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Unambiguous discrimination of all 20 proteinogenic amino acids and their modifications by nanopore

Authors: Kefan Wang, Shanyu Zhang, Xiao Zhou, Xian Yang, Xinyue Li, Yuqin Wang, Pingping Fan, Yunqi Xiao, Wen Sun, Panke Zhang, Wenfei Li, Shuo Huang

Journal: Nat Methods

PubMed ID: 37749214

Doi: 10.1038/s41592-023-02021-8

Products & Services: Protein and Antibody Isolation

Tau fibrils induce glial inflammation and neuropathology via TLR2 in Alzheimer's disease-related mouse models

Authors: Debashis Dutta, Malabendu Jana, Ramesh Kumar Paidi, Moumita Majumder, Sumita Raha, Sridevi Dasarathy, Kalipada Pahan

Journal: J Clin Invest

PubMed ID: 37552543

Doi: 10.1172/JCI161987

Products & Services: Protein and Antibody Isolation

A mechanism that ensures non-selective cytoplasm degradation by autophagy

Authors: Tetsuya Kotani, Yuji Sakai, Hiromi Kirisako, Chika Kakuta, Soichiro Kakuta, Yoshinori Ohsumi, Hitoshi Nakatogawa

Journal: Nat Commun

PubMed ID: 37726301

Doi: 10.1038/s41467-023-41525-x

Products & Services: Gene Synthesis

A computationally designed antigen eliciting broad humoral responses against SARS-CoV-2 and related sarbecoviruses

Authors: Sneha Vishwanath, George William Carnell, Matteo Ferrari, Benedikt Asbach, Martina Billmeier, Charlotte George, Maria Suau Sans, Angalee Nadesalingam, Chloe Qingzhou Huang, Minna Paloniemi, Hazel Stewart, Andrew Chan, David Arthur Wells, Patrick Neckermann, David Peterhoff, Sebastian Einhauser, Diego Cantoni, Martin Mayora Neto, Ingo Jordan, Volker Sandig, Paul Tonks, Nigel Temperton, Simon Frost, Katharina Sohr, Maria Teresa Lluesma Ballesteros, Farzad Arbabi, Johannes Geiger, Christian Dohmen, Christian Plank, Rebecca Kinsley, Ralf Wagner, Jonathan Luke Heeney

Journal: Nat Biomed Eng

PubMed ID: 37749309

Doi: 10.1038/s41551-023-01094-2

Products & Services: Protein and Antibody Isolation

Deep mutational scanning and machine learning uncover antimicrobial peptide features driving membrane selectivity

Authors: Justin R. Randall; Luiz C. Vieira; Claus O. Wilke; Bryan W. Davies

Journal: biorxiv

PubMed ID: 37547010

Doi: 10.1101/2023.07.28.551017

Products & Services: Peptide Synthesis

The cryo-EM-delineated mechanism underlying mimicry of CXCR4 agonism enables widespread stem cell neuroprotection in a mouse model of ALS

Authors: Xiaohong Sang; Haizhan Jiao; Qian Meng; Xiong Fang; Kartik S. Sundaram; Jiao Zhou; Yan Xu; Asuka I. W. Alvarado; Ruslan L. Nuryyev; Jitka Ourenik; Vaclav Ourednik; Iris S. Huang; Xiang Liu; Yuheng Mei; Tingli Qian; Aaron Ciechanover; Donald P. Pizzo; Michael A. Lane; Lyandysha V. Zholudeva; Jing An; Evan Y. Snyder; Hongli Hu; Ziwei Huang

Journal: biorxiv

PubMed ID: 40672153

Doi: 10.1101/2025.07.08.663251

Products & Services: Protein and Antibody Isolation

Coordinated regulation by lncRNAs results in tight lncRNA-target couplings

Authors: Hua-Sheng Chiu; Sonal Somvanshi; Chung-Te Chang; Eric James de Bony de Lavergne; Zhaowen Wei; Chih-Hung Hsieh; Wim Trypsteen; Kathleen A. Scorsone; Ektaben Patel; Tien T. Tang; David B. Flint; Mohammad Javad Najaf Panah; Hyunjae Ryan Kim; Purva Rathi; Yan-Hwa Wu Lee; Sarah E. Woodfield; Sanjeev A. Vasudevan; Andras Attila Heczey; M. Waleed Gaber; Gabriel O. Sawakuchi; Ting-Wen Chen; Pieter Mestdagh; Xuerui Yang; Pavel Sumazin

Journal: Cell Genomics

PubMed ID: 40628267

Doi: 10.1016/j.xgen.2025.100927

Coordinated regulation by lncRNAs results in tight lncRNA-target couplings

Journal: Cell Genomics

PubMed ID: 40628267

Doi: 10.1016/j.xgen.2025.100927

Novel In Silico mRNA vaccine design exploiting proteins of M. tuberculosis that modulates host immune responses by inducing epigenetic modifications

Authors: H. Al Tbeishat

Journal: Scientific REPORTS

PubMed ID: 35301360

Doi: 10.1038/s41598-022-08506-4

Products & Services: Codon Optimization

CRISPR-ChIP reveals selective regulation of H3K79me2 by Menin in MLL leukemia

Authors: Omer Gilan, Laure Talarmain, Charles C Bell, Daniel Neville, Kathy Knezevic, Daniel T Ferguson, Marion Boudes, Yih-Chih Chan, Chen Davidovich, Enid Y N Lam, Mark A Dawson

Journal: Nat Struct Mol Biol

PubMed ID: 37679565

Doi: 10.1038/s41594-023-01087-4

Products & Services: Protein and Antibody Isolation