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High-throughput investigation of cyclin docking interactions reveals the complexity of motif binding determinants

Authors: Mihkel Örd, Matthew J Winters, Mythili S Subbanna, Natàlia de Martín Garrido, Victoria I Cushing, Johanna Kliche, Caroline Benz, Ylva Ivarsson, Basil J Greber, Peter M Pryciak, Norman E Davey

Journal: Nature Communications

PubMed ID: 40817109

Doi: 10.1038/s41467-025-62765-z.

Products & Services: Peptide Synthesis

POSTN-Mediated Interplay of M1 Polarized Macrophage with Tendon-Derived Stem Cells to Drive Traumatic Heterotopic Ossification Formation through PTK7/ATK Signaling?

Authors: Hang Liu, Xinyue Li, Mengyi Li, Ziyang Sun, Xu Wang, Juehong Li, Binbin Xu, Qian Chen, Cunyi Fan, Hongjiang Ruan

Journal: Advanced Science

PubMed ID: 40823759

Doi: 10.1002/advs.202507951

Products & Services: Custom Vector Construction

HIV broadly neutralizing antibody precursors to the Apex epitope induced in nonhuman primates

Authors: Krystal M Ma, Henry J Sutton, Payal P Pratap, Jon M Steichen, Diane Carnathan, James Quinn, Oleksandr Kalyuzhniy, Alessia Liguori, Sashank Agrawal, Sabyasachi Baboo, Patrick Madden, Christopher A Cottrell, Jordan R Willis, Jeong-Hyun Lee, Elise Landais, Xiaozhen Hu, Parham Ramezani-Rad, Gabriel Ozorowski, Vanessa R Lewis, Jolene K Diedrich, Xiaoya Zhou, Tasha K Altheide, Nicole Phelps, Erik Georgeson, Nushin B Alavi, Danny Lu, Saman Eskandarzadeh, Michael Kubitz, Yumiko Adachi, Tina-Marie Mullen, Murillo Silva, Mariane B Melo, Sunny Himansu, Darrell J Irvine, Dennis R Burton, John R Yates 3rd, James C Paulson, Devin Sok, Ian A Wilson, Guido Silvestri, Andrew B Ward, Shane

Journal: Science immunology

PubMed ID: 40845127

Doi: 10.1126/sciimmunol.adt6660

Products & Services: Recombinant Antibody Expression

Discovery of CRISPR-Cas12a clades using a large language model

Authors: Yuanyuan Feng, Junchao Shi, Zhanwei Li, Yongqian Li, Jiaxi Yang, Shisheng Huang, Jinfang Zheng, Wei Han, Yunbo Qiao, Jun Zhang, Qi Liu, Yao Yang, Chunyi Hu, Lina Wu, Xiaokang Zhang, Jin Tang, Xingxu Huang, Peixiang Ma

Journal: Nature Communications

PubMed ID: 40849498

Doi: 10.1038/s41467-025-63160-4.

Products & Services: Synthetic Guide RNA

DeFrND: detergent-free reconstitution into native nanodiscs with designer membrane scaffold peptides

Authors: Qian Ren, Jing Wang, Vinay Idikuda, Shanwen Zhang, Jeehae Shin, W Grant Ludlam, Luis M Real Hernandez, Sara Zdancewicz, Alex J B Kreutzberger, Hucheng Chang, Volker Kiessling, Lukas K Tamm, Ahmad Jomaa, Ilya Levental, Kirill Martemyanov, Baron Chanda, Huan Bao, Dhanya Thamaraparambil Jayaram, Pranav Sivaram, Pranjal Biswas, Yue Dai, Elizabeth A Sweeny, Dennis J Stuehr

Journal: Nature Communications

PubMed ID: 40858559

Doi: 10.1038/s41467-025-63275-8.

Products & Services: Protein and Antibody Isolation

USP17L promotes the 2-cell-like program through deubiquitination of H2AK119ub1 and ZSCAN4

Authors: Panpan Shi, Xukun Lu, Kairang Jin, Linlin Liu, Guoxing Yin, Wenying Wang, Jiao Yang, Lijuan Wang, Lijun Dong, Wei Xie, Lin Liu

Journal: Nature Communications

PubMed ID: 40750602

Doi: 10.1038/s41467-025-62303-x.

Products & Services: Polyclonal Antibody Services

GTP hydrolysis triggers membrane remodeling by AMPH-1

Authors: Wei Gai https://orcid.org/0009-0005-5681-7380, Yuhang Wang https://orcid.org/0000-0002-8048-138X, Brianna Martin, Junjie Zhang https://orcid.org/0000-0002-7912-0819, Chavela M. Carr https://orcid.org/0009-0005-1292-1119, and Hays S. Rye

Journal: SCIENCE ADVANCES

PubMed ID: 40749062

Doi: 10.1126/sciadv.ads9443

Products & Services: Protein and Antibody Isolation

The EMC acts as a chaperone for membrane proteins

Authors: Carolin J Klose, Kevin M Meighen-Berger, Martin Kulke, Marina Parr, Barbara Steigenberger, Martin Zacharias, Dmitrij Frishman, Matthias J Feige

Journal: Nature Communications

PubMed ID: 40753078

Doi: 10.1038/s41467-025-62109-x

Products & Services: Catalog Antibodies

Lung metastasis and recurrence is mitigated by CARmacrophages, in-situ-generated from mRNA delivered by small extracellular vesicles

Authors: Yuchen Xiao, Tianchuan Zhu, Zhenxing Chen, Xi Huang

Journal: Nature Communications

PubMed ID: 40759657

Doi: 10.1038/s41467-025-62506-2

Products & Services: Custom DNA/RNA Oligos

Exomeres From Adventitial Fibroblasts of Spontaneously Hypertensive Rats Promote Vascular Remodelling via Transferring Osteopontin.

Authors: Jing-Xiao Wang, Xiao-Yu Xu, Hong-Ke Dong, Yi-Ming Wang, Min Dai, Bing Zhou, Yue-Hua Li, Guo-Qing Zhu, Xiao-Qing Xiong

Journal: Journal of extracellular vesicles

PubMed ID: 40767027

Doi: 10.1002/jev2.70146.

Products & Services: Custom RNAi Services