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Therapeutic circRNA aptamer alleviates PKR-associated osteoarthritis

Authors: Si-Kun Guo, Jinlong Suo, Youkui Huang, Xubin Yin, Jinghui Wang, Ling Li, Shaokun Sun, Weiguo Zou, Ling-Ling Chen

Journal: Science Bulletin

PubMed ID: 40021383

Doi: 10.1016/j.scib.2025.02.027

Whole-genome identification, evolutionary decipherment, and expression profiling analyses of alcohol dehydrogenase family members in soybean (Glycine max (L.) Merr.)

Authors: Liang Wang, Jing Wang, Xianqin Wen, Wenhua Dongchen, Yumei Dong, Yuanyuan Li, Quan Liang, Yaqiong Zhang

Journal: Plant Stress

Doi: 10.1016/j.stress.2025.100975

Products & Services: Custom DNA/RNA Oligos

Modifying recombinant purple acid phosphatase using computational design

Authors: Aishwarya Venkatramani, Montader Ali, Olga Predeina, Jennifer C Molloy, Pietro Sormanni, Elizabeth A H Hall

Journal: European Biophysics Journal

PubMed ID: 40650743

Doi: 10.1007/s00249-025-01779-3

Products & Services: Protein and Antibody Isolation

Systemic administration of an RNA binding and cell- penetrating antibody targets therapeutic RNA to multiple mouse models of cancer

Authors: Elias Quijano, Diana Martinez-Saucedo, Zaira Ianniello, Natasha Pinto-Medici, Madison Rackear, Haoting Chen, Luiz Lola-Pereira, Yanfeng Liu, Denise Hegan, Xinning Shan, Robert Tseng, Deanne Yugawa, Sumedha Chowdhury, Minsoo Khang, Jay P Singh, Rashed Abdullah, Perisa Azhir, Soki Kashima, Wendy S Woods, Nicholas Gosstola, Bruce C Turner, Stephen Squinto, Dale L Ludwig, Ranjit S Bindra, Marie E Robert, David A Braun, Pablo Perez Pinera, W Mark Saltzman, Luisa F Escobar-Hoyos, Peter M Glazer

Journal: Science Translation Medicine

PubMed ID: 40668891

Doi: 10.1126/scitranslmed.adk1868

Products & Services: Recombinant Antibody Expression Stable Cell Lines

CONSTANT PH MOLECULAR DYNAMICS OF PORCINE CIRCOVIRUS 2 CAPSID PROTEIN REVEALS A MECHANISM FOR CAPSID ASSEMBLY

Authors: Elvira Tarasova; Noriaki Okimoto; Shanshan Feng; Dmitry Nerukh; Reza Khayat; Makoto Taiji

Journal: Physical chemistry chemical physics : PCCP

PubMed ID: 34726674

Doi: 10.1039/d1cp02874j

Products & Services: Plasmid DNA Preparation

Deep Receptor Scanning Reveals General Sequence Constraints on GPCR Biosynthesis

Authors: Austin Tedman; Muskan Goel; Sohan Shah; Mathew K. Howard; Laura M. Chamness; Antonio Bonifasi; Ismalia Adams; Jacklyn M. Gallagher; Wesley D. Penn; Katarina Nemec; Eli F. McDonald; Brianna N. Corman; J. Paul Robinson; Carol Beth Post; Patricia L. Clark; M. Madan Babu; Aashish Manglik; Charles P. Kuntz; Willow Coyote-Maestas; Jonathan P. Schlebach

Journal: biorxiv

PubMed ID: 41000614

Doi: 10.1101/2025.09.19.677468

Synergistic chemo-immunotherapy for osteosarcoma via a pH-responsive multi-component nanoparticle system

Authors: Dapeng Li; Yuanfan Li; Jie Cang; Xianwen Yan; Feipeng Wu; Xuan Sun; Wenchao Zhang

Journal: Frontiers in pharmacology

PubMed ID: 40264674

Doi: 10.3389/fphar.2025.1584245

Products & Services: Peptide Synthesis

Resistance to oxyimino-cephalosporins conferred by an alternative mechanism of hydrolysis by the Acinetobacter -derived cephalosporinase-33 (ADC-33), a class C -lactamase present in carbapenem-resistant Acinetobacter baumannii (CR Ab )

Authors: Rachel A. Powers; Bradley J. Wallar; Hannah R. Jarvis; Zoe X. Ziegler; Cynthia M. June; Christopher R. Bethel; Andrea M. Hujer; Magdalena A. Taracila; Susan D. Rudin; Kristine M. Hujer; Fabio Prati; Emilia Caselli; Robert A. Bonomo

Journal: MBio

PubMed ID: 40377322

Doi: 10.1128/mbio.00287-25

Co‑treatment with triptolide and RSL3 induces hepatocellular carcinoma cell apoptosis and ferroptosis

Authors: Weixia Liu , Guodi Wu , Jing Wang , Shanshan Wu , Zhi Chen

Journal: Molecular Medicine Reports

PubMed ID: 40376993

Doi: 10.3892/mmr.2025.13567

Products & Services: Protein Electrophoresis and Western

The crystal structure of coronavirus RBD-TMPRSS2 complex provides basis for the discovery of therapeutic antibodies

Authors: Zhuoqian Zhao, Qi Yang, Xiaoce Liu, Mengfei Li, Yinkai Duan, Mingjuan Du, Anqi Zhou, Huanzhen Liu, Yujia He, Wei Wang, Yuchi Lu, Xiaoyu Zhang, Haofeng Wang, Xiuna Yang, Hongkai Zhang, Xinwen Chen, Zihe Rao, Haitao Yang

Journal: nature COMMUNICATION

PubMed ID: 40681508

Doi: 10.1038/s41467-025-62023-2

Products & Services: Protein and Antibody Isolation