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CAR affinity modulates the sensitivity of CAR-T cells to PD-1/PD-L1-mediated inhibition
Authors: Irene Andreu-Saumell, Alba Rodriguez-Garcia, Vanessa Mühlgrabner, Marta Gimenez-Alejandre, Berta Marzal, Joan Castellsagué, Fara Brasó-Maristany, Hugo Calderon, Laura Angelats, Salut Colell, Mara Nuding, Marta Soria-Castellano, Paula Barbao, Aleix Prat, Alvaro Urbano-Ispizua, Johannes B Huppa, Sonia Guedan
Journal: Nat Commun
PubMed ID: 38670972
Doi: 10.1038/s41467-024-47799-z
Products & Services: Catalog Peptides   
An ultraviolet-driven rescue pathway for oxidative stress to eye lens protein human gamma-D crystallin
Authors: Jake A Hill, Yvonne Nyathi, Sam Horrell, David von Stetten, Danny Axford, Robin L Owen, Godfrey S Beddard, Arwen R Pearson, Helen M Ginn, Briony A Yorke
Journal: Commun Chem
PubMed ID: 38600176
Doi: 10.1038/s42004-024-01163-w
Products & Services: Mutant Libraries   
Online monitoring of protein refolding in inclusion body processing using intrinsic fluorescence
Authors: Chika Linda Igwe, Don Fabian Müller, Florian Gisperg, Jan Niklas Pauk, Matthias Kierein, Mohamed Elshazly, Robert Klausser, Julian Kopp, Oliver Spadiut, Eva Přáda Brichtová
Journal: Anal Bioanal Chem
PubMed ID: 38573344
Doi: 10.1007/s00216-024-05249-1
Products & Services: Codon Optimization   
Immunometric and functional measurement of endogenous vasoinhibin in human sera
Authors: Magdalena Zamora, David Harris, Nils Davies, Johannes Ebnet, Peter Radermacher, Cosima Brucker, Christiane Waller, Juan Pablo Robles, Thomas Bertsch, Carmen Clapp, Jakob Triebel
Journal: Front Endocrinol (Lausanne)
PubMed ID: 38742198
Doi: 10.3389/fendo.2024.1345996
Products & Services: Recombinant Proteins   
The Female-Biased General Odorant Binding Protein 2 of Displays Binding Affinity for Biologically Active Host Plant Volatiles
Authors: Jingjing Tu, Zehua Wang, Fan Yang, Han Liu, Guanghang Qiao, Aihuan Zhang, Shanning Wang
Journal: Biology (Basel)
PubMed ID: 38666886
Doi: 10.3390/biology13040274
Products & Services: Gene Synthesis   
Streptococcus pneumoniae endopeptidase O induces trained immunity and confers protection against various pathogenic infections
Authors: Wenlong Xu, Yuan Yuan, Zhaoche Shu, Ting Guo, Bichen Liu, Jiangming Xiao, Lian Li, Yibin Yin, Xuemei Zhang
Journal: Clin Immunol
PubMed ID: 38663493
Doi: 10.1016/j.clim.2024.110226
Products & Services: Molecular Biology Reagents   
P66 is a bacterial mimic of CD47 that binds the anti-phagocytic receptor SIRPα and facilitates macrophage evasion by
Authors: Michal Caspi Tal, Paige S Hansen, Haley A Ogasawara, Qingying Feng, Regan F Volk, Brandon Lee, Sara E Casebeer, Grace S Blacker, Maia Shoham, Sarah D Galloway, Anne L Sapiro, Beth Hayes, Laughing Bear Torrez Dulgeroff, Tal Raveh, Venkata Raveendra Pothineni, Hari-Hara Sk Potula, Jayakumar Rajadas, Effie E Bastounis, Seemay Chou, William H Robinson, Jenifer Coburn, Irving L Weissman, Balyn W Zaro
Journal: biorxiv
PubMed ID: 38746193
Doi: 10.1101/2024.04.29.591704
Products & Services: Proteins, Expression, Isolation and Analysis   
Auto-inhibition and activation of a short Argonaute-associated TIR-APAZ defense system
Authors: Lijie Guo, Pingping Huang, Zhaoxing Li, Young-Cheul Shin, Purui Yan, Meiling Lu, Meirong Chen, Yibei Xiao
Journal: Nat Chem Biol
PubMed ID: 37932527
Doi: 10.1038/s41589-023-01478-0
Products & Services: Molecular Biology Reagents   Gene Synthesis   
Mechanosensitive channel MscL gating transitions coupling with constriction point shift
Authors: Mingfeng Zhang, Siyang Tang, Xiaomin Wang, Sanhua Fang, Yuezhou Li
Journal: Protein Sci
PubMed ID: 38501596
Doi: 10.1002/pro.4965
Products & Services: Proteins, Expression, Isolation and Analysis   
An Omicron-specific, self-amplifying mRNA booster vaccine for COVID-19: a phase 2/3 randomized trial
Authors: Amit Saraf, Rohan Gurjar, Swarnendu Kaviraj, Aishwarya Kulkarni, Durgesh Kumar, Ruta Kulkarni, Rashmi Virkar, Jayashri Krishnan, Anjali Yadav, Ekta Baranwal, Ajay Singh, Arjun Raghuwanshi, Praveen Agarwal, Laxman Savergave, Sanjay Singh; GEMCOVAC-OM Study Investigators
Journal: nature medicine
PubMed ID: 38637636
Doi: 10.1038/s41591-024-02955-2
Products & Services: Serology SARS-Cov-2 detection kits   

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