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Structural basis for receptor selectivity and inverse agonism in S1P receptors
Authors: Elizaveta Lyapina, Egor Marin, Anastasiia Gusach, Philipp Orekhov, Andrey Gerasimov, Aleksandra Luginina, Daniil Vakhrameev, Margarita Ergasheva, Margarita Kovaleva, Georgii Khusainov, Polina Khorn, Mikhail Shevtsov, Kirill Kovalev, Sergey Bukhdruker, Ivan Okhrimenko, Petr Popov, Hao Hu, Uwe Weierstall, Wei Liu, Yunje Cho, Ivan Gushchin, Andrey Rogachev, Gleb Bourenkov, Sehan Park, Gisu Park, Hyo Jung Hyun, Jaehyun Park, Valentin Gordeliy, Valentin Borshchevskiy, Alexey Mishin, Vadim Cherezov
Journal: Nat Commun
PubMed ID: 35961984
Doi: 10.1038/s41467-022-32447-1
Products & Services: Mammalian Expression   
Strong T-cell activation in response to COVID-19 vaccination in multiple sclerosis patients receiving B-cell depleting therapies
Authors: Roberto Alfonso-Dunn, Jerry Lin, Vanessa Kirschner, Joyce Lei, Grant Feuer, Michaela Malin, Jiayuan Liu, Morgan Roche, Saud A Sadiq
Journal: Front Immunol
PubMed ID: 35990701
Doi: 10.3389/fimmu.2022.926318
CpG content in the Zika virus genome affects infection phenotypes in the adult brain and fetal lymph nodes
Authors: Daniel Udenze, Ivan Trus, Nathalie Berube, Uladzimir Karniychuk
Journal: Front Immunol
PubMed ID: 35983032
Doi: 10.3389/fimmu.2022.943481
Products & Services: GenParts™ DNA Fragments   
Engineering an adenine base editor in human embryonic stem cells with minimal DNA and RNA off-target activities
Authors: Zhenwu Zhang, Wanyu Tao, Shisheng Huang, Wenjun Sun, Yue Wang, Wen Jiang, Xingxu Huang, Chao-Po Lin
Journal: Mol Ther Nucleic Acids
PubMed ID: 35991312
Doi: 10.1016/j.omtn.2022.07.026
Products & Services: GenParts™ DNA Fragments   
Membrane transporters control cerebrospinal fluid formation independently of conventional osmosis to modulate intracranial pressure
Authors: Eva K Oernbo, Annette B Steffensen, Pooya Razzaghi Khamesi, Trine L Toft-Bertelsen, Dagne Barbuskaite, Frederik Vilhardt, Niklas J Gerkau, Katerina Tritsaris, Anja H Simonsen, Sara D Lolansen, Søren N Andreassen, Steen G Hasselbalch, Thomas Zeuthen, Christine R Rose, Vartan Kurtcuoglu, Nanna MacAulay
Journal: Fluids Barriers CNS
PubMed ID: 36038945
Doi: 10.1186/s12987-022-00358-4
Products & Services: Gene Synthesis   
Signal Peptide-rheostat Dynamics Delay Secretory Preprotein Folding
Authors: Dries Smets, Jochem Smit, Ying Xu, Spyridoula Karamanou, Anastassios Economou
Journal: J Mol Biol
PubMed ID: 35970402
Doi: 10.1016/j.jmb.2022.167790
Products & Services: Custom Vector Construction   
Effects of boosted mRNA and adenoviral-vectored vaccines on immune responses to omicron BA1 and BA2 following the heterologous CoronaVac/AZD1222 vaccination
Authors: Nungruthai Suntronwong, Sitthichai Kanokudom, Chompoonut Auphimai, Suvichada Assawakosri, Thanunrat Thongmee, Preeyaporn Vichaiwattana, Thaneeya Duangchinda, Warangkana Chantima, Pattarakul Pakchotanon, Jira Chansaenroj, Jiratchaya Puenpa, Pornjarim Nilyanimit, Donchida Srimuan, Thaksaporn Thatsanatorn, Natthinee Sudhinaraset, Nasamon Wanlapakorn, Juthathip Mongkolsapaya, Yong Poovorawan
Journal: J Med Virol
PubMed ID: 35924475
Doi: 10.1002/jmv.28044
Products & Services: Proteins, Expression, Isolation and Analysis   
The antibody landscapes following AS03 and MF59 adjuvanted H5N1 vaccination
Authors: Johannes B Goll, Aarti Jain, Travis L Jensen, Rafael Assis, Rie Nakajima, Algis Jasinskas, Lynda Coughlan, Sami R Cherikh, Casey E Gelber, S Khan, D Huw Davies, Philip Meade, Daniel Stadlbauer, Shirin Strohmeier, Florian Krammer, Wilbur H Chen, Philip L Felgner
Journal: npj Vaccines
PubMed ID: 36042229
Doi: 10.1038/s41541-022-00524-7
Products & Services: Proteins, Expression, Isolation and Analysis   
A cytoskeletal vortex drives phage nucleus rotation during jumbo phage replication in E coli
Authors: Erica A Birkholz, Thomas G Laughlin, Emily Armbruster, Sergey Suslov, Jina Lee, Johannes Wittmann, Kevin D Corbett, Elizabeth Villa, Joe Pogliano
Journal: Cell Rep
PubMed ID: 35977483
Doi: 10.1016/j.celrep.2022.111179
Products & Services: Plasmid DNA Preparation   
Translational potential of base-editing tools for gene therapy of monogenic diseases
Authors: Vasiliy V Reshetnikov, Angelina V Chirinskaite, Julia V Sopova, Roman A Ivanov, Elena I Leonova
Journal: Front Bioeng Biotechnol
PubMed ID: 36032737
Doi: 10.3389/fbioe.2022.942440
Products & Services: Codon Optimization   

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