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页码: 332/5131 每页显示数量
Deep learning models to predict the editing efficiencies and outcomes of diverse base editors
Authors: Nahye Kim, Sungchul Choi, Sungjae Kim, Myungjae Song, Jung Hwa Seo, Seonwoo Min, Jinman Park, Sung-Rae Cho, Hyongbum Henry Kim
Journal: Nat Biotechnol
PubMed ID: 37188916
Doi: 10.1038/s41587-023-01792-x
Products & Services: Gene Synthesis   
Structure of a 10-23 Deoxyribozyme Exhibiting a Homodimer Conformation
Authors: Evan Cramer, Sarah Starcovic, Rebekah Avey, Ali Kaya, Aaron Robart
Journal: Res Sq
PubMed ID: 37398199
Doi: 10.21203/rs.3.rs-2252941/v1
Products & Services: Gene Synthesis   
Engineering Rapalog-Inducible Genetic Switches Based on Split-T7 Polymerase to Regulate Oncolytic Virus-Driven Production of Tumour-Localized IL-12 for Anti-Cancer Immunotherapy
Authors: Nikolas T Martin, Mathieu J F Crupi, Zaid Taha, Joanna Poutou, Jack T Whelan, Sydney Vallati, Julia Petryk, Ricardo Marius, Bradley Austin, Taha Azad, Mason Boulanger, Tamara Burgess, Ilson Sanders, Camille Victoor, Bryan C Dickinson, Jean-Simon Diallo, Carolina S Ilkow, John C Bell
Journal: Pharmaceuticals (Basel)
PubMed ID: 37242495
Doi: 10.3390/ph16050709
Products & Services: Recombinant Proteins   
Evaluation of humoral and cellular immune responses induced by a cocktail of recombinant African swine fever virus antigens fused with OprI in domestic pigs
Authors: Guanglei Zhang, Wei Liu, Sicheng Yang, Shuai Song, Yunyun Ma, Guangqing Zhou, Xiaxia Liang, Chun Miao, Junhui Li, Yanhong Liu, Junjun Shao, Huiyun Chang
Journal: Virol J
PubMed ID: 37237390
Doi: 10.1186/s12985-023-02070-7
Products & Services: DNA Sequencing   
Design and development of microformulations for rapid release of small molecules and oligonucleotides
Authors: T Brown, M Stanton, F Cros, S Cho, A Kiselyov
Journal: Eur J Pharm Sci
PubMed ID: 37220816
Doi: 10.1016/j.ejps.2023.106472
Enhanced stability of the SARS CoV-2 spike glycoprotein following modification of an alanine cavity in the protein core
Authors: Pantelis Poumbourios, Christine Langer, Irene Boo, Tasnim Zakir, Rob J Center, Anouschka Akerman, Vanessa Milogiannakis, Anupriya Aggarwal, Bronte A Johnstone, Jungmin Ha, Fasséli Coulibaly, Stuart G Turville, Heidi E Drummer
Journal: PLoS Pathog
PubMed ID: 37200378
Doi: 10.1371/journal.ppat.1010981
Rescue of secretion of a rare-disease associated mis-folded mutant glycoprotein in knock-out mammalian cells
Authors: Gábor Tax, Kevin P Guay, Tatiana Soldà, Charlie J Hitchman, Johan C Hill, Snežana Vasiljević, Andrea Lia, Carlos P Modenutti, Kees R Straatman, Angelo Santino, Maurizio Molinari, Nicole Zitzmann, Daniel N Hebert, Pietro Roversi, Marco Trerotola
Journal: biorxiv
PubMed ID: 37398215
Doi: 10.1101/2023.05.30.542711
The E3 Ubiquitin Ligase SCF Cyclin F Promotes Sequestosome-1/p62 Insolubility and Foci Formation and is Dysregulated in ALS and FTD Pathogenesis
Authors: Jennilee M Davidson, Sharlynn S L Wu, Stephanie L Rayner, Flora Cheng, Kimberley Duncan, Carlo Russo, Michelle Newbery, Kunjie Ding, Natalie M Scherer, Rachelle Balez, Alberto García-Redondo, Alberto Rábano, Livia Rosa-Fernandes, Lezanne Ooi, Kelly L Williams, Marco Morsch, Ian P Blair, Antonio Di Ieva, Shu Yang, Roger S Chung, Albert Lee
Journal: Mol Neurobiol
PubMed ID: 37243816
Doi: 10.1007/s12035-023-03355-2
saRNA vaccine expressing membrane-anchored RBD elicits broad and durable immunity against SARS-CoV-2 variants of concern
Authors: Mai Komori, Takuto Nogimori, Amber L Morey, Takashi Sekida, Keiko Ishimoto, Matthew R Hassett, Yuji Masuta, Hirotaka Ode, Tomokazu Tamura, Rigel Suzuki, Jeff Alexander, Yasutoshi Kido, Kenta Matsuda, Takasuke Fukuhara, Yasumasa Iwatani, Takuya Yamamoto, Jonathan F Smith, Wataru Akahata
Journal: Nat Commun
PubMed ID: 37208330
Doi: 10.1038/s41467-023-38457-x
Fusion of the molecular adjuvant C3d to cleavage-independent native-like HIV-1 Env trimers improves the elicited antibody response
Authors: Shridhar Bale, Lifei Yang, Mehrdad Alirezaei, Richard Wilson, Takayuki Ota, Esmeralda D Doyle, Christopher A Cottrell, Javier Guenaga, Karen Tran, Wenjuan Li, Leonidas Stamatatos, David Nemazee, Andrew B Ward, Richard T Wyatt
Journal: Front Immunol
PubMed ID: 37283743
Doi: 10.3389/fimmu.2023.1180959

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