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Intestine-Decipher Engineered Capsules Protect Against Sepsis-induced Intestinal Injury via Broad-spectrum Anti-inflammation and Parthanatos Inhibition

Authors: Yan Yan, Bin Li, Qiuxia Gao, Miao Wu, Hua Ma, Jiawei Bai, Chengtai Ma, Xinyu Xie, Yuan Gong, Lingqi Xu, Xiaoxue Li, Wei Wang, Yanqiu Wu, Jiamei Wang, Huanhuan Wang, Yi Feng, Yunlong Zhang, Peiran Li, Huimin Shi, Fei Ma, Yue Jia, Han Duan, Xinting Fu, Wenying Wang, Liying Zhan, Xianjin Du, Huiting Zhou, Yuhui Liao

Journal: Advanced Science

PubMed ID: 39836501

Doi: 10.1002/advs.202412799

Products & Services: Protein Electrophoresis and Western

Microenvironment actuated CAR T cells improve solid tumor efficacy without toxicity

Authors: Kristen C Vogt , Pedro C Silberman , Qianqian Lin , James E Han , Amy Laflin , Hendryck A Gellineau , Daniel A Heller , David A Scheinberg

Journal: SCIENCE ADVANCES

PubMed ID: 39841845

Doi: 10.1126/sciadv.ads3403

Products & Services: Gene Synthesis

Construction and iterative redesign of synXVI a 903 kb synthetic Saccharomyces cerevisiae chromosome

Authors: Hugh D. Goold, Heinrich Kroukamp, Paige E. Erpf, Yu Zhao, Philip Kelso, Julie Calame, John J. B. Timmins, Elizabeth L. I. Wightman, Kai Peng, Alexander C. Carpenter, Briardo Llorente, Carmen Hawthorne, Samuel Clay, Niël van Wyk, Elizabeth L. Daniel, Fergus Harrison, Felix Meier, Robert D. Willows, Yizhi Cai, Roy S. K. Walker, Xin Xu, Monica I. Espinosa, Giovanni Stracquadanio, Joel S. Bader, …Isak S. Pretorius

Journal: Nature Communications

PubMed ID: 39833175

Doi: 10.1038/s41467-024-55318-3

Products & Services: Gene Synthesis

Chemical tools to define and manipulate interferon-inducible Ubl protease USP18

Authors: Griffin J. Davis, Anthony O. Omole, Yejin Jung, Wioletta Rut, Ronald Holewinski, Kiall F. Suazo, Hong-Rae Kim, Mo Yang, Thorkell Andresson, Marcin Drag & Euna Yoo

Journal: Nature Communications

PubMed ID: 39843430

Doi: 10.1038/s41467-025-56336-5

Products & Services: Plasmid DNA Preparation

Nuclear Condensates of WW Domain-Containing Adaptor With Coiled-Coil Regulate Mitophagy via Alternative Splicing

Authors: Jiahe Wang, Yi Fan, Guowen Luo, Liang Xiong, Lijie Wang, Zhuoxuan Wu, Jiayi Wang, Zhengying Peng, Clifford J Rosen, Kefeng Lu, Junjun Jing, Quan Yuan, Zhenwei Zhang, Chenchen Zhou

Journal: Advanced Science

PubMed ID: 39840526

Doi: 10.1002/advs.202406759

Products & Services: Protein and Antibody Isolation

Evolving antibody response to SARS-CoV-2 antigenic shift from XBB to JN.1

Authors: Fanchong Jian, Jing Wang, Ayijiang Yisimayi, Weiliang Song, Yanli Xu, Xiaosu Chen, Xiao Niu, Sijie Yang, Yuanling Yu, Peng Wang, Haiyan Sun, Lingling Yu, Jing Wang, Yao Wang, Ran An, Wenjing Wang, Miaomiao Ma, Tianhe Xiao, Qingqing Gu, Fei Shao, Youchun Wang, Zhongyang Shen, Ronghua Jin, Yunlong Cao

Journal: Nature

PubMed ID: 39510125

Doi: 10.1038/s41586-024-08315-x

Products & Services: Gene Synthesis Codon Optimization

Spontaneous base flipping helps drive Nsp15’s preferences in double stranded RNA substrates

Authors: Zoe M. Wright, Kevin John Butay, Juno M. Krahn, Isha M. Wilson, Scott A. Gabel, Eugene F. DeRose, Israa S. Hissein, Jason G. Williams, Mario J. Borgnia, Meredith N. Frazier, Geoffrey A. Mueller & Robin E. Stanley

Journal: Nature Communications

PubMed ID: 39755678

Doi: 10.1038/s41467-024-55682-0

Divergent evolution of opposite base specificity and single-stranded DNA activity in animal and plant AP endonucleases

Authors: Marina Jordano-Raya, Carol E Schrader, Rafael R Ariza, Teresa Roldán-Arjona, Dolores Córdoba-Cañero

Journal: Nucleic Acids Research

PubMed ID: 39778867

Doi: 10.1093/nar/gkae1297

Products & Services: Codon Optimization

A high-fidelity CRISPR-Cas13 system improves abnormalities associated with C9ORF72-linked ALS/FTD

Authors: Tristan X. McCallister, Colin K. W. Lim, Mayuri Singh, Sijia Zhang, Najah S. Ahsan, William M. Terpstra, Alisha Y. Xiong, M. Alejandra Zeballos C, Jackson E. Powell, Jenny Drnevich, Yifei Kang & Thomas Gaj

Journal: Nature Communications

PubMed ID: 39779681

Doi: 10.1038/s41467-024-55548-5

Products & Services: Custom Vector Construction

Evolution of Omicron lineage towards increased fitness in the upper respiratory tract in the absence of severe lung pathology

Authors: Arthur Wickenhagen, Meaghan Flagg, Julia R. Port, Claude Kwe Yinda, Kerry Goldin, Shane Gallogly, Jonathan E. Schulz, Tessa Lutterman, Brandi N. Williamson, Franziska Kaiser, Reshma K. Mukesh, Sarah van Tol, Brian Smith, Neeltje van Doremalen, Colin A. Russell, Emmie de Wit & Vincent J. Munster

Journal: Nature Communications

PubMed ID: 39799119

Doi: 10.1038/s41467-025-55938-3

Products & Services: Gene Synthesis