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Organ-specific delivery of an mRNA-encoded bispecific T cell engager targeting glypican-3 in hepatocellular carcinoma

Authors: Yan Huang, Shaoli Liu, Xiaoju Zhang, Bingxu Zhang, Feng Shi, Jia Zhang, Shuaibo Shao, Hongya Han, Xiaoyun Ma, Jing Xie, Jianqi Zhang, Hongxiaoying Yu, Yongchao Zhao, Jiazheng Jin, Dong Xu, Liang Liu, Jianing Wang, Yu Tan, Kelu Xu, Lushuai Jin, Quanjun Du, Yifeng Geng, Andong Liu, Wei Xu

Journal: Nature Communications

PubMed ID: 41397962

Doi: 10.1038/s41467-025-66087-y

Products & Services: Custom Vector Construction

Molecular insights into ligand recognition and signaling of OXGR1

Authors: Aijun Liu, Yezhou Liu, Yuanzhengyang Long, Richard D Ye

Journal: Nature Communications

PubMed ID: 41413034

Doi: 10.1038/s41467-025-67101-z

Products & Services: Protein and Antibody Isolation

Cynarin as a potent anti‑osteolytic agent: Targeting MAPK and Nrf2‑Keap1 pathways for osteoclast inhibition and bone protection

Authors: Rui Chao, Yexin Wang, Zhan Liu, Tianhao Wan, Yi Mao, Xinru Xie, Lei Sun, Weifeng Xu, Xuzhuo Chen, Shanyong Zhang

Journal: INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

PubMed ID: PMC12488209

Doi: 10.3892/ijmm.2025.5647

Products & Services: Protein and Antibody Isolation

Excessive vigorous exercise impairs cognitive function through a muscle-derived mitochondrial pretender

Authors: Yan Huang, Biao Hu, Ya Liu, Ling-Qi Xie, Yu Dai, Yu-Ze An, Xin-Yi Peng, Ya-Lun Cheng, Yi-Fan Guo, Wei-Hong Kuang, Yao Xiao, Xin Chen, Yong-Jun Zheng, Gen-Qing Xie, Jian-Ping Wang, Hui Peng, Xiang-Hang Luo

Journal: Cell metabolism

PubMed ID: 41344322

Doi: doi.org/10.1016/j.cmet.2025.11.002

Products & Services: Nucleic Acid Purification

RING- Type E3 Ligase OsRFPH2- 6 Ubiquitinates Nuclear Factor Y Subunit OsNF- YA1 to Suppress Rice Immunity

Authors: Yan Bi, Leeza Tariq, Hui Wang, Yuqing Yan, Dayong Li, Fengming Song

Journal: Molecular plant pathology

PubMed ID: 41424058

Doi: 10.1111/mpp.70193

Products & Services: Catalog Antibodies

Semi-inductive dataset construction and framework optimization for practical drug target interaction prediction with ScopeDTI

Authors: Yigang Chen; Xiang Ji; Ziyue Zhang; Zihao Zhu; Yuming Zhou; Chang Su; Yang-Chi-Dung Lin; Hsi-Yuan Huang; Kangping Wei; Yi Lai; Ke Chen; Xingqiao Lin; Yangyi Zhang; Jiehui Fu; Yixian Huang; Shidong Cui; Shih-Chung Yen; Tao Zhang; Arieh Warshel; Hsien-Da Huang

Journal: Nature Communications

PubMed ID: 41390462

Doi: 10.1038/s41467-025-66311-9

Products & Services: Protein Electrophoresis and Western

Structural basis of Neisseria meningitidis quinol dependent nitric oxide reductase activation by dimerization

Authors: Chai C. Gopalasingam; Haruka Egami; Hideki Shigematsu; Masatora Sakaue; Kouki Fukumoto; Christoph Gerle; Masaki Yamamoto; Yoshitsugu Shiro; Kazumasa Muramoto; Takehiko Tosha

Journal: Communications Biology

PubMed ID: 41896389

Doi: 10.1038/s42003-026-09754-0

Products & Services: Plasmid DNA Preparation

From Multi-Species Screening to Targeted Investigation: Discovery of ACE Inhibitory Peptides in Gigantidas platifrons via Peptidomics, Virtual Screening, and Molecular Dynamics Simulations

Authors: Haorui Zhang; Yuhong Ouyang; Qishan Suo; Hao Chen; Jie Cui; Yang Yue

Journal: Molecules

PubMed ID: 41828750

Doi: 10.3390/molecules31050757

Products & Services: Peptide Synthesis

Targeting Protein Protein Interactions (PPIs) to Drive Functional Annotation: An Integrative Methodology to Study Senescence-Associated PPIs Using TMPRSS11a as Model Interactor

Authors: Roberto Rosales-Rojas; Christian Fern ndez; Mariela Gonz lez-Avenda o; Ariela Vergara-Jaque; M nica C ceres

Journal: Biomolecules

PubMed ID: 42194062

Doi: 10.3390/biom16050714

Nuclear effects play an important role in determining codon usage-dependent human gene expression

Authors: Renu Garg, Pancheng Xie, Jiabin Duan, Huan Liu, Yi Liu

Journal: Nature Communications

PubMed ID: 41339630

Doi: 10.1038/s41467-025-65907-5

Products & Services: Gene Synthesis