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Supramolecular lipid nanoparticle reprograms tumor microenvironment by cucurbit[7]uril-based host–guest recognition for STING-activating cancer immunotherapy

Authors: Yunxuan Feng, Yuan Yu, Xinyang Yu, Mengyao Li, Jiaqi Lei, Yongcan Li, Zhida Liu, Shaolong Qi, Guocan Yu

Journal: Materials Today

Doi: doi.org/10.1016/j.mattod.2025.11.029

Products & Services: Protein Electrophoresis and Western

OMP16-targeting monoclonal antibodies H4 and E6 reveal essential linear epitopes for Brucella immunoprotection

Authors: Yunyi Zhai, Kaihui Sun, Ye Yuan, Xiaofang Liu, Gaowa Wudong, Yuanhao Yang, Shuan Qu, Yaxin Li, Dong Zhou, Wei Liu, Yaping Jin, Aihua Wang

Journal: International Journal of Biological Macromolecules

PubMed ID: 41448303

Doi: 10.1016/j.ijbiomac.2025.149881

Products & Services: Bacterial Expression Mutagenesis Services Peptide Synthesis

Study on the phosphorylation of NAD+-specific isocitrate dehydrogenase in the pathogenic bacteria Stenotrophomonas maltophilia and Xanthomonas sacchari

Authors: Qian Tian, Yongmei Zhang, Chunxu Pan, Linxiao Wang, Na Qin, Zhen Jiang, Chenxi Li, Zhengyu Cao, Guoping Zhu, Peng Wang

Journal: Journal of enzyme inhibition and medicinal chemistry

PubMed ID: 41395810

Doi: 10.1080/14756366.2025.2593798

Products & Services: Gene Synthesis Codon Optimization

The ATPase activity of ABCB10 is modulated by conserved transmembrane arginine residues and by functional groups in the biliverdin molecule

Authors: Annabella Nouel Barreto, Valeria Arellano Haro, Alex L Hernandez, Maria E Zoghbi

Journal: Protein Science

PubMed ID: 41229075

Doi: 10.1002/pro.70366

Products & Services: Gene Synthesis Mutagenesis Services

Design of precision therapeutics for a CKD risk allele by targeting Shroom3-Rock interaction

Authors: Anand Reghuvaran; Ashwani Kumar; Qisheng Lin; Nallakandi Rajeevan; Khadija Banu; Zeguo Sun; Hongmei Shi; Gabriel Barsotti; EM Tanvir; John Pell; Sudhir Perincheri; Chengguo Wei; Bhavya Bharathan; Marina Planoutene; Anne Eichmann; Valeria Mas; Weijia Zhang; Lloyd G. Cantley; Leyuan Xu; Bhaskar Das; John Cijiang He; Madhav C. Menon

Journal: Nature Communications

PubMed ID: 41469391

Doi: 10.1038/s41467-025-67854-7

Structural basis of Neisseria meningitidis quinol dependent nitric oxide reductase activation by dimerization

Authors: Chai C. Gopalasingam; Haruka Egami; Hideki Shigematsu; Masatora Sakaue; Kouki Fukumoto; Christoph Gerle; Masaki Yamamoto; Yoshitsugu Shiro; Kazumasa Muramoto; Takehiko Tosha

Journal: Communications Biology

PubMed ID: 41896389

Doi: 10.1038/s42003-026-09754-0

Products & Services: Plasmid DNA Preparation

First inhibitor of a bacterial two-partner secretion system

Authors: Alfred Hartojo; Laurence Don Wai Luu; Lachlan Adamson; Kyra Majors; Ashleigh S. Paparella; Peggy A. Cotter; Richard M. Johnson; Matthew Thomas Doyle

Journal: biorxiv

PubMed ID: 41648283

Doi: 10.64898/2026.01.11.698920

Immune activation of the host cell induces drug tolerance in Mycobacterium tuberculosis both in vitro and in vivo

Authors: Yancheng Liu; Shumin Tan; Lu Huang; Robert B. Abramovitch; Kyle H. Rohde; Matthew D. Zimmerman; Chao Chen; V ronique Dartois; Brian C. VanderVen; David G. Russell

Journal: The Journal of experimental medicine

PubMed ID: 27114608

Doi: 10.1084/jem.20151248

Products & Services: Endotoxin Detection & Removal System

Targeting Protein Protein Interactions (PPIs) to Drive Functional Annotation: An Integrative Methodology to Study Senescence-Associated PPIs Using TMPRSS11a as Model Interactor

Authors: Roberto Rosales-Rojas; Christian Fern ndez; Mariela Gonz lez-Avenda o; Ariela Vergara-Jaque; M nica C ceres

Journal: Biomolecules

PubMed ID: 42194062

Doi: 10.3390/biom16050714