina Konstantoulea, Fleur Nysen, Thomas Schalck, Daniel J Curwen, Lisandra L Martin, Sebastien Carpentier, Bernard Scorneaux, Jan Michiels, Joost Schymkowitz, Frederic Rousseau
Journal: Nature Communications
PubMed ID: 39939597
Doi: 10.1038/s41467-025-56873-z
Products & Services: Peptide Synthesis   
Cascaded immunotherapy with implantable dual-drug depots sequentially releasing STING agonists and apoptosis inducers
Authors: Kai Li, Xuan Yu, Yanteng Xu, Haixia Wang, Zheng Liu, Chong Wu, Xing Luo, Jiancheng Xu, Youqiang Fang, Enguo Ju, Shixian Lv, Hon Fai Chan, Yeh-Hsing Lao, Weiling He, Yu Tao, Mingqiang Li
Journal: Nature Communications
PubMed ID: 39952937
Doi: 10.1038/s41467-025-56407-7
Products & Services: Recombinant Proteins   
Proteasomes accumulate in the plant apoplast where they participate in microbe-associated molecular pattern (MAMP)-triggered pathogen defense
Authors: Hana Zand Karimi, Kuo-En Chen, Marilee Karinshak, Xilin Gu, Jason K Sello, Richard D Vierstra
Journal: Nature Communications
PubMed ID: 39952938
Doi: 10.1038/s41467-025-56594-3
Products & Services: Peptide Synthesis   
GMRSP encoded by lncRNA H19 regulates metabolic reprogramming and alleviates aortic dissection
Authors: Jizhong Wang, Jitao Liu, Fan Yang, Yinghao Sun, Jiaohua Chen, Jie Liu, Tucheng Sun, Ruixin Fan, Fang Pei, Songyuan Luo, Jie Li, Jianfang Luo
Journal: Nature Communications
PubMed ID: 39966416
Doi: 10.1038/s41467-025-57011-5
Alternatively spliced NFKB1 transcripts enriched in Andean Aymara modulate inflammation, HIF and hemoglobin
Authors: Jihyun Song, Seonggyun Han, Ricardo Amaru, Lucie Lanikova, Teddy Quispe, Dongwook Kim, Jacob E Crawford, Soo Jin Kim, Younghee Lee, Josef T Prchal
Journal: Nature Communications
PubMed ID: 39971917
Doi: 10.1038/s41467-025-56848-0
Products & Services: Protein Electrophoresis and Western   
Autophagy regulates cellular senescence by mediating the degradation of CDKN1A/p21 and CDKN2A/p16 through SQSTM1/p62-mediated selective autophagy in myxomatous mitral valve degeneration.
Authors: Qiyu Tang, Keyi Tang, Greg R Markby, Maciej Parys, Kanchan Phadwal, Vicky E MacRae, Brendan M Corcoran
Journal: Autophagy
PubMed ID: 39988732
Doi: 10.1080/15548627.2025.2469315
Products & Services: CRISPR Plasmids   
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