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Deep mutational scanning and machine learning for the analysis of antimicrobial-peptide features driving membrane selectivity

Authors: Justin R. Randall; Luiz C. Vieira; Claus O. Wilke; Bryan W. Davies

Journal: Nature biomedical engineering

PubMed ID: 39085646

Doi: 10.1038/s41551-024-01243-1

Products & Services: Peptide Synthesis

Dictating the spatial-temporal delivery of molecular adjuvant and antigen for the enhanced vaccination

Authors: Yumeng Yan , Xiaonan Huang , Lili Yuan , To Ngai , Guanghui Ma , Yufei Xia

Journal: Biomaterials

PubMed ID: 38968687

Doi: 10.1016/j.biomaterials.2024.122697

Products & Services: Peptide Synthesis

Engineered Magneto-Piezoelectric Nanoparticles-Enhanced Scaffolds Disrupt Biofilms and Activate Oxidative Phosphorylation in Icam1+ Macrophages for Infectious Bone Defect Regeneration

Authors: Hao Wu , Changcheng Chen , Jiangfeng Li , Dongmei Yu , Xun Wu , Hai Huang , Zhen Tang , Qi Wu , Shichao Yan , Ning Wang , Mo Wang , Feilong Wei , Yunlong Yu , Duan Wang , Mengting Shi , Xusong Yue , Pengfei Cao , Zenghui Zheng , Xiaokang Li , Baolin Guo , Lei Shi , Zheng Guo

Journal: ACS Nano

PubMed ID: 39690461

Doi: 10.1021/acsnano.4c13562

Products & Services: Protein Electrophoresis and Western

Beyond the MEP Pathway: A novel kinase required for prenol utilization by malaria parasites

Authors: Marcell Crispim; Ignasi Bofill Verdaguer; Agust n Hern ndez; Thales Kronenberger; ngel Fenollar; Lydia Fumiko Yamaguchi; Mar a P a Alberione; Miriam Ramirez; Sandra Souza de Oliveira; Alejandro Miguel Katzin; Luis Izquierdo; Kirk W. Deitsch; James J Collins III; Kirk W. Deitsch; James J Collins III; Kirk W. Deitsch; James J Collins III; Kirk W. Deitsch; James J Collins III

Journal: PLOS Pathogens

PubMed ID: 38277417

Doi: 10.1371/journal.ppat.1011557

Products & Services: PCR Cloning and Subcloning

Beyond the MEP Pathway: A novel kinase required for prenol utilization by malaria parasites

Journal: PLOS Pathogens

PubMed ID: 38277417

Doi: 10.1371/journal.ppat.1011557

Products & Services: PCR Cloning and Subcloning

Beyond the MEP Pathway: A novel kinase required for prenol utilization by malaria parasites

Journal: PLOS Pathogens

PubMed ID: 38277417

Doi: 10.1371/journal.ppat.1011557

Products & Services: PCR Cloning and Subcloning

Remotely Sequential Activation of Biofunctional MXenes for Spatiotemporally Controlled Photothermal Cancer Therapy Integrated with Multimodal Imaging

Authors: Jing Jia , Xiaobo Zhang , Yiran Li , Tian Wang , Ying An , Xinrong Yan , Bin Liu , Chaoyi Yang , Huangxian Ju

Journal: Small

PubMed ID: 39665387

Doi: 10.1002/smll.202410535

Products & Services: Synthetic Guide RNA

High-Speed Sequential DNA Computing Using a Solid-State DNA Origami Register

Authors: Qian Zhang, Mingqiang Li, Yuqing Tang, Jinyan Zhang, Chenyun Sun, Yaya Hao, Jianing Cheng, Xiaodong Xie, Sisi Jia, Hui Lv, Fei Wang, and Chunhai Fan

Journal: ACS central science

Doi: doi.org/10.1021/acscentsci.4c01557

Products & Services: CRISPR KI Templates

Lithocholic acid binds TULP3 to activate sirtuins and AMPK to slow down ageing

Authors: Qi Qu, Yan Chen, Yu Wang, Weiche Wang, Shating Long, Heng-Ye Yang, Jianfeng Wu, Mengqi Li, Xiao Tian, Xiaoyan Wei, Yan-Hui Liu, Shengrong Xu, Jinye Xiong, Chunyan Yang, Zhenhua Wu, Xi Huang, Changchuan Xie, Yaying Wu, Zheni Xu, Cixiong Zhang, Baoding Zhang, Jin-Wei Feng, Junjie Chen, Yuanji Feng, Huapan Fang, Liyun Lin, Z K Xie, Beibei Sun, Huayu Tian, Yong Yu, Hai-Long Piao, Xiao-Song Xie, Xianming Deng, Chen-Song Zhang, Sheng-Cai Lin

Journal: Nature

PubMed ID: 39695235

Doi: 10.1038/s41586-024-08348-2

Products & Services: Synthetic Guide RNA

Structural Insights into the High Basal Activity and Inverse Agonism of the Orphan GPR6 Receptor Implicated in Parkinson s Disease

Authors: Mahta Barekatain; Linda C. Johansson; Jordy H. Lam; Hao Chang; Anastasiia V. Sadybekov; Gye Won Han; Joseph Russo; Joshua Bliesath; Nicola Brice; Mark B. L. Carlton; Kumar S. Saikatendu; Hukai Sun; Sean T. Murphy; Holger Monenschein; Hans H. Schiffer; Petr Popov; Corinne A. Lutomski; Carol V. Robinson; Zhi-Jie Liu; Tian Hua; Vsevolod Katritch; Vadim Cherezov

Journal: Science Signaling

PubMed ID: 39626010

Doi: 10.1126/scisignal.ado8741