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Ligand-directed bias of G protein signaling at the dopamine D2 receptor
Authors: Ee Von Moo , Kasper Harpsøe , Alexander S Hauser , Ikuo Masuho , Hans Bräuner-Osborne , David E Gloriam , Kirill A Martemyanov
Journal: Cell Chem Biol .
PubMed ID: 34302750
Doi: 10.1016/j.chembiol.2021.07.004
Products & Services: Mutagenesis Services   Gene Synthesis   
SARS-CoV-2 Variants Increase Kinetic Stability of Open Spike Conformations as an Evolutionary Strategy
Authors: Ziwei Yang, Yang Han, Shilei Ding, Wei Shi, Tongqing Zhou, Andrés Finzi, Peter D Kwong, Walther Mothes, Maolin Lu
Journal: MBio
PubMed ID: 35164561
Doi: 10.1128/mbio.03227-21
Products & Services: Gene Synthesis   
Germinal centre-driven maturation of B cell response to mRNA vaccination
Authors: Wooseob Kim, Julian Q Zhou, Stephen C Horvath, Aaron J Schmitz, Alexandria J Sturtz, Tingting Lei, Zhuoming Liu, Elizaveta Kalaidina, Mahima Thapa, Wafaa B Alsoussi, Alem Haile, Michael K Klebert, Teresa Suessen, Luis Parra-Rodriguez, Philip A Mudd, Sean P J Whelan, William D Middleton, Sharlene A Teefey, Iskra Pusic, Jane A O'Halloran, Rachel M Presti, Jackson S Turner, Ali H Ellebedy
Journal: Nature
PubMed ID: 35168246
Doi: 10.1038/s41586-022-04527-1
Products & Services: Plasmid DNA Preparation   
Disentangling the recognition complexity of a protein hub using a nanopore
Authors: Lauren Ashley Mayse, Ali Imran, Motahareh Ghahari Larimi, Michael S Cosgrove, Aaron James Wolfe, Liviu Movileanu
Journal: Nat Commun
PubMed ID: 35190547
Doi: 10.1038/s41467-022-28465-8
Products & Services: Plasmid DNA Preparation   
Mutant glucocerebrosidase impairs α-synuclein degradation by blockade of chaperone-mediated autophagy
Authors: Sheng-Han Kuo, Inmaculada Tasset, Melody M Cheng, Antonio Diaz, Ming-Kai Pan, Ori J Lieberman, Samantha J Hutten, Roy N Alcalay, Sangjun Kim, Pilar Ximénez-Embún, Li Fan, Donghoon Kim, Han Seok Ko, Talene Yacoubian, Ellen Kanter, Ling Liu, Guomei Tang, Javier Muñoz, Sergio Pablo Sardi, Aiqun Li, Li Gan, Ana Maria Cuervo, David Sulzer
Journal: Sci Adv
PubMed ID: 35138901
Doi: 10.1126/sciadv.abm6393
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Humoral Immunity to Allogeneic Immunoproteasome-Expressing Mesenchymal Stromal Cells Requires Efferocytosis by Endogenous Phagocytes
Authors: Jean-Pierre Bikorimana, Jamilah Abusarah, Natasha Salame, Nehme El-Hachem, Riam Shammaa, Moutih Rafei
Journal: Cells
PubMed ID: 35203247
Doi: 10.3390/cells11040596
Products & Services: Peptide Synthesis   
CNOT6: A Novel Regulator of DNA Mismatch Repair
Authors: Peng Song, Shaojun Liu, Dekang Liu, Guido Keijzers, Daniela Bakula, Shunlei Duan, Niels de Wind, Zilu Ye, Sergey Y Vakhrushev, Morten Scheibye-Knudsen, Lene Juel Rasmussen
Journal: Cells
PubMed ID: 35159331
Doi: 10.3390/cells11030521
Products & Services: Plasmid DNA Preparation   
mRNA COVID-19 vaccine booster fosters B- and T-cell responses in immunocompromised patients
Authors: Elena Azzolini, Chiara Pozzi, Luca Germagnoli, Bianca Oresta, Nicola Carriglio, Mariella Calleri, Carlo Selmi, Maria De Santis, Silvia Finazzi, Carmelo Carlo-Stella, Alexia Bertuzzi, Francesca Motta, Angela Ceribelli, Alberto Mantovani, Fabrizio Bonelli, Maria Rescigno
Journal: Life Sci Alliance
PubMed ID: 35169017
Doi: 10.26508/lsa.202201381
Alteration of the translational readthrough isoform AQP4ex induces redistribution and downregulation of AQP4 in human glioblastoma
Authors: Onofrio Valente, Raffaella Messina, Giuseppe Ingravallo, Emilio Bellitti, Domenico Sergio Zimatore, Luigi de Gennaro, Pasqua Abbrescia, Roberta Pati, Claudia Palazzo, Grazia Paola Nicchia, Maria Trojano, Francesco Signorelli, Antonio Frigeri
Journal: Cell Mol Life Sci
PubMed ID: 35187599
Doi: 10.1007/s00018-021-04123-y
Products & Services: Gene Synthesis   
Overexpression of m6A-factors METTL3, ALKBH5, and YTHDC1 alters HPV16 mRNA splicing
Authors: Xiaoxu Cui, Kersti Nilsson, Naoko Kajitani, Stefan Schwartz
Journal: Virus Genes
PubMed ID: 35190939
Doi: 10.1007/s11262-022-01889-6
Products & Services: Gene Synthesis   

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