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The two Gtsf paralogs in silkworms orthogonally activate their partner PIWI proteins for target cleavage

Authors: Natsuko Izumi, Keisuke Shoji, Takashi Kiuchi, Susumu Katsuma, Yukihide Tomari

Journal: RNA

PubMed ID: 36319089

Doi: 10.1261/rna.079380.122

Products & Services: Gene Fragments

Antagonist of sphingosine 1-phosphate receptor 3 reduces cold injury of rat donor hearts for transplantation

Authors: Eisho Kanemitsu, Xiangdong Zhao, Keiko Iwaisako, Asuka Inoue, Akihide Takeuchi, Shintaro Yagi, Hidetoshi Masumoto, Hiroaki Ohara, Motoyasu Hosokawa, Tomonari Awaya, Junken Aoki, Etsuro Hatano, Shinji Uemoto, Masatoshi Hagiwara

Journal: Transl Res

PubMed ID: 36347491

Doi: 10.1016/j.trsl.2022.11.003

Products & Services: Codon Optimization

IgA quantification as a good predictor of the neutralizing antibodies levels after vaccination against SARS-CoV-2

Authors: Lorena O Fernandes-Siqueira, Bruna G Sousa, Carlos E Cleto, Luciana S Wermelinger, Beatriz L L Caetano, Agatha R Pacheco, Simone M Costa, Fabio C L Almeida, Gustavo C Ferreira, Didier Salmon, Ada M B Alves, Andrea T Da Poian

Journal: J Clin Virol Plus

PubMed ID: 36349309

Doi: 10.1016/j.jcvp.2022.100121

Neutralization Epitopes in Trimer and Pentamer Complexes Recognized by Potent Cytomegalovirus-Neutralizing Human Monoclonal Antibodies

Authors: Yuanbao Ai, Changwen Wu, Ming Zhang, Dabbu Kumar Jaijyan, Tong Liu, Lipeng Zan, Nan Li, Wei Yu, Yueming Wang, Xiaohui Yuan, Chengming Li, Weihong Zheng, Hua Zhu, Hua-Xin Liao

Journal: Microbiol Spectr

PubMed ID: 36342276

Doi: 10.1128/spectrum.01393-22

Products & Services: Protein and Antibody Isolation

Seroprevalence of AAV neutralizing antibodies in males with Duchenne muscular dystrophy

Authors: Sumit Verma, Stella N Nwosu, Raj Razdan, Saila R Upadhyayula, Han C Phan, Abubakarr A Koroma, Isai Leguizamo, Natalie S Correa, Michael Kuipa, David Lee, Thomas H Vanderford, Matthew R Gardner

Journal: Hum Gene Ther

PubMed ID: 36324212

Doi: 10.1089/hum.2022.081

Products & Services: Plasmid DNA Preparation

Monoallelic de novo AJAP1 loss-of-function variants disrupt trans-synaptic control of neurotransmitter release

Authors: Simon Fr h; Sami Boudkkazi; Peter Koppensteiner; Vita Sereikaite; Li-Yuan Chen; Diego Fernandez-Fernandez; Pascal D. Rem; Daniel Ulrich; Jochen Schwenk; Ziyang Chen; Elodie Le Monnier; Thorsten Fritzius; Sabrina M. Innocenti; Val rie Besseyrias; Luca Trov ; Michal Stawarski; Emanuela Argilli; Elliott H. Sherr; Bregje van Bon; Erik-Jan Kamsteeg; Maria Iascone; Alba Pilotta; Maria R. Cutr ; Mahshid S. Azamian; Andr s Hern ndez-Garc a; Seema R. Lalani; Jill A. Rosenfeld; Xiaonan Zhao; Tiphanie P. Vogel; Herda Ona; Daryl A. Scott; Peter Scheiffele; Kristian Str mgaard; Mehdi Tafti; Martin Gassmann; Bernd Fakler; Ryuichi Shigemoto; Bernhard Bettler

Journal: SCIENCE ADVANCES

PubMed ID: 38985877

Doi: 10.1126/sciadv.adk5462

Products & Services: Gene Fragments

Immune Phenotypes and Target Antigens of Clonally Expanded Bone Marrow T Cells in Treatment-Naïve Multiple Myeloma

Authors: Carlotta Welters, María Fernanda Lammoglia Cobo, Christian Alexander Stein, Meng-Tung Hsu, Amin Ben Hamza, Livius Penter, Xiaojing Chen, Christopher Buccitelli, Oliver Popp, Philipp Mertins, Kerstin Dietze, Lars Bullinger, Andreas Moosmann, Eric Blanc, Dieter Beule, Armin Gerbitz, Julian Strobel, Holger Hackstein, Hans-Peter Rahn, Klaus Dornmair, Thomas Blankenstein, Leo Hansmann

Journal: Cancer Immunol Res

PubMed ID: 36122410

Doi: 10.1158/2326-6066.CIR-22-0434

Products & Services: Peptide Synthesis

An odorant receptor that senses four classes of musk compounds

Authors: Keiichi Yoshikawa, Jun Deguchi, Hu Jieying, Hsiu-Yi Lu, Hiroaki Matsunami

Journal: Curr Biol

PubMed ID: 36370695

Doi: 10.1016/j.cub.2022.10.038

Products & Services: Gene Synthesis

An insecticide target in mechanoreceptor neurons

Authors: Xiaomu Qiao , Xiaoyu Zhang , Zhendong Zhou , Lei Guo , Weiping Wu , Suhan Ma , Xinzhong Zhang , Craig Montell , Jia Huang

Journal: Sci Adv

PubMed ID: 36417522

Doi: 10.1126/sciadv.abq3132

Products & Services: Gene Synthesis Protein Electrophoresis and Western Polyclonal Antibody Services

DNA topology regulates PAM-Cas9 interaction and DNA unwinding to enable near-PAMless cleavage by thermophilic Cas9

Authors: Ya-Jing Shi , Min Duan , Jun-Mei Ding , Fan-Qi Wang , Li-Li Bi , Cai-Xiang Zhang , Yi-Zhou Zhang , Jun-Yi Duan , An-Hui Huang , Xin-Lin Lei , Hao Yin , Ying Zhang

Journal: Mol Cell

PubMed ID: 36272409

Doi: 10.1016/j.molcel.2022.09.032

Products & Services: Bacterial Expression Gene Synthesis