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The Sobering Sting: Oleoyl Serotonin Is a Novel Stephanoconus Snail Venom-Derived Antagonist of Cannabinoid Receptors That Counteracts Learning and Memory Deficits

Authors: Dongchen An; Guilherme Salgado Carrazoni; Ben-Hur Souto das Neves; Rudi D Hooge; Steve Peigneur; Jan Tytgat

Journal: Biomedicines

PubMed ID: 38398056

Doi: 10.3390/biomedicines12020454

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In vitro characterization of the catalytic domain of human histone deacetylase 5

Authors: Christian Mammen; Fenja M. Hornung; Christian Anzenhofer; Julia Schumacher; Jens Reiners; Jingyu Li; Flaminia Mazzone; Florestan L. Bilsing; Matthias U. Kassack; Thomas Kurz; Sander H. J. Smits

Journal: Scientific REPORTS

PubMed ID: 41760657

Doi: 10.1038/s41598-026-37633-5

Torsional Twist of the SARS-CoV and SARS-CoV-2 SUD-N and SUD-M domains

Authors: Monica Rosas-Lemus; George Minasov; Joseph S. Brunzelle; Taha Y. Taha; Sofia Lemak; Shaohui Yin; Ludmilla Shuvalova; Julia Rosecrans; Kanika Khanna; H Steven Seifert; Alexei Savchenko; Peter J. Stogios; Melanie Ott; Karla J. F. Satchell

Journal: biorxiv

PubMed ID: 39185168

Doi: 10.1101/2024.08.13.607777

Enabling Open Machine Learning of Deoxyribonucleic Acid-Encoded Library Selections to Accelerate the Discovery of Small Molecule Protein Binders

Authors: James Wellnitz; Shabbir Ahmad; Nabin Bagale; Xuemin Cheng; Jermiah Joseph; Hong Zeng; Albina Bolotokova; Aiping Dong; Shaghayegh Reza; Pegah Ghiabi; Elisa Gibson; Guiping Tu; Xianyang Li; Jian Liu; Dengfeng Dou; Jin Li; Timothy L. Foley; Anthony R. Harris; Jacquelyn L. Klug-McLeod; Jisun Lee; Zsofia Lengyel-Zhand; Justin I. Montgomery; Sylvie Sakata; Jinzhi Zhang; Hongyao Zhu; Dafydd R. Owen; Rachel J. Harding; Aled M. Edwards; Benjamin Haibe-Kains; Levon Halabelian; Alexander Tropsha; Rafael M. Cou ago

Journal: Journal of Medicinal Chemistry

PubMed ID: 41047897

Doi: 10.1021/acs.jmedchem.5c01972

Products & Services: Protein and Antibody Isolation

Insights into next generation sequencing guided antibody selection strategies

Authors: M. Frank Erasmus; Fortunato Ferrara; Sara D Angelo; Laura Spector; Camila Leal-Lopes; Andr A. Teixeira; Jesper S rensen; Suhani Nagpal; Kathryn Perea-Schmittle; Alok Choudhary; William Honnen; David Calianese; Luis Antonio Rodriguez Carnero; Simon Cocklin; Victor Greiff; Abraham Pinter; Andrew R. M. Bradbury

Journal: Scientific REPORTS

PubMed ID: 37884618

Doi: 10.1038/s41598-023-45538-w

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Rabies virus-vectored Lyme disease vaccine provides long-term protection against tick-transmitted Borrelia burgdorferi

Authors: Shantel Rios; Bibek Bhattachan; Christoph Wirblich; Anisha Chandwani; Kruthi Vavilikolanu; Jacob F. Myers; Chrysoula Kitsou; Utpal Pal; Matthias J. Schnell

Journal: npj Vaccines

PubMed ID: 41233361

Doi: 10.1038/s41541-025-01294-8

De novo designed voltage-gated anion channels suppress neuron firing

Authors: Chen Zhou, Huican Li, Jiaxing Wang, Cheng Qian, Hui Xiong, Zhilin Chu, Qiming Shao, Xuan Li, Shijin Sun, Ke Sun, Aiqin Zhu, Jiawei Wang, Xueqin Jin, Fan Yang, Tamer M Gamal El-Din, Bo Li, Jing Huang, Kun Wu, Peilong Lu

Journal: Cell

PubMed ID: 41106381

Doi: 10.1016/j.cell.2025.09.023

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A novel low-cost and sensitive electrochemical biosensor based on Yb-protein/GO/SPE for rare earth element detection

Authors: Ting Zhang, Danni Ma, Jiaxing Gong, Bolun Sun, Fuman Cai

Journal: Sustainable Chemistry and Pharmacy

Doi: doi.org/10.1016/j.scp.2025.102248

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Arzanol Inhibits Human Dihydroorotate Dehydrogenase and Shows Antiviral Activity

Authors: Marta Alberti, Martina Tamburello, Stefano Salamone, Giorgio Gallinella, Cinzia Sanna, Giovanni Battista Appendino, Marco L Lolli, Alberto Massarotti, Federica Pollastro, Riccardo Miggiano

Journal: Journal of natural products

PubMed ID: 41143446

Doi: 10.1021/acs.jnatprod.5c00887

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Simultaneous Monitoring of Intracellular Glucose and Extracellular Lactate in Single Cells to Assess Cell Tumorigenicity

Authors: Hui Liu, Yu Liu, Songqin Liu, Yafeng Wu

Journal: Analytical Chemistry

PubMed ID: 41035132

Doi: 10.1021/acs.analchem.5c03740

Products & Services: Recombinant Proteins