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Epsin1 enforces a condensation-dependent checkpoint for ubiquitylated cargo during clathrin-mediated endocytosis

Authors: Susovan Sarkar, Hao-Yang Liu, Feng Yuan, Brandon T Malady, Liping Wang, Eileen M Lafer, Jessica Perez, Jon M Huibregtse, Jeanne C Stachowiak

Journal: Nature Communications

PubMed ID: 40854908

Doi: 10.1038/s41467-025-63238-z.

Products & Services: Custom Vector Construction

Heme allocation in eukaryotic cells relies on mitochondrial heme export through FLVCR1b to cytosolic GAPDH

Authors: Dhanya Thamaraparambil Jayaram, Pranav Sivaram, Pranjal Biswas, Yue Dai, Elizabeth A Sweeny, Dennis J Stuehr

Journal: Nature Communications

PubMed ID: 40858607

Doi: 10.1038/s41467-025-62819-2.

Products & Services: Custom Vector Construction

Nascent liver proteome reveals enzymes and transcription regulators under physiological and alcohol exposure conditions

Authors: Jiayu Gu, Lihui Lao, Linzhen Hu, Jia Zang, Chao Liu, Ruixi Wan, Ling Tang, Ying Yuan, Yulin Chen, Shixian Lin

Journal: Nature Communications

PubMed ID: 40858584

Doi: 10.1038/s41467-025-63212-9.

Products & Services: Protein and Antibody Isolation

Standardizing a Protocol for Streamlined Synthesis and Characterization of Lipid Nanoparticles to Enable Preclinical Research and Education

Authors: Shilpi Agrawal, Abbey L Stokes, Christopher E Nelson

Journal: biorxiv

PubMed ID: 40766677

Doi: 10.1101/2025.07.31.667476

Products & Services: Catalog IVT RNA products

Systemic vaccination induces CD8 + T cells and remodels the tumor microenvironment

Authors: Faezzah Baharom; Ramiro A. Ramirez-Valdez; Ahad Khalilnezhad; Shabnam Khalilnezhad; Marlon Dillon; Dalton Hermans; Sloane Fussell; Kennedy K.S. Tobin; Charles-Antoine Dutertre; Geoffrey M. Lynn; S ren M ller; Florent Ginhoux; Andrew S. Ishizuka; Robert A. Seder

Journal: Cell

PubMed ID: 36302380

Doi: 10.1016/j.cell.2022.10.006

Products & Services: Peptide Synthesis

Systemic vaccination induces CD8 + T cells and remodels the tumor microenvironment

Journal: Cell

PubMed ID: 36302380

Doi: 10.1016/j.cell.2022.10.006

Products & Services: Peptide Synthesis

AI-Guided Dual Strategy for Peptide Inhibitor Design Targeting Structural Polymorphs of -Synuclein Fibrils

Authors: Jinfang Duan; Haoyu Zhang; Chuanqi Sun

Journal: Cells

PubMed ID: 41369409

Doi: 10.3390/cells14231921

Products & Services: Peptide Synthesis

Identification of 14-3 3 Proteins as Binding Partners of TRP Channels

Authors: Nicol s Pe a-Vilches; Mariela Gonz lez-Avenda o; Nicole Soto-Garc a; Diego Maureira; Ian Silva; Javiera Avil s; El as Manr quez-Ben tez; Exequiel Medina; Oscar Cerda; Pablo Galaz-Davison; Ariela Vergara-Jaque

Journal: Journal of chemical information and modeling

PubMed ID: 41839059

Doi: 10.1021/acs.jcim.6c00092

DUX4 is a multifunctional factor priming human embryonic genome activation

Authors: Sanna Vuoristo; Shruti Bhagat; Christel Hyd n-Granskog; Masahito Yoshihara; Lisa Gawriyski; Eeva-Mari Jouhilahti; Vipin Ranga; Mahlet Tamirat; Mikko Huhtala; Ida Kirjanov; Sonja Nyk nen; Kaarel Krjut kov; Anastassius Damdimopoulos; Jere Weltner; Kosuke Hashimoto; Ga lle Recher; Sini Ezer; Priit Paluoja; Pauliina Paloviita; Yujiro Takegami; Ai Kanemaru; Karolina Lundin; Tomi T. Airenne; Timo Otonkoski; Juha S. Tapanainen; Hideya Kawaji; Yasuhiro Murakawa; Thomas R. B rglin; Markku Varjosalo; Mark S. Johnson; Timo Tuuri; Shintaro Katayama; Juha Kere

Journal: iScience

PubMed ID: 35402882

Doi: 10.1016/j.isci.2022.104137

Products & Services: Peptide Synthesis

14-3-3 interaction with phosphodiesterase 8A sustains PKA signaling and downregulates the MAPK pathway

Authors: Soumita Mukherjee; Somesh Roy; Shruti Mukherjee; Amaravadhi Harikishore; Anirban Bhunia; Atin K. Mandal

Journal: The Journal of Biological Chemistry

PubMed ID: 38325743

Doi: 10.1016/j.jbc.2024.105725