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Allosteric Covalent Inhibitors of the STAT3 Transcription Factor from Virtual Screening

Authors: Tibor Viktor Szalai; Vincenzo di Lorenzo; Nikolett P czka; Levente M. Mihalovits; L szl Petri; Qirat F. Ashraf; Elvin D. de Araujo; Viktor Honti; D vid Bajusz; Gy rgy M. Keser

Journal: ACS medicinal chemistry letters

PubMed ID: 40529081

Doi: 10.1021/acsmedchemlett.4c00622

Products & Services: Peptide Synthesis

Lysophospholipid signaling coordinates outer membrane homeostasis in Escherichia coli

Authors: Gerald R. Enverso; M. Stephen Trent

Journal: MBio

PubMed ID: 41979331

Doi: 10.1128/mbio.00567-26

Products & Services: Gene Synthesis

Design of a Fluorescence Polarization Probe for Enterovirus 2C Proteins

Authors: Kan Li; Hiwot A Demssie; Jun Wang

Journal: Journal of Medicinal Chemistry

PubMed ID: 40542722

Doi: 10.1021/acs.jmedchem.5c01219

Novel peptide inhibitor for the Chikungunya virus nsP2 protease: Identification and characterization

Authors: Mohammadamin Mastalipour; Ian Gering; M nika Aparecida Coronado; Jorge Enrique Hern ndez Gonz lez; Dieter Willbold; Raphael Josef Eberle

Journal: Current Research in Microbial Sciences

PubMed ID: 40165933

Doi: 10.1016/j.crmicr.2025.100376

Products & Services: Peptide Synthesis

A maternal brain hormone that builds bone

Authors: Muriel E Babey, William C Krause, Kun Chen, Candice B Herber, Zsofia Torok, Joni Nikkanen, Ruben Rodriguez, Xiao Zhang, Fernanda Castro-Navarro, Yuting Wang, Erika E Wheeler, Saul Villeda, J Kent Leach, Nancy E Lane, Erica L Scheller, Charles K F Chan, Thomas H Ambrosi, Holly A Ingraham

Journal: Nature

PubMed ID: 38987585

Products & Services: Peptide Synthesis

Preparation of polyclonal antibody against thrombospondin 2 recombinant protein and its functional verification in pulmonary hypertension syndrome in broilers

Authors: Wen Peng, Chenxi Jiang, Gaofeng Cai, Liling Liu, Xiaoquan Guo, Xiaona Gao, Guyue Li, Zhanhong Zheng, Pei Liu, Ping Liu

Journal: International Journal of Biological Macromolecules

PubMed ID: 38906344

Doi: doi.org/10.1016/j.ijbiomac.2024.133284

Products & Services: Protein and Antibody Isolation

A two-pronged nanostrategy of iron metabolism disruption to synergize tumor therapy by triggering the paraptosis-apoptosis hybrid pathway

Authors: Huali Lei , Guanghui Hou , Lin Liu , Zifan Pei , Youdong Chen , Yujie Lu , Nalin Yang , Shumin Sun , Liang Cheng

Journal: ACS Nano

PubMed ID: 39121010

Doi: 10.1021/acsnano.4c06199

Products & Services: Peptide Synthesis

25-Hydroxycholesterol inhibits Hantavirus infection by reprogramming cholesterol metabolism

Authors: Yamei Dang , Yuan Wang , Jing Wei , Hui Zhang , Qiqi Yang , Bin Wang , Jia Li , Chuantao Ye , Yang Chen , Peijun Han , Xiaolei Jin , Jia Wang , Xiaohui Bao , He Liu , Hongwei Ma , Liang Zhang , Linfeng Cheng , Yangchao Dong , Yinlan Bai , Yinghui Li , Yingfeng Lei , Zhikai Xu , Fanglin Zhang , Wei Ye

Journal: FREE RADICAL BIOLOGY AND MEDICINE

PubMed ID: 39209137

Doi: 10.1016/j.freeradbiomed.2024.08.029

Products & Services: Codon Optimization

Activation of ATF3 via the integrated stress response pathway regulates innate immune response to restrict Zika virus

Authors: Pheonah Badu , Gabriele Baniulyte , Morgan A Sammons , Cara T Pager

Journal: Virology Journal

PubMed ID: 39212382

Doi: 10.1128/jvi.01055-24

Products & Services: CRISPR RNAs/Cas9 Proteins(INACTIVE)

Reduced Cross-Protective Potential of Omicron Compared to Ancestral SARS-CoV-2 Spike Vaccines Against Potentially Zoonotic Coronaviruses

Authors: Tyler RennerMatthew StuibleBrian CassSylvie PerretJulie GuimondSimon Lord-DufourMichael J. McCluskieYves DurocherBassel Akache