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A Molecular Mechanism for the Reduction of the Cu Site in Lytic Polysaccharide Monooxygenases by Phenol Reductants

Authors: Langxing Liao, Jian Kuang, Peng Wu, Xianhang Sang, Heng Yin, Changlin Ti, Kingwang Zhang, Wei Peng, Lu Yu, Binju Wang

Journal: JACS Au

Doi: 10.1021/jacsau.5c00562

Products & Services: Gene Synthesis

AMPGen: an evolutionary information-reserved and diffusion-driven generative model for de novo design of antimicrobial peptides

Authors: Shuwen Jin, Zihan Zeng, Xiyan Xiong, Baicheng Huang, Li Tang, Hongsheng Wang, Xiao Ma, Xiaochun Tang, Guoqing Shao, Xingxu Huang, Feng Lin

Journal: Communications Biology

PubMed ID: 40447738

Doi: 10.1038/s42003-025-08282-7

Products & Services: Peptide Synthesis

Constitutive arrestin recruitment by orphan GPR52 via an atypical binding mode

Authors: Xi Lin, Xiaohu Wei, Ning Pu, Ling Wang, Zhibin Zhang, Cuixia Li, Yang Yue, Junlin Liu, Qiwen Tan, Qianqian Sun, Fei Xu

Journal: Cell Research

PubMed ID: 40813798

Doi: 10.1038/s41422-025-01165-w

Products & Services: Protein and Antibody Isolation

E. coli-mediated expedient biosynthesis of biotin-labeled ubiquitin probe enables activity-based profiling of deubiquitinases in cytoplasmic and nuclear compartments

Authors: Shuai Peng, Shaowen Wang, Xiaotong Liu, Hongrui Xu, Guoqiang Xu, Jia-bin Li

Journal: Chinese Chemical Letters

Doi: 10.1016/j.cclet.2025.111760

Products & Services: Codon Optimization Gene Synthesis PCR Cloning and Subcloning

Retrograde transport of neurotrophin receptor TrkB-FL inducedby excitotoxicity regulates Golgi stability and is a target forstroke neuroprotection

Authors: Gema María Esteban-Ortega, Elena Torres-Campos, Margarita Díaz-Guerra

Journal: Cell death & disease

PubMed ID: 40883288

Doi: 10.1038/s41419-025-07990-6

Products & Services: Peptide Synthesis Protein and Antibody Isolation

Viral evolution prediction identifies broadly neutralizing antibodies to existing and rospective SARS-CoV-2 variants

Authors: Fanchong Jian, Anna Z Wec, Leilei Feng, Yuanling Yu, Lei Wang, Peng Wang, Lingling Yu, Jing Wang, Jacob Hou, Daniela Montes Berrueta, Diana Lee, Tessa Speidel, LingZhi Ma, Thu Kim, Ayijiang Yisimayi, Weiliang Song, Lu Liu, Sijie Yang, Xiao Niu, Tianhe Xiao, Ran An, Yao Wang, Fei Shao, Youchun Wang, Simone Pecetta, Xiangxi Wang, Laura M Walker, Yunlong Cao

Journal: Nature Microbiology

PubMed ID: 40494884

Doi: 10.1038/s41564-025-02030-7

Products & Services: Gene Synthesis Codon Optimization

USP17L promotes the 2-cell-like program through deubiquitination of H2AK119ub1 and ZSCAN4

Authors: Panpan Shi, Xukun Lu, Kairang Jin, Linlin Liu, Guoxing Yin, Wenying Wang, Jiao Yang, Lijuan Wang, Lijun Dong, Wei Xie, Lin Liu

Journal: Nature Communications

PubMed ID: 40750602

Doi: 10.1038/s41467-025-62303-x.

Products & Services: Polyclonal Antibody Services

GTP hydrolysis triggers membrane remodeling by AMPH-1

Authors: Wei Gai https://orcid.org/0009-0005-5681-7380, Yuhang Wang https://orcid.org/0000-0002-8048-138X, Brianna Martin, Junjie Zhang https://orcid.org/0000-0002-7912-0819, Chavela M. Carr https://orcid.org/0009-0005-1292-1119, and Hays S. Rye

Journal: SCIENCE ADVANCES

PubMed ID: 40749062

Doi: 10.1126/sciadv.ads9443

Products & Services: Protein and Antibody Isolation

The EMC acts as a chaperone for membrane proteins

Authors: Carolin J Klose, Kevin M Meighen-Berger, Martin Kulke, Marina Parr, Barbara Steigenberger, Martin Zacharias, Dmitrij Frishman, Matthias J Feige

Journal: Nature Communications

PubMed ID: 40753078

Doi: 10.1038/s41467-025-62109-x

Products & Services: Catalog Antibodies

Lung metastasis and recurrence is mitigated by CARmacrophages, in-situ-generated from mRNA delivered by small extracellular vesicles

Authors: Yuchen Xiao, Tianchuan Zhu, Zhenxing Chen, Xi Huang

Journal: Nature Communications

PubMed ID: 40759657

Doi: 10.1038/s41467-025-62506-2

Products & Services: Custom DNA/RNA Oligos