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Enhanced immunogenicity of a positively supercharged archaeon thioredoxin scaffold as a cell-penetrating antigen carrier for peptide vaccines

Authors: Davide Cavazzini, Gloria Spagnoli, Filipe Colaco Mariz, Filippo Reggiani, Stefano Maggi, Valentina Franceschi, Gaetano Donofrio, Martin Müller, Angelo Bolchi, Simone Ottonello

Journal: Front Immunol

PubMed ID: 36032169

Doi: 10.3389/fimmu.2022.958123

Products & Services: Catalog Peptides

Low pH structure of heliorhodopsin reveals chloride binding site and intramolecular signaling pathway

Authors: Jessica E Besaw, Jörg Reichenwallner, Paolo De Guzman, Andrejs Tucs, Anling Kuo, Takefumi Morizumi, Koji Tsuda, Adnan Sljoka, R J Dwayne Miller, Oliver P Ernst

Journal: Sci Rep

PubMed ID: 35977989

Doi: 10.1038/s41598-022-17716-9

Products & Services: Custom Vector Construction

Mechanistic insights into global suppressors of protein folding defects

Authors: Gopinath Chattopadhyay, Jayantika Bhowmick, Kavyashree Manjunath, Shahbaz Ahmed, Parveen Goyal, Raghavan Varadarajan

Journal: PLoS Genet

PubMed ID: 36037221

Doi: 10.1371/journal.pgen.1010334

Products & Services: Proteins, Expression, Isolation and Analysis

Refolding and characterization of a diabody against Pfs25, a vaccine candidate of Plasmodium falciparum

Authors: Deepak K Jagannath, Ashwathi Valiyaparambil, Vysakh K Viswanath, Manjunath A Hurakadli, Neelagandan Kamariah, Alifia C Jafer, Chhaya Patole, Sabyasachi Pradhan, Naveen Kumar, Anirudha Lakshminarasimhan

Journal: Anal Biochem

PubMed ID: 35944694

Doi: 10.1016/j.ab.2022.114830

Products & Services: PCR Cloning and Subcloning

Generation of hepatoma cell lines deficient in microsomal triglyceride transfer protein

Authors: Narasimha Anaganti, Atrayee Chattopadhyay, John T Poirier, M Mahmood Hussain

Journal: J Lipid Res

PubMed ID: 35931202

Doi: 10.1016/j.jlr.2022.100257

Products & Services: Catalog Peptides

Knockdown of HSP110 attenuates hypoxia-induced pulmonary hypertension in mice through suppression of YAP/TAZ-TEAD4 pathway

Authors: Haitao Liu, Sha Zhang, Yi Liu, Jing Ma, Wei Chen, Tao Yin, Tongbin Li, Bin Liang, Ling Tao

Journal: Respir Res

PubMed ID: 35986277

Doi: 10.1186/s12931-022-02124-4

Products & Services: Plasmid DNA Preparation

Tumor-infiltrated activated B cells suppress liver metastasis of colorectal cancers

Authors: Yuqiu Xu, Zhuang Wei, Mei Feng, Dexiang Zhu, Shenglin Mei, Zhongen Wu, Qingyang Feng, Wenju Chang, Meiling Ji, Chenglong Liu, Yuanyuan Zhu, Lian Shen, Fan Yang, Yijiao Chen, Yuxiong Feng, Jianmin Xu, Di Zhu

Journal: Cell Rep

PubMed ID: 36044847

Doi: 10.1016/j.celrep.2022.111295

Products & Services: Recombinant Proteins

Post-translational control of beige fat biogenesis by PRDM16 stabilization

Authors: Qiang Wang, Huixia Li, Kazuki Tajima, Anthony R P Verkerke, Zachary H Taxin, Zhishuai Hou, Joanne B Cole, Fei Li, Jake Wong, Ichitaro Abe, Rachana N Pradhan, Tadashi Yamamuro, Takeshi Yoneshiro, Joel N Hirschhorn, Shingo Kajimura

Journal: Nature

PubMed ID: 35978186

Doi: 10.1038/s41586-022-05067-4

Products & Services: Custom DNA/RNA Oligos

Oxidized low-density lipoprotein receptor 1: a novel potential therapeutic target for intracerebral hemorrhage

Authors: Hui-Yuan Zhang, Xi Lu, Yue-Han Hao, Ling Tang, Zhi-Yi He

Journal: Neural Regen Res

PubMed ID: 35017440

Doi: 10.4103/1673-5374.332157

Products & Services: Gene Synthesis

Targeted Carbon Nanostructures for Chemical and Gene Delivery to Plant Chloroplasts

Authors: Israel Santana, Su-Ji Jeon, Hye-In Kim, Md Reyazul Islam, Christopher Castillo, Gail F H Garcia, Gregory M Newkirk, Juan Pablo Giraldo

Journal: ACS Nano

PubMed ID: 35943045

Doi: 10.1021/acsnano.2c02714

Products & Services: Molecular Biology Reagents

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