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Expanding the druggable zinc-finger proteome defines properties of drug-induced degradation

Authors: Miko aj S abicki; Jiho Park; Rados aw P. Nowak; Shourya S. Roy Burman; Jesse Pellman; Charles Zou; Hlib Razumkov; Jeannie Carreiro; Simran Rastogi; Anna Goldstein; Marek M. Nagiec; Katherine A. Donovan; Jianwei Che; Moritz Hunkeler; Qixiang Geng; Chi-Lin Hsu; Megha Lakshminarayan; Chelsea Shu; Rebecca L. Zon; Zuzanna Kozicka; Paul M.C. Park; Jonathan M. Tsai; Hojong Yoon; Lyn H. Jones; Adam S. Sperling; Nathanael S. Gray; Eric S. Fischer; Benjamin L. Ebert

Journal: Molecular Cell

PubMed ID: 40845806

Doi: 10.1016/j.molcel.2025.07.019

Decoding the blueprint of receptor binding by filoviruses through large-scale binding assays and machine learning

Authors: Gorka Lasso; Michael Grodus; Estefania Valencia; Veronica DeJesus; Eliza Liang; Isabel Delwel; Rob H. Bortz; Dmitry Lupyan; Hanna Y. Ehrlich; Adrian A. Castellanos; Andrea Gazzo; Heather L. Wells; Supaporn Wacharapluesadee; Alexandre Tremeau-Bravard; Janine F.R. Seetahal; Tom Hughes; Jimmy Lee; Mei-Ho Lee; Anna R. Sjodin; Marike Geldenhuys; Marinda Mortlock; Isamara Navarrete-Macias; Kirsten Gilardi; Michael R. Willig; Alessandra F.D. Nava; Elisabeth H. Loh; Makda Asrat; Tierra Smiley-Evans; Walter S. Magesa; Sijali Zikankuba; David Wolking; Gerardo Suz n; Rafael Ojeda-Flores; Christine V.F. Carrington; Ariful Islam; Jonathan H. Epstein; Wanda Markotter; Christine K. Johnson; Tracey Goldstein; Barbara A. Han; Jonna A.K. Mazet; Rohit K. Jangra; Kartik Chandran; Simon J. Anthony

Journal: Cell Host & Microbe

PubMed ID: 39818205

Doi: 10.1016/j.chom.2024.12.016

Products & Services: Protein and Antibody Isolation

Virtual screening and evaluation of bioactive peptides from Haliotis discus hannai as potential HMGCR inhibitors for hyperlipidemia treatment

Authors: Kun Qiao; Lina Liu; Yihui Chen; Qiongmei Huang; Bei Chen; Jingna Wu; Wenmei Huang; Zhiyu Liu

Journal: Frontiers in nutrition

PubMed ID: 39811675

Doi: 10.3389/fnut.2024.1525768

Products & Services: Peptide Synthesis

Duration of antibody response to the receptor binding domain of SARS-CoV-2 in infected or vaccinated individuals - A one year retrospective cohort study

Authors: Martin Pasev, Angelina Trifonova, Andrey Velichkov, Velislava Terzieva

Journal: Int Immunopharmacol

PubMed ID: 38621337

Doi: 10.1016/j.intimp.2024.112084

Products & Services: Serology SARS-Cov-2 detection kits

A long-acting FGF21 attenuates metabolic dysfunction-associated steatohepatitis-related fibrosis by modulating NR4A1-mediated Ly6C phenotypic switch in macrophages

Authors: Yue Ji, Yiliang Duan, Yuanyuan Li, Qingzhou Lu, Dingkang Liu, Yifan Yang, Ruilong Chang, Jing Tian, Wenbing Yao, Jun Yin, Xiangdong Gao

Journal: Br J Pharmacol

PubMed ID: 38679486

Doi: 10.1111/bph.16378

Products & Services: Molecular Biology Reagents

Crosstalk interactions between transcription factors ERRα and PPARα assist PPARα-mediated gene expression

Authors: Sofie J Desmet, Jonathan Thommis, Tineke Vanderhaeghen, Edmee M F Vandenboorn, Dorien Clarisse, Yunkun Li, Steven Timmermans, Daria Fijalkowska, Dariusz Ratman, Evelien Van Hamme, Lode De Cauwer, Bart Staels, Luc Brunsveld, Frank Peelman, Claude Libert, Jan Tavernier, Karolien De Bosscher

Journal: Mol Metab

PubMed ID: 38631478

Doi: 10.1016/j.molmet.2024.101938

Products & Services: Molecular Biology Reagents

HLA-C*04:09N is expressed at the cell surface and triggers peptide-specific T-cell activation

Authors: Carlotta Welters, Marthe-Lina Welters, Serena Stadler, Lars Bullinger, Julian Strobel, Holger Hackstein, Arunraj Dhamodaran, Thomas Blankenstein, Leo Hansmann

Journal: Haematologica

PubMed ID: 37767552

Doi: 10.3324/haematol.2023.283812

Products & Services: Catalog Peptides

Synthetic Peptides Selected by Immunoinformatics as Potential Tools for the Specific Diagnosis of Canine Visceral Leishmaniasis

Authors: Gabriel Moreira, Rodrigo Maia, Nathália Soares, Thais Ostolin, Wendel Coura-Vital, Rodrigo Aguiar-Soares, Jeronimo Ruiz, Daniela Resende, Rory de Brito, Alexandre Reis, Bruno Roatt

Journal: Microorganisms

PubMed ID: 38792746

Doi: 10.3390/microorganisms12050906

Products & Services: Catalog Peptides

Quantitation of Enterovirus A71 Empty and Full Particles by Sedimentation Velocity Analytical Ultracentrifugation

Authors: Anna Yang, Yun Luo, Jie Yang, Tingbo Xie, Wenhui Wang, Xin Wan, Kaiwen Wang, Deqin Pang, Dongsheng Yang, Hanyu Dai, Jie Wu, Shengli Meng, Jing Guo, Zejun Wang, Shuo Shen

Journal: Viruses

PubMed ID: 38675915

Doi: 10.3390/v16040573

Products & Services: Protein Electrophoresis and Western

Identification of PEX5-PTS1 Interaction Inhibitors through Fluorescence Polarization-Based High-Throughput Screening

Authors: Trong-Nhat Phan, Kyu-Ho Paul Park, David Shum, Joo Hwan No

Journal: Molecules

PubMed ID: 38675653

Doi: 10.3390/molecules29081835

Products & Services: Molecular Biology Reagents