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In vivo evolution of antibody CR3022 expands cross-neutralization of SARS-CoV-2 variants and informs pan-sarbecovirus immunity

Authors: Yanbin Fu, Ziqi Feng, Steven A Erickson, Peter J Halfmann, Lei Li, Jordan C Chervin, Chloe A Troxell, Jiayi Sun, Atsuhiro Yasuhara, Siriruk Changrob, Min Huang, Nai-Ying Zheng, Meng Yuan, Yoshihiro Kawaoka, Ian A Wilson, Patrick C Wilson

Journal: Cell Reports

PubMed ID: 41865371

Doi: 10.1016/j.celrep.2026.117137

Products & Services: Protein and Antibody Isolation

Chemoenzymatic synthesis of K29/K48-branched ubiquitin chains using LbPro* andOaAEP1 enzymes

Authors: Hongyi Cai, Xiangwei Wu, Shidian Wu, Lei Liu, Man Pan

Journal: CCS Chemistry

Doi: 10.31635/ccschem.026.202506451

Products & Services: Protein Electrophoresis and Western

Elucidating the Molecular Mechanism of 3D1 Antibody Binding to a Swine Enteric Coronavirus Antigen

Authors: Liangminghui Zhang, Ze Liang, Guang Yang, Lei Yan

Journal: Viruses

PubMed ID: 41754551

Doi: 10.3390/v18020208

Products & Services: Peptide Synthesis

ITGB1 Regulates Triple-Negative Breast Cancer Development by Modulating the Tumor Microenvironment

Authors: Nuozi Song, Siqi Chen, Lei Wang, Jessica Dang, Xu Cao, Stephanie Singh, Lu Yang, Jinhui Wang, Steven T Rosen, Yingyu Wang, Chun-Wei D Chen, Cheng Zhang, Mingye Feng

Journal: Advanced Science

PubMed ID: 41632816

Doi: 10.1002/advs.202513672

Triglycerides induce endoplasmic reticulum lipid bilayer stress to activate PERK and enhance antifungal immunity

Authors: Han Wu, Qing Shui, Xiaoxi Luan, Kexin Wang, Wei Zhao, Xiaopeng Qi, Bingyu Liu, Wanwei Sun, Chengjiang Gao

Journal: Molecular Therapy

PubMed ID: 41678331

Doi: 10.1016/j.celrep.2026.116976

Products & Services: Recombinant Proteins

An orthogonal CRISPR/Cpf1 platform for precise spatiotemporal gene regulation and osteoporotic fracture repair

Authors: Jie Zhao, Zengliang Wang, Lina Lu, Guoyun Bu, Zukang Miao, Yang Zhang, Yue Guo, Zhao Yang, Jianxiong Ma, Jun Jiao, Xinlong Ma

Journal: Molecular Therapy

PubMed ID: 41679307

Doi: 10.1016/j.crmeth.2025.101299

Phloretin targeting the 3CLpro Cys144 exhibits broad-spectrum antiviral activity against swine enteric coronavirus

Authors: Jiawei Xiao, Donghua Guo, Xiaoxu Xing, Limin Jiang, Shanshan Qi, Jun Wang, Wenfei Bai, Shiping Yu, Fanbo Shen, Xingyang Guo, Xinglin Wang, Wei Zhou, Hansong Li, Feiyu Zhao, Li Feng, Jialin Zhang, Yaru Xu, Dan Yang, Haixin Liu, Dongbo Sun

Journal: Molecular Therapy

PubMed ID: 41720346

Doi: 10.1016/j.virs.2026.02.011

Products & Services: Peptide Synthesis

Taming immune responses to AAV gene therapy by programmed in vivo Treg expansion

Authors: Lavesh Gwalani, Mincheol Park, Alexandra B Ysasi, Mona Motwani, Robert Jackson, Jie Bu, Zhengyu Luo, John Bladon, Edith L Pfister, Christian Mueller, Sourav R Choudhury

Journal: Molecular Therapy

PubMed ID: 41691369

Doi: 10.1016/j.ymthe.2026.02.019

Products & Services: Peptide Library Services

Personalized structural biology reveals the molecular mechanisms underlying heterogeneous epileptic phenotypes caused by de novo KCNC2 variants

Authors: Souhrid Mukherjee; Thomas A. Cassini; Ningning Hu; Tao Yang; Bian Li; Wangzhen Shen; Christopher W. Moth; David C. Rinker; Jonathan H. Sheehan; Joy D. Cogan; John H. Newman; Rizwan Hamid; Robert L. Macdonald; Dan M. Roden; Jens Meiler; Georg Kuenze; John A. Phillips; John A. Capra

Journal: Human Genetics and Genomics Advances

PubMed ID: 36035247

Doi: 10.1016/j.xhgg.2022.100131

Products & Services: Custom Vector Construction

In-silico and in-vitro study of novel antimicrobial peptide AM1 from Aegle marmelos against drug-resistant Staphylococcus aureus

Authors: Rudra Awdhesh Kumar Mishra; Gothandam Kodiveri Muthukaliannan

Journal: Scientific REPORTS

PubMed ID: 39468175

Doi: 10.1038/s41598-024-76553-0

Products & Services: Peptide Synthesis