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Mammalian PIWI–piRNA–target complexes reveal features for broad and efficient target silencing
Authors: Zhiqing Li, Zhenzhen Li, Yuqi Zhang, Lunni Zhou, Qikui Xu, Lili Li, Lin Zeng, Junchao Xue, Huilin Niu, Jing Zhong, Qilu Yu, Dengfeng Li, Miao Gui, Yongping Huang, Shikui Tu, Zhao Zhang, Chun-Qing Song, Jianping Wu，En-Zhi Shen
Journal: Nat Struct Mol Biol
PubMed ID: 38658622
Doi: 10.1038/s41594-024-01287-6.
Products & Services: Proteins, Expression, Isolation and Analysis   
Resistance mechanisms of SARS-CoV-2 3CLpro to the non-covalent inhibitor WU-04
Authors: Lijing Zhang, Xuping Xie, Hannan Luo, Runtong Qian, Yang Yang, Hongtao Yu, Jing Huang, Pei-Yong Shi, Qi Hu
Journal: Cell Discov
PubMed ID: 38594245
Doi: 10.1038/s41421-024-00673-0
Products & Services: Proteins, Expression, Isolation and Analysis   
A novel protein CYTB-187AA encoded by the mitochondrial gene CYTB modulates mammalian early development
Authors: Zhijuan Hu 1, Liang Yang 2, Maolei Zhang 2, Haite Tang 2, Yile Huang 3, Yujie Su 4, Yingzhe Ding 3, Chong Li 2, Mengfei Wang 4, Yunhao Zhou 4, Qing Zhang 5, Liman Guo 5, Yue Wu 5, Qianqian Wang 6, Ning Liu 6, Haoran Kang 2, Yi Wu 2, Deyang Yao 2, Yukun Li 4, Zifeng Ruan 4, Hao Wang 2, Feixiang Bao 2, Guopan Liu 3, Junwei Wang 2, Yaofeng Wang 3, Wuming Wang 7, Gang Lu 7, Dajiang Qin 8, Duanqing Pei 9, Wai-Yee Chan 7, Xingguo Liu
Journal: Cell Metab
PubMed ID: 38703762
Doi: 10.1016/j.cmet.2024.04.012
Products & Services: Monoclonal Antibody Services   
Protein language models-assisted optimization of a uracil-N-glycosylase variant enables programmable T-to-G and T-to-C base editing
Authors: Yan He, Xibin Zhou, Chong Chang, Ge Chen, Weikuan Liu, Geng Li, Xiaoqi Fan, Mingsun Sun, Chensi Miao, Qianyue Huang, Yunqing Ma, Fajie Yuan, Xing Chang
Journal: Mol Cell
PubMed ID: 38377993
Doi: 10.1016/j.molcel.2024.01.021
Products & Services: Synthetic sgRNA and crRNA Service   
Identification and characterization of emGalaseE, a β-1,4 galactosidase from Elizabethkingia meningoseptica, and its application on living cell surface
Authors: Yongliang Tong, Xinrong Lu, Danfeng Shen, Lin Rao, Lin Zou, Shaoxian Lyu, Linlin Hou, Guiqin Sun, Li Chen
Journal: Biological Macromolecules
PubMed ID: 38657932
Doi: 10.1016/j.ijbiomac.2024.131766
Products & Services: Gene Synthesis   
Phenotypic characterization of sorghum seedlings and expression patterns of SNAC1 and DREB1A genes under water‑stress: an insight towards developing resilient cultivars
Authors: David Adedayo Animasaun · Khadijat Adetoun Adedoyin · Afeez Taiwo Bakare · Kabir Adeniran Mustapha · Mary Anuoluwapo Akinbobola · Kafayat Folasade Awujoola · Jonathan Toyin Ogunjobi
Journal: springerlink
Doi: 10.1007/s10722-024-01956-x
Products & Services: Gene Synthesis   
Human IgG Fc-engineering for enhanced plasma half-life, mucosal distribution and killing of cancer cells and bacteria
Authors: Stian Foss , Siri A Sakya, Leire Aguinagalde, Marta Lustig, Jutamas Shaughnessy, Ana Rita Cruz , Lisette Scheepmaker, Line Mathiesen, Fulgencio Ruso-Julve, Aina Karen Anthi, Torleif Tollefsrud Gjølberg
Journal: Nature Communications
PubMed ID: 38453922
Doi: 10.1038/s41467-024-46321-9
Products & Services: Gene Synthesis   
Decoding chromatin states by proteomic profiling of nucleosome readers
Authors: Saulius Lukauskas, Andrey Tvardovskiy, Nhuong V Nguyen , Mara Stadler, Peter Faull, Tina Ravnsborg, Bihter Özdemir Aygenli, Scarlett Dornauer, Helen Flynn, Rik G H Lindeboom, Teresa K Barth, Kevin Brockers, Stefanie M Hauck, Michiel Vermeulen, Ambrosius P Snijders, Christian L Müller, Peter A DiMaggio, Ole N Jensen, Robert Schneider, Till Bartke
Journal: Nature
PubMed ID: 38448585
Doi: 10.1038/s41586-024-07141-5
Products & Services: Codon Optimization   
Filamentous fungus-produced human monoclonal antibody provides protection against SARS-CoV-2 in hamster and non-human primate models
Authors: Franziska K Kaiser, Mariana Gonzalez Hernandez, Nadine Krüger, Ellinor Englund, Wenjuan Du, Anna Z Mykytyn, Mathijs P Raadsen, Mart M Lamers
Journal: Nature Communications
PubMed ID: 38485931
Doi: 10.1038/s41467-024-46443-0
Products & Services: Codon Optimization   
Alternative low-populated conformations prompt phase transitions in polyalanine repeat expansions
Authors: Rosa Antón, Miguel Á Treviño, David Pantoja-Uceda, Sara Félix, María Babu, Eurico J Cabrita, Markus Zweckstetter, Philip Tinnefeld, Andrés M Vera, Javier Oroz
Journal: Nature
PubMed ID: 38431667
Doi: 10.1038/s41467-024-46236-5
Products & Services: Gene Synthesis   

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