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Discovery of an exosite on the SOCS2-SH2 domain that enhances SH2 binding to phosphorylated ligands
Authors: Edmond M Linossi , Kunlun Li , Gianluca Veggiani , Cyrus Tan , Farhad Dehkhoda , Colin Hockings , Dale J Calleja , Narelle Keating , Rebecca Feltham , Andrew J Brooks , Shawn S Li , Sachdev S Sidhu , Jeffrey J Babon , Nadia J Kershaw , Sandra E Nicholson
Journal: Nat Commun
PubMed ID: 34857742
Doi: s41467-021-26983-5
Products & Services: Peptide Synthesis   
Functional conservation and divergence of the helix-turn-helix motif of E2 ubiquitin-conjugating enzymes
Authors: Kaeli A Welsh, Derek L Bolhuis, Anneroos E Nederstigt, Joshua Boyer, Brenda R S Temple, Thomas Bonacci, Li Gu, Alban Ordureau, J Wade Harper, Joshua P Steimel, Qi Zhang, Michael J Emanuele, Joseph S Harrison, Nicholas G Brown
Journal: EMBO J
PubMed ID: 34942047
Doi: 10.15252/embj.2021108823
SARS-CoV-2 evolved during advanced HIV disease immunosuppression has Beta-like escape of vaccine and Delta infection elicited immunity
Authors: Sandile Cele, Farina Karim, Gila Lustig, James Emmanuel San, Tandile Hermanus, Houriiyah Tegally, Jumari Snyman, Thandeka Moyo-Gwete, Eduan Wilkinson, Mallory Bernstein, Khadija Khan, Shi-Hsia Hwa, Sasha W Tilles, Lavanya Singh, Jennifer Giandhari, Ntombifuthi Mthabela, Matilda Mazibuko, Yashica Ganga, Bernadett I Gosnell, Salim Abdool Karim, Willem Hanekom, Wesley C Van Voorhis, Thumbi Ndung'u, Richard J Lessells, Penny L Moore, Mahomed-Yunus S Moosa, Tulio de Oliveira, Alex Sigal
Journal: medrxiv
PubMed ID: 34909798
Doi: 10.1101/2021.09.14.21263564
Products & Services: Monoclonal Antibody Services   
A single injection of CM1021, a long half-life hepatocyte growth factor mimetic, increases liver mass in mice
Authors:
Journal: Biochem Biophys Rep
PubMed ID: 34977363
Doi: 10.1016/j.bbrep.2021.101186
Products & Services: Plasmid DNA Preparation   
Synthetic antibacterial discovery of symbah-1, a macrocyclic β-hairpin peptide antibiotic
Authors: Justin R Randall, Gillian Davidson, Renee M Fleeman, Santos A Acosta, Ian M Riddington, T Jeffrey Cole, Cory D DuPai, Bryan W Davies
Journal: iScience
PubMed ID: 35005555
Doi: 10.1016/j.isci.2021.103611
Products & Services: Peptide Synthesis   
Mechanistic Insights into the Preference for Tandem Binding Sites in DNA Recognition by FOXM1
Authors: Huajun Zhang, Shuyan Dai, Xujun Liang, Jun Li, Yongheng Chen
Journal: J Mol Biol
PubMed ID: 34973238
Doi: 10.1016/j.jmb.2021.167426
Products & Services: Custom DNA/RNA Oligos   
Molecular structures and conformations of protocadherin-15 and its complexes on stereocilia elucidated by cryo-electron tomography
Authors: Johannes Elferich, Sarah Clark, Jingpeng Ge, April Goehring, Aya Matsui, Eric Gouaux
Journal: Elife
PubMed ID: 34964715
Doi: 10.7554/eLife.74512
Products & Services: Polyclonal Antibody Services   
The Intragenesis and Synthetic Biology Approach towards Accelerating Genetic Gains on Strawberry: Development of New Tools to Improve Fruit Quality and Resistance to Pathogens
Authors: Victoria Súnico, José Javier Higuera, Francisco J Molina-Hidalgo, Rosario Blanco-Portales, Enriqueta Moyano, Antonio Rodríguez-Franco, Juan Muñoz-Blanco, José L Caballero
Journal: Plants (Basel)
PubMed ID: 35009061
Doi: 10.3390/plants11010057
Products & Services: Gene Synthesis   
Impact of Molecular Modifications on the Immunogenicity and Efficacy of Recombinant Raccoon Poxvirus-Vectored Rabies Vaccine Candidates in Mice
Authors: Carly M Malavé, Jaime Lopera-Madrid, Lex G Medina-Magües, Tonie E Rocke, Jorge E Osorio
Journal: Vaccines (Basel)
PubMed ID: 34960182
Doi: 10.3390/vaccines9121436
Products & Services: Plasmid DNA Preparation   
MON-2, a Golgi protein, mediates autophagy-dependent longevity in
Authors: Yoonji Jung, Murat Artan, Nari Kim, Jeonghun Yeom, Ara B Hwang, Dae-Eun Jeong, Özlem Altintas, Keunhee Seo, Mihwa Seo, Dongyeop Lee, Wooseon Hwang, Yujin Lee, Jooyeon Sohn, Eun Ji E Kim, Sungeun Ju, Seong Kyu Han, Hyun-Jun Nam, Linnea Adams, Youngjae Ryu, Dong Jin Moon, Chanhee Kang, Joo-Yeon Yoo, Sang Ki Park, Chang Man Ha, Malene Hansen, Sanguk Kim, Cheolju Lee, Seung-Yeol Park, Seung-Jae V Lee
Journal: Sci Adv
PubMed ID: 34860542
Doi: 10.1126/sciadv.abj8156
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