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Breaking the cancer code: a novel DNA minicircle to disable STAT3 in ovarian cancer cells SKOV3

Authors: Adina-Gabriela Vasilescu; Andrei-Mihai Vasilescu; Livia Elena Sima; Natalia Baran; tefan-Eugen Szedlacsek

Journal: Frontiers in pharmacology

PubMed ID: 41031165

Doi: 10.3389/fphar.2025.1673427

Breaking the cancer code: a novel DNA minicircle to disable STAT3 in ovarian cancer cells SKOV3

Authors: Adina-Gabriela Vasilescu; Andrei-Mihai Vasilescu; Livia Elena Sima; Natalia Baran; tefan-Eugen Szedlacsek

Journal: Frontiers in pharmacology

PubMed ID: 41031165

Doi: 10.3389/fphar.2025.1673427

Selective fluorination of Fc glycans enhances antibody-mediated effector functions

Authors: Xianyang Wang; Margaryta Gomozkova; Siqi Li; Biswarup Banerjee; Guanghui Zong; Dominique Missiakas; Lai-Xi Wang

Journal: Proceedings of the National Academy of Sciences of the United States of America

PubMed ID: 41849397

Doi: 10.1073/pnas.2530653123

Structural insights into the mechanism of activation and inhibition of the prostaglandin D2 receptor 1

Authors: Behnaz Davoudinasab, Aleksey Raskovalov, Woojin Lee, Donggyun Kim, Heesoo Kim, Jordy Homing Lam, Gye Won Han, Vsevolod Katritch, Vadim Cherezov

Journal: Nature Communications

PubMed ID: 41062467

Doi: 10.1038/s41467-025-64002-z

A motif preferred adenine base editor with minimal bystander and off-targets editing

Authors: Mengyu Shang, Yinuo Li, Qiuyu Cao, Jingxuan Ren, Yuqiang Zeng, Jinxin Wang, Rachel V. L. Gonzalez & Xiaohui Zhang

Journal: Nature Communications

PubMed ID: 41093849

Doi: 10.1038/s41467-025-64203-6

A dirigent protein redirects extracellular terpenoid metabolism for defense against biotic challenges

Authors: Jia-Ling Lin, Wen-Kai Wu, Gui-Bin Nie, Jian-Xu Li, Xin Fang, Yin-Guo Sheng, Meng-Meng Wang, Qi-Yue Zheng, Xiao-Xiang Guo, Jia-Fa Huang, Li-Ying Ma, Ling-Jian Wang, Jia-Xin Liu, Shan-Shan Wang, Baofu Xu, Yiqun Gao, Yan Li, Dong Wang, Cathie Martin, Xiao-Ya Chen & Jin-Quan Huang

Journal: Nature Communications

PubMed ID: 41115945

Doi: 10.1038/s41467-025-64323-z

Products & Services: Protein Electrophoresis and Western

Enteropathogenic bacteria evade ROCK-driven epithelial cell extrusion

Authors: Giovanni Luchetti, Marin V. Miner, Rachael M. Peterson, William P. Scott, Praveen Krishnamoorthy, Eric M. Kofoed, Angel G. Jimenez, Hua Zhang, Man Wah Tan, Rohit Reja, Tommy K. Cheung, Elizabeth Skippington, Yuxin Liang, Christopher M. Rose, Nobuhiko Kayagaki, Kim Newton, Isabella Rauch & Vishva M. Dixit

Journal: Nature

PubMed ID: 41125892

Doi: 10.1038/s41586-025-09645-0

Signal-strapping as a protein-sequence search method for the discovery of metalloproteins

Authors: João Paulo L Franco Cairo, Thamy L R Corrêa, Wendy A Offen, Alison K Nairn, Julia Walton, Sean T Sweeney, Gideon J Davies, Paul H Walton

Journal: Nature Communications

PubMed ID: 41115942

Doi: 10.1038/s41467-025-64309-x

Products & Services: Gene Synthesis PCR Cloning and Subcloning

Insights into next generation sequencing guided antibody selection strategies

Authors: M. Frank Erasmus; Fortunato Ferrara; Sara D Angelo; Laura Spector; Camila Leal-Lopes; Andr A. Teixeira; Jesper S rensen; Suhani Nagpal; Kathryn Perea-Schmittle; Alok Choudhary; William Honnen; David Calianese; Luis Antonio Rodriguez Carnero; Simon Cocklin; Victor Greiff; Abraham Pinter; Andrew R. M. Bradbury

Journal: Scientific REPORTS

PubMed ID: 37884618

Doi: 10.1038/s41598-023-45538-w

Products & Services: Catalog Antibodies

Rabies virus-vectored Lyme disease vaccine provides long-term protection against tick-transmitted Borrelia burgdorferi

Authors: Shantel Rios; Bibek Bhattachan; Christoph Wirblich; Anisha Chandwani; Kruthi Vavilikolanu; Jacob F. Myers; Chrysoula Kitsou; Utpal Pal; Matthias J. Schnell

Journal: npj Vaccines

PubMed ID: 41233361

Doi: 10.1038/s41541-025-01294-8