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4-aminopyridine attenuates inflammation and apoptosis and increases angiogenesis to promote skin regeneration following a burn injury in mice

Authors: Rahul V G , Govindaraj Ellur , Amir A Gaber , Prem Kumar Govindappa , John C Elfar

Journal: Cell Death Discov

PubMed ID: 39366954

Doi: 10.1038/s41420-024-02199-6

Products & Services: Protein and Antibody Isolation

Vaccination generates functional progenitor tumor-specific CD8 T cells and long-term tumor control

Authors: Carlos R Detrés Román, Megan M Erwin, Michael W Rudloff, Frank Revetta, Kristen A Murray, Natalie R Favret, Jessica J Roetman, Joseph T Roland, Mary K Washington, Mary Philip

Journal: J Immunother Cancer

PubMed ID: 39362791

Doi: 10.1136/jitc-2024-009129

Products & Services: Peptide Synthesis

Broad cross neutralizing antibodies against sarbecoviruses generated by SARS-CoV-2 infection and vaccination in humans

Authors: Yabin Hu, Qian Wu, Fangfang Chang, Jing Yang, Xiaoyue Zhang, Qijie Wang, Jun Chen, Shishan Teng, Yongchen Liu, Xingyu Zheng, You Wang, Rui Lu, Dong Pan, Zhanpeng Liu, Fen Liu, Tianyi Xie, Chanfeng Wu, Yinggen Tang, Fei Tang, Jun Qian, Hongying Chen, Wenpei Liu, Yi-Ping Li, Xiaowang Qu

Journal: npj Vaccines

PubMed ID: 39438493

Doi: 10.1038/s41541-024-00997-8

Products & Services: Gene Synthesis

Gegen Qinlian Decoction reverses oxaliplatin resistance in colorectal cancer by inhibiting YTHDF1-regulated m6A modification of GLS1

Authors: Xiang Lin , Li Xu , Meng Gu , Huan Shao , Li Yao , Xuan Huang

Journal: Phytomedicine

PubMed ID: 39089089

Doi: 10.1016/j.phymed.2024.155906

Products & Services: Protein Electrophoresis and Western

Structure of Plasmodium vivax N -myristoyltransferase with inhibitor IMP-1088: exploring an NMT inhibitor for antimalarial therapy

Authors: Alex Mendez; Cydni Bolling; Shane Taylor; Stanley Makumire; Bart Staker; Alexandra Reers; Brad Hammerson; Stephen J. Mayclin; Jan Abendroth; Donald D. Lorimer; Thomas E. Edwards; Edward W. Tate; Sandhya Subramanian; Andrew S. Bell; Peter J. Myler; Oluwatoyin A. Asojo; Graham Chakafana

Journal: Acta Crystallographica Section F: Structural Biology Communications

PubMed ID: 39655507

Doi: 10.1107/S2053230X24011348

Efficient Design of Affilin Protein Binders for HER3

Authors: Anna M. Diaz-Rovira; Jonathan Lotze; Gregor Hoffmann; Chiara Pallara; Alexis Molina; Ina Coburger; Manja Gloser-Br unig; Maren Meysing; Madlen Zwarg; Luc a D az; Victor Guallar; Eva Bosse-Doenecke; Sergi Roda

Journal: International Journal of Molecular Sciences

PubMed ID: 40429825

Doi: 10.3390/ijms26104683

Products & Services: Catalog Antibodies

Far-red light photoacclimation in a desert Chroococcidiopsis strain with a reduced FaRLiP gene cluster and expression of its chlorophyll f synthase in space-resistant isolates

Authors: Giorgia di Stefano, Mariano Battistuzzi, Nicoletta La Rocca, Vera M Selinger, Dennis J Nürnberg, Daniela Billi

Journal: Frontiers in Microbiology

PubMed ID: 39328908

Doi: 10.3389/fmicb.2024.1450575

Products & Services: Gene Synthesis

Targeting Ras-, Rho-, and Rab-family GTPases via a conserved cryptic pocket

Authors: Johannes Morstein , Victoria Bowcut , Micah Fernando , Yue Yang , Lawrence Zhu , Meredith L Jenkins , John T Evans , Keelan Z Guiley , D Matthew Peacock , Sophie Krahnke , Zhi Lin , Katrine A Taran , Benjamin J Huang , Andrew G Stephen , John E Burke , Felice C Lightstone , Kevan M Shokat

Journal: Cell

PubMed ID: 39255801

Doi: 10.1016/j.cell.2024.08.017

Products & Services: DNA Sequencing

Accelerated discovery and miniaturization of novel single-stranded cytidine deaminases

Authors: Jiacheng Deng,† , Xueyuan Li,† , Hao Yu,† , Lin Yang1, Ziru Wang1, Wenfeng Yi, Ying Liu, Wenyu Xiao, Hongyong Xiang, Zicong Xie, Dongmei Lv, Hongsheng Ouyang, Daxin Pang, * and Hongming Yuan

Journal: Nucleic Acids Research

PubMed ID: 39271120

Doi: doi.org/10.1093/nar/gkae800

Products & Services: Gene Synthesis

Rational design of a DNA-launched live attenuated vaccine against human enterovirus 71

Authors: Rong-Rong Zhang 1, Meng-Jiao He 1, Chao Zhou 1, Yan-Peng Xu 1, Wei Tang 1, Tian-Shu Cao 1, Zheng-Jian Wang , Mei Wu , Tao Ming , Yi-Jiao Huang , Meng-Xu Sun , Hui Zhao , Yong-Qiang Deng , Xiao-Feng Li , Bin Wang , Qing Ye , Cheng-Feng Qin

Journal: VIROLOGICA SINICA

PubMed ID: 39306193

Doi: 10.1016/j.virs.2024.09.008

Products & Services: Peptide Tools