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Tumor nutrient stress gives rise to a drug tolerant cell state in pancreatic cancer

Authors: Colin Sheehan; Lyndon Hu; Guillaume Cognet; Grace Croley; Thao Trang Nguyen; Anika Thomas-Toth; Darby Agovino; Patrick B. Jonker; Mumina Sadullozoda; Leah M. Ziolkowski; James K. Martin; Alica K. Beutel; Ranya Dano; Mohammed A. Khan; Christopher J. Halbrook; Kay F. Macleod; Christopher R. Weber; James L. LaBelle; Alexander Muir

Journal: biorxiv

PubMed ID: 40964288

Doi: 10.1101/2025.09.04.673818

Products & Services: Peptide Synthesis

hypocretin-1/hypocretin receptor 1 regulates neuroplasticity and cognitive function through hippocampal lactate homeostasis in depressed model

Authors: Bing Chen , Kangyu Jin , Jingyi Dong , Shangping Cheng , Lingzhuo Kong , Shaohua Hu , Zuobing Chen, Jing Lu

Journal: Advanced Science

PubMed ID: 39119889

Doi: 10.1002/advs.202405354

Products & Services: Protein Electrophoresis and Western Protein Electrophoresis and Western

Rupatadine-inhibited OTUD3 promotes DLBCL progression and immune evasion through deubiquitinating MYL12A and PD-L1

Authors: Ying Sui , Ziyang Shen, Xiaoyou Li 1, Ya Lu , SiTong Feng , Rong Ma, Jianzhong Wu , Changwen Jing, Zhuo Wang, Jifeng Feng , Haixia Cao

Journal: Cell death & disease

PubMed ID: 39097608

Doi: 10.038/s41419-024-06941-x

Products & Services: Protein and Antibody Isolation

Spatiotemporal coordination of antigen presentation and co-stimulatory signal for enhanced anti-tumor vaccination

Authors: Sha Peng , Yumeng Yan , Kenji Ogino , Guanghui Ma , Yufei Xia

Journal: Journal of controlled release

PubMed ID: 39153722

Doi: 10.1016/j.jconrel.2024.08.025.

Products & Services: Peptide Synthesis

A low-molecular-weight α-glucan from edible fungus Agaricus blazei Murrill activates macrophage TFEB-mediated antibacterial defense to combat implant-associated infection

Authors: Qishan Wang , Yuehong Wang , Yihao Liu , Kai Yuan , Yixuan Lin , Xian Qian , Hongyan Pei , Liangliang Weng , Kaijian Fan , Yihe Hu , Yiqi Yang

Journal: Carbohydrate Polymers

Doi: 10.1016/j.carbpol.2024.122659

Products & Services: Protein Electrophoresis and Western

siRNA nanoparticle targeting Usp20 lowers lipid levels and ameliorates metabolic syndrome in mice

Authors: Yi Ding 1, Qiu-Bing Chen , Hui Xu , Dilare Adi , Yi-Wen Ding , Wen-Jun Luo , Wen-Zhuo Zhu , Jia-Chen Xu , Xiaolu Zhao , Xiong-Jie Shi , Jie Luo , Hao Yin , Xiao-Yi Lu

Journal: Journal of lipid research

PubMed ID: 39173829

Doi: 10.1016/j.jlr.2024.100626

Products & Services: Custom RNAi Services

Channelrhodopsins with distinct chromophores and binding patterns

Authors: Yuanyue Shan , Liping Zhao , Meiyu Chen , Xiao Li , Mingfeng Zhang , Duanqing Pei

Journal: Nature Communications

PubMed ID: 39181878

Doi: 10.1038/s41467-024-51811-x

Products & Services: Protein and Antibody Isolation

Anattachment glycoprotein nanoparticle elicits broadly neutralizing antibodies and protects against lethal Nipah virus infection

Authors: Dan Zhou , Rao Cheng , Yanfeng Yao , Gan Zhang , Xin Li , Bingjie Wang , Yong Wang , Feiyang Yu , Shangyu Yang , Hang Liu , Ge Gao , Yun Peng , Miaoyu Chen , Zengqin Deng , Haiyan Zhao

Journal: npj Vaccines

PubMed ID: 39217188

Doi: 10.1038/s41541-024-00954-5

Products & Services: Protein and Antibody Isolation

Human mitochondrial carriers of the SLC25 family function as monomers exchanging substrates with a ping-pong kinetic mechanism

Authors: Camila Cimadamore-Werthein , Martin S King , Denis Lacabanne , Eva Pyrihová , Stephany Jaiquel Baron , Edmund Rs Kunji

Journal: EMBO J

PubMed ID: 38937634

Doi: 10.1038/s44318-024-00150-0.

Products & Services: Gene Synthesis

Cellular N-Myristoyl Transferases Are Required for Mammarenavirus Multiplication

Authors: Haydar Witwit , Carlos Alberto Betancourt , Beatrice Cubitt , Roaa Khafaji , Heinrich Kowalski , Nathaniel Jackson , Chengjin Ye , Luis Martinez-Sobrido , Juan C de la Torre

Journal: Viruses

PubMed ID: 39339839

Doi: 10.3390/v16091362

Products & Services: Catalog Antibodies