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G34R cancer mutation alters the conformational ensemble and dynamics of the histone H3.3 tails

Authors: Harrison A Fuchs, Yunhui Peng, Shine Ayyapan, Ruben Rosas, Houfang Zhang, Anna R Panchenko, Catherine A Musselman

Journal: Nucleic Acids Research

PubMed ID: 41533587

Doi: 10.1093/nar/gkaf1381

Products & Services: Mutagenesis Services

Multilayered regulation by RNA thermometers enables precise control of Cas9 expression in E. coli

Authors: Elise K Kammerdiener, Sarah K Garcia, Margaret K Bales, Dawn M Klingeman, Adam M Guss, Richard J Giannone, Robert L Hettich, Carrie A Eckert, William G Alexander

Journal: Nucleic Acids Research

PubMed ID: 41533573

Doi: 10.1093/nar/gkaf1495

Products & Services: Mutant Libraries

Quantitative Proteomics and CRISPR/Cas9 Editing Reveal UPR-Mediated Control of Immunoglobulin Homeostasis in Hybridomas

Authors: Rubing Zou, Xinying Lu, Ying Liu, Peiyu Yang, Shuo Sun, Yihua Liu, Yinyuan Mo, Guonian Zhu, Jae Seong Lee, Yirong Guo

Journal: Advanced Science

PubMed ID: 41560288

Doi: 10.1002/advs.202514140

Products & Services: Protein Electrophoresis and Western

Reversible phase dynamics of PsAF5 regulate mitophagy to balance redox levels in Phytophthora sojae

Authors: Jinzhu Chen, Wenhao Li, Qin Peng, Hongwei Zhu, Tan Dai, Jianqiang Miao, Xili Liu

Journal: SCIENCE ADVANCES

PubMed ID: 41533793

Doi: 10.1126/sciadv.adz2785

Products & Services: Protein and Antibody Isolation

Structural decoding of reversible covalent linkage of odorants in human olfactory receptor OR6A2

Authors: Tian Wang, Yiran Wu, Ling Wang, Shanshan Li, Fei Zhao, Lijie Wu, Yue Liu, Jingzi Qin, Qiwen Tan, Junlin Liu, Liting Zeng, Yilin Chen, Shenyuan Gao, Wenqing Shui, Suwen Zhao, Tian Hua, Zhi-Jie Liu

Journal: Cell

PubMed ID: 41570822

Doi: 10.1016/j.cell.2025.12.017

Products & Services: Protein Electrophoresis and Western

SPARK-seq: A high-throughput platform for aptamer discovery and kinetic profiling

Authors: Guoyan Luo, Jia Song, Yongbo Fu, Yuanjie Jiang, Yuan Gao, Zhixing Zhong, Ling Li, Yong Wei, Hao-Ran Jia, Lu Guo, Ting Fu, Qin Wu, Weihong Tan

Journal: Science (New York, N.Y.)

PubMed ID: 41477891

Doi: 10.1126/science.adv6127

Products & Services: Protein Electrophoresis and Western

Phage-associated Cas12p nucleases require binding to bacterial thioredoxin for activation and cleavage of target DNA

Authors: Zhipeng Wang, Yujue Wang, Hui Gao, Jiani Dai, Na Tang, Yannan Wang, Quanjiang Ji

Journal: Nature Microbiology

PubMed ID: 41492065

Doi: 10.1038/s41564-025-02224-z

Products & Services: Protein Electrophoresis and Western

Antibody-induced internalization and degradation of PLA2R amplifies CD4+ T cell activation

Authors: Yuning Liu, Yinyin Li, Hui Zhou, Jieli Yu, Pei Deng, Weiwei Xu, Bingqian Pan, Lei Zhang, Hong Zhou, Jing Zhang, Xiaohan Liu, Min Shi, Xianchi Dong, Bei Tong, Enguang Bi, Nannan Guo, Yu Hu

Journal: Theranostics

PubMed ID: 41328348

Doi: 10.7150/thno.123035

Products & Services: Gene Synthesis PCR Cloning and Subcloning

Schwann cell-derived extracellular vesicles inhibit osteoclastogenesis through the PTEN/AKT axis in peripheral nerve-bone crosstalk.

Authors: Huijian Yang, Biao Yu, Ruiyang Li, Yang Hong, Mingzhu Shen, Tianzhuo Shen, Xiuhui Wang, Han Liu, Guangchao Wang, Ke Xu, Yuhai Ma, Mengmeng Li, Jiacan Su

Journal: Journal of nanobiotechnology

PubMed ID: 41530784

Doi: 10.1186/s12951-026-04021-0

Products & Services: Protein Electrophoresis and Western

Stress controls heterochromatin inheritance via histone H3 ubiquitylation

Authors: Bharat Bhatt, Yi Wei, Ashis Kumar Pradhan, Jothy Dhakshnamoorthy, Martin Zofall, Hua Xiao, Drisya Vijayakumari, Shweta Jain, Hernan Diego Folco, Hongyun Qi, David A Ball, Tatiana S Karpova, David Wheeler, Jiemin Wong, Shiv I S Grewal

Journal: Nature

PubMed ID: 41501458

Doi: 10.1038/s41586-025-09899-8

Products & Services: Protein and Antibody Isolation