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页码: 262/5140 每页显示数量

Rapamycin nanoparticles increase the therapeutic window of engineered interleukin-2 and drive expansion of antigen-specific regulatory T cells for protection against autoimmune disease

Authors: Takashi Kei Kishimoto, Max Fournier, Alicia Michaud, Gina Rizzo, Christopher Roy, Teresa Capela, Natasha Nukolova, Ning Li, Liam Doyle, Fen-Ni Fu, Derek VanDyke, Peter G Traber, Jamie B Spangler, Sheldon S Leung, Petr O Ilyinskii

Journal: J Autoimmun

PubMed ID: 37844543

Doi: 10.1016/j.jaut.2023.103125

Products & Services: Proteins, Expression, Isolation and Analysis

Nucleic acid-triggered NADase activation of a short prokaryotic Argonaute

Authors: Xiaopan Gao , Kun Shang , Kaixiang Zhu , Linyue Wang , Zhixia Mu , Xingke Fu , Xia Yu , Bo Qin , Hongtao Zhu , Wei Ding , Sheng Cui

Journal: Nature .

PubMed ID: 37783228

Doi: 10.1038/s41586-023-06665-6

Products & Services: DNA Sequencing

Plant-Based Meat Analogues Weaken Gastrointestinal Digestive Function and Show Less Digestibility Than Real Meat in Mice

Authors: Yunting Xie , Linlin Cai , Zhiji Huang , Kai Shan , Xinglian Xu , Guanghong Zhou , Chunbao Li

Journal: J Agric Food Chem .

PubMed ID: 36070521

Doi: 10.1021/acs.jafc.2c04246

Products & Services: Gene Synthesis

Single Amino Acid Mutation Decouples Photochemistry of the BLUF Domain from the Enzymatic Function of OaPAC and Drives the Enzyme to a Switched-on State

Authors: Jinnette Tolentino Collado, Emoke Bodis, Jonatan Pasitka, Mihaly Szucs, Zsuzsanna Fekete, Nikolett Kis-Bicskei, Elek Telek, Kinga Pozsonyi, Sofia M Kapetanaki, Greg Greetham, Peter J Tonge, Stephen R Meech, Andras Lukacs

Journal: J Mol Biol

PubMed ID: 37827329

Doi: 10.1016/j.jmb.2023.168312

Products & Services: Proteins, Expression, Isolation and Analysis

Rational Design of Taxadiene Hydroxylase by Ancestral Enzyme Construction and the Elucidation of Key Amino Acids

Authors: Zihan Zhang, Longhao Huang, Zhi-Jun Zhang, Jian-He Xu, Hui-Lei Yu

Journal: Biochemistry

PubMed ID: 37902563

Doi: 10.1021/acs.biochem.3c00411

Products & Services: Proteins, Expression, Isolation and Analysis

FHL1 promotes chikungunya and o'nyong-nyong virus infection and pathogenesis with implications for alphavirus vaccine design

Authors: Wern Hann Ng, Xiang Liu, Zheng L Ling, Camilla N O Santos, Lucas S Magalhães, Andrew J Kueh, Marco J Herold, Adam Taylor, Joseph R Freitas, Sandra Koit, Sainan Wang, Andrew R Lloyd, Mauro M Teixeira, Andres Merits, Roque P Almeida, Nicholas J C King, Suresh Mahalingam

Journal: Nat Commun

PubMed ID: 37884534

Doi: 10.1038/s41467-023-42330-2

Products & Services: Proteins, Expression, Isolation and Analysis

Biochemical and biophysical properties of a rare TTRA81V mutation causing mild transthyretin amyloid cardiomyopathy

Authors: Qiuyan Sha, Yanli Zhang, Mengdie Wang, Jialu Sun, Yunlong Zhang, Xinxin Zhang, Ning Wang, Yu Liu, Ying Liu

Journal: ESC Heart Fail

PubMed ID: 37827496

Doi: 10.1002/ehf2.14543

Products & Services: Proteins, Expression, Isolation and Analysis

ATOR-1017 (evunzekibart), an Fc-gamma receptor conditional 4-1BB agonist designed for optimal safety and efficacy, activates exhausted T cells in combination with anti-PD-1

Authors: Karin Enell Smith, Sara Fritzell, Anneli Nilsson, Karin Barchan, Anna Rosén, Lena Schultz, Laura Varas, Anna Säll, Nadia Rose, Maria Håkansson, Laura von Schantz, Peter Ellmark

Journal: Cancer Immunol Immunother

PubMed ID: 37796298

Doi: 10.1007/s00262-023-03548-7

Products & Services: Gene Synthesis

Industry updates from the field of stem cell research and regenerative medicine in August 2023

Authors: Dusko Ilic, Mirjana Liovic

Journal: Regen Med

PubMed ID: 37786963

Doi: 10.2217/rme-2023-0181

Products & Services: Proteins, Expression, Isolation and Analysis

Author Correction: A ferritin-based COVID-19 nanoparticle vaccine that elicits robust, durable, broad-spectrum neutralizing antisera in non-human primates

Authors: Payton A-B Weidenbacher, Mrinmoy Sanyal, Natalia Friedland, Shaogeng Tang, Prabhu S Arunachalam, Mengyun Hu, Ozan S Kumru, Mary Kate Morris, Jane Fontenot, Lisa Shirreff, Jonathan Do, Ya-Chen Cheng, Gayathri Vasudevan, Mark B Feinberg, Francois J Villinger, Carl Hanson, Sangeeta B Joshi, David B Volkin, Bali Pulendran, Peter S Kim

Journal: Nat Commun

PubMed ID: 37798288

Doi: 10.1038/s41467-023-42061-4

Products & Services: Peptide Synthesis

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