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Chemokines kill bacteria without triggering antimicrobial resistance by binding anionic phospholipids

Authors: Sergio M Pontejo, Sophia Martinez, Allison Zhao, Kevin Barnes, Jaime de Anda, Haleh Alimohamadi, Ernest Y Lee, Acacia F Dishman, Brian F Volkman, Gerard C L Wong, David N Garboczi, Angela Ballesteros, Philip M Murphy

Journal: SCIENCE ADVANCES

PubMed ID: 40479071

Doi: 10.1126/sciadv.ads2675

Products & Services: Plasmid DNA Preparation

ATP13A1 engages SEC61 to facilitate substrate-specific translocation

Authors: Xiaoyan Yang, Yi Li, Chengxi Yang, Tingting Li, Zhiyu Fang, Zhigang Feng, Jun Liao, Yan Zou

Journal: SCIENCE ADVANCES

PubMed ID: 40498833

Doi: 10.1126/sciadv.adt1346

Products & Services: Protein and Antibody Isolation

Synthetic biology-driven induction of mature TLS formation enhances antitumor immunity in colorectal cancer

Authors: Ze Mi, Juan Chen, Zhewen Zhang, Jiahao Liu, Yiyi Lei, Hongpei Tan, Wei Li, Xiaoyuan Chen, Pengfei Rong

Journal: SCIENCE ADVANCES

PubMed ID: 40531967

Doi: 10.1126/scitranslmed.ado8395

Products & Services: DNA Sequencing

HIV-1 binds dynein directly to hijack microtubule transport machinery

Authors: Somayesadat Badieyan, Drew Lichon, Sevnur Komurlu Keceli, Michael P Andreas, John P Gillies, Wang Peng, Jiong Shi, Morgan E DeSantis, Christopher R Aiken, Till Böcking, Tobias W Giessen, Edward M Campbell, Michael A Cianfrocco

Journal: SCIENCE ADVANCES

PubMed ID: 40532013

Doi: 10.1126/sciadv.adn6796

Monoclonal antibodies targeting the FimH adhesin protect against uropathogenic E. coli UTI

Authors: Edward D B Lopatto, Jesús M Santiago-Borges, Denise A Sanick, Sameer Kumar Malladi, Philippe N Azimzadeh, Morgan W Timm, Isabella F Fox, Aaron J Schmitz, Jackson S Turner, Shaza M Sayed Ahmed, Lillian Ortinau, Nathaniel C Gualberto, Jerome S Pinkner, Karen W Dodson, Ali H Ellebedy, Andrew L Kau, Scott J Hultgren

Journal: SCIENCE ADVANCES

PubMed ID: 40540557

Doi: 10.1126/sciadv.adw0698

Products & Services: Custom Vector Construction

Inhalable Artificial Polymeric Nucleases Degrading Neutrophil Extracellular Trap-DNAs and Alleviating Pulmonary Fibrosis

Authors: Yibo Du, Chenxu Zhu, Ruifeng Wang, Shi Chen, Chuang Li, Defang OuYang, Lixin Liu, Yongming Chen

Journal: Advanced Science

PubMed ID: 40539399

Doi: 10.1002/advs.202505357

Lysosomal Cathepsin S Escape Facilitates Near Infrared Light-Triggered Pyroptosis Via an Antibody-Indocyanine Green Conjugate

Authors: Fan Chen, Xue-Fei Tian, Teng Yang, Yu-Jie Dai, Da-Yuan Chen, Hong-Bo Chen, Takaya Shimura, Xin-Fang Li, Chu-Lin Sha, Qing Ji, Jun Cao, Mei-Yu Fang, Jin-Biao Shang, Jian-Min Fang, Ye Lu, Wei-Hui Zheng, Peng Guo, Wei-Hong Tan

Journal: Advanced Science

PubMed ID: 40539828

Doi: 10.1002/advs.202504851

Products & Services: Monoclonal Antibody Services

Topoisomerase I Inhibition in ETV4-overexpressed Non-Small Cell Lung Cancer Promotes Replication and Transcription Mediated R-Loop Accumulation and DNA Damage

Authors: Jiaxi Zhang, Yan Wang, Shanhu Cao, Shelly M Xie, Bei Liu, Yimeng Li, Yuqi Hou, Xue Meng, Mingzhu Ruan, Di Bu, Jia Kang, Ruxin Li, Lei Lou, Juan Wang, Lingxiao Xing

Journal: Advanced Science

PubMed ID: 40548893

Doi: 10.1002/advs.202409307

Products & Services: PCR Cloning and Subcloning

Coordinated early immune response in the lungs is required for effective control of SARS-CoV-2 replication

Authors: Klara Lenart, Hendrik Feuerstein, Mariana Prado Marmorato, Laura Perez Vidakovics, Gerald McInerney, Mimi Guebre-Xabier, Jessica F Trost, Bengt Eriksson, Gale Smith, Nita Patel, Karin Loré

Journal: Nature Communications

PubMed ID: 40562777

Doi: 10.1038/s41467-025-60885-0

Products & Services: Gene Synthesis

A rationally designed injury kidney targeting peptide library and its application in rescuing acute kidney injury

Authors: Yushuo Xiao, Zhijian Tong, Huidie Xu, Zhouyan Jia, Chen Wang, Yang Cao, Liangliang Song, Siyu Hao, Jing Yang, Yihao Zhou, Yunhao Xie, Peng Wu, Tong He, Yancai Wu, Robert B Petersen, Anlin Peng, Chun Zhang, Hong Chen, Ling Zheng, Kun Huang

Journal: SCIENCE ADVANCES

PubMed ID: 40315322

Doi: 10.1126/sciadv.adt3943

Products & Services: Peptide Synthesis