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Convergent epitope specificities, V gene usage and public clones elicited by primary exposure to SARS-CoV-2 variants
Authors: Noemia S Lima, Maryam Mukhamedova, Timothy S Johnston, Danielle A Wagner, Amy R Henry, Lingshu Wang, Eun Sung Yang, Yi Zhang, Kevina Birungi, Walker P Black, Sijy O'Dell, Stephen D Schmidt, Damee Moon, Cynthia G Lorang, Bingchun Zhao, Man Chen, Kristin L Boswell, Jesmine Roberts-Torres, Rachel L Davis, Lowrey Peyton, Sandeep R Narpala, Sarah O'Connell, Jennifer Wang, Alexander Schrager, Chloe Adrienna Talana, Kwanyee Leung, Wei Shi, Rawan Khashab, Asaf Biber, Tal Zilberman, Joshua Rhein, Sara Vetter, Afeefa Ahmed, Laura Novik, Alicia Widge, Ingelise Gordon, Mercy Guech, I-Ting Teng, Emily Phung, Tracy J Ruckwardt, Amarendra Pegu, John Misasi, Nicole A Doria-Rose, Martin Gaudinski, Richard A Koup, Peter D Kwong, Adrian B McDermott, Sharon Amit, Timothy W Schacker, Itzchak Levy, John R Mascola, Nancy J Sullivan, Chaim A Schramm, Daniel C Douek
Journal: biorxiv
PubMed ID: 35378757
Doi: 10.1101/2022.03.28.486152
Products & Services: Peptide Synthesis   
Adjusted degradation of BRD4 S and BRD4 L based on fine structural modifications of the pyrrolopyridone scaffold
Authors: Jingjing Chen, Huixin He, Aihuan Wei, Yalei Li, Gang Cheng, Hui Qin, Hanyue Zhong, Hongchun Liu, Meiyu Geng, Aijun Shen, Youhong Hu
Journal: Eur J Med Chem
PubMed ID: 35395439
Doi: 10.1016/j.ejmech.2022.114259
Rapid Exchange of Stably Bound Protein and DNA Cargo on a DNA Origami Receptor
Authors: James W P Brown, Rokiah G Alford, James C Walsh, Richard E Spinney, Stephanie Y Xu, Sophie Hertel, Jonathan F Berengut, Lisanne M Spenkelink, Antoine M van Oijen, Till Böcking, Richard G Morris, Lawrence K Lee
Journal: ACS Nano
PubMed ID: 35316035
Doi: 10.1021/acsnano.2c00699
Products & Services: Custom Vector Construction   
Induction of broadly neutralizing antibodies using a secreted form of the hepatitis C virus E1E2 heterodimer as a vaccine candidate
Authors: Ruixue Wang, Saori Suzuki, Johnathan D Guest, Brigitte Heller, Maricar Almeda, Alexander K Andrianov, Alexander Marin, Roy A Mariuzza, Zhen-Yong Keck, Steven K H Foung, Abdul S Yunus, Brian G Pierce, Eric A Toth, Alexander Ploss, Thomas R Fuerst
Journal: Proc Natl Acad Sci U S A
PubMed ID: 35263223
Doi: 10.1073/pnas.2112008119
Products & Services: PCR Cloning and Subcloning   
In situ solid-state NMR study of antimicrobial peptide interactions with erythrocyte membranes
Authors: Kiran Kumar, Mathew Sebastiao, Alexandre A Arnold, Steve Bourgault, Dror E Warschawski, Isabelle Marcotte
Journal: Biophys J
PubMed ID: 35278426
Doi: 10.1016/j.bpj.2022.03.009
Products & Services: Peptide Synthesis   
Coupling cell growth and biochemical pathway induction in Saccharomyces cerevisiae for production of (+)-valencene and its chemical conversion to (+)-nootkatone
Authors: Ziling Ye, Yanglei Huang, Bin Shi, Zilei Xiang, Zhu Tian, Man Huang, Liangliang Wu, Zixin Deng, Kun Shen, Tiangang Liu
Journal: Metab Eng
PubMed ID: 35296429
Doi: 10.1016/j.ymben.2022.03.005
Products & Services: PCR and Cloning   
Structure of the decoy module of human glycoprotein 2 and uromodulin and its interaction with bacterial adhesin FimH
Authors: Alena Stsiapanava, Chenrui Xu, Shunsuke Nishio, Ling Han, Nao Yamakawa, Marta Carroni, Kathryn Tunyasuvunakool, John Jumper, Daniele de Sanctis, Bin Wu, Luca Jovine
Journal: Nat Struct Mol Biol
PubMed ID: 35273390
Doi: 10.1038/s41594-022-00729-3
Products & Services: Mutant Libraries   
MERS-CoV ORF4b employs an unusual binding mechanism to target IMPα and block innate immunity
Authors: Thilini S Munasinghe, Megan R Edwards, Sofiya Tsimbalyuk, Olivia A Vogel, Kate M Smith, Murray Stewart, Justin K Foster, Loretta A Bosence, David Aragão, Justin A Roby, Christopher F Basler, Jade K Forwood
Journal: Nat Commun
PubMed ID: 35338144
Doi: 10.1038/s41467-022-28851-2
Products & Services: Bacterial Expression   
Co-targeting of BAX and BCL-XL proteins broadly overcomes resistance to apoptosis in cancer
Authors: Andrea Lopez, Denis E Reyna, Nadege Gitego, Felix Kopp, Hua Zhou, Miguel A Miranda-Roman, Lars Ulrik Nordstrøm, Swathi-Rao Narayanagari, Ping Chi, Eduardo Vilar, Aristotelis Tsirigos, Evripidis Gavathiotis
Journal: Nat Commun
PubMed ID: 35256598
Doi: 10.1038/s41467-022-28741-7
Products & Services: Catalog Peptides   
The non-ELR CXC chemokine encoded by human cytomegalovirus UL146 genotype 5 contains a C-terminal β-hairpin and induces neutrophil migration as a selective CXCR2 agonist
Authors: Christian Berg, Michael J Wedemeyer, Motiejus Melynis, Roman R Schlimgen, Lasse H Hansen, Jon Våbenø, Francis C Peterson, Brian F Volkman, Mette M Rosenkilde, Hans R Lüttichau
Journal: PLoS Pathog
PubMed ID: 35271688
Doi: 10.1371/journal.ppat.1010355
Products & Services: Custom Vector Construction   

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