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COVID-19 adenovirus vector vaccine induces higher interferon and pro-inflammatory responses than mRNA vaccines in human PBMCs, macrophages and moDCs

Authors: Miao Jiang, Elina Väisänen, Pekka Kolehmainen, Moona Huttunen, Seppo Ylä-Herttuala, Seppo Meri, Pamela Österlund, Ilkka Julkunen

Journal: Vaccine

PubMed ID: 37142461

Doi: 10.1016/j.vaccine.2023.04.049

Products & Services: Molecular Biology Reagents

SLFN5-mediated chromatin dynamics sculpt higherorder DNA repair topology

Authors: Jinzhou Huang, Chenming Wu, Jake A Kloeber, Huanyao Gao, Ming Gao, Qian Zhu, Yiming Chang, Fei Zhao, Guijie Guo, Kuntian Luo, Haiming Dai, Sijia Liu, Qiru Huang, Wootae Kim, Qin Zhou, Shouhai Zhu, Zheming Wu, Xinyi Tu, Ping Yin, Min Deng, Liewei Wang, Jian Yuan, Zhenkun Lou

Journal: Molecular Cell

PubMed ID: 36854302

Doi: 10.1016/j.molcel.2023.02.004

Products & Services: CRISPR RNAs/Cas9 Proteins(INACTIVE)

Organization, genomic targeting, and assembly of three distinct SWI/SNF chromatin remodeling complexes in Arabidopsis

Authors: Wei Fu, Yaoguang Yu, Jie Shu , Zewang Yu, Yixiong Zhong, Tao Zhu, Zhihao Zhang, Zhenwei Liang, Yuhai Cui, Chen Chen , Chenlong Li

Journal: Plant Cell .

PubMed ID: 37062961

Doi: 10.1093/plcell/koad111

Products & Services: Protein Electrophoresis and Western

Direct Virus Gene Detection: A CRISPR/dCas9-Mediated Surface- Enhanced Raman Scattering Strategy with Enzyme-Catalyzed Signal Amplification

Authors: Ailing Su , Yuan Liu , Xiumian Cao , Junyi Zhao , Weiqing Xu , Chongyang Liang , Ping Li , Shuping Xu

Journal: Anal Chem .

PubMed ID: 36995921

Doi: 10.1021/acs.analchem.2c05384

Products & Services: Synthetic Guide RNA

Enhanced Degradation of Mutant -Derived Toxic Dipeptide Repeat Proteins by 20S Proteasome Activation Results in Restoration of Proteostasis and Neuroprotection

Authors: Allison S Vanecek, Jelena Mojsilovic-Petrovic, Robert G Kalb, Jetze J Tepe

Journal: ACS Chem Neurosci

PubMed ID: 37015082

Doi: 10.1021/acschemneuro.2c00732

Products & Services: Recombinant Proteins

Endoplasmic reticulum chaperone GRP78 participates in fluoride-induced autophagy in LS8 cells by regulating the IRE1-TRAF2-JNK pathway

Authors: Lin Zhao, Liyuan Wang, Han Wang, Tao Xi, Sijia Liu, Yang Li, Jianping Ruan, Yongqing Huang

Journal: Environ Toxicol

PubMed ID: 37070943

Doi: 10.1002/tox.23805

Products & Services: Molecular Biology Reagents

A triple amplification strategy using GR-5 DNAzyme as a signal medium for ultrasensitive detection of trace Pb based on CRISPR/Cas12a empowered electrochemical biosensor

Authors: Yuanyuan Yue, Songtao Wang, Qiang Jin, Nan An, Lina Wu, He Huang

Journal: Anal Chim Acta

PubMed ID: 37225346

Doi: 10.1016/j.aca.2023.341241

Products & Services: Protein and Antibody Isolation

Sustained secretion of human growth hormone from TheraCyte devices encapsulated with PiggyBac-engineered retinal pigment epithelium cells

Authors: Claudia R Cecchi, Sidsel Alsing, Gustavo P P Jesus, Enio A Zacarias, Lisbeth Kjaer, Michelle S Clement, Makiko Kumagai-Braesch, Thomas J Corydon, Paolo Bartolini, Cibele N Peroni, Lars Aagaard

Journal: Tissue Cell

PubMed ID: 37087908

Doi: 10.1016/j.tice.2023.102095

Products & Services: Gene Synthesis

LncRNA FLAIL affects alternative splicing and represses flowering in Arabidopsis

Authors: Yu Jin, Maxim Ivanov, Anna Nelson Dittrich, Andrew Dl Nelson, Sebastian Marquardt

Journal: EMBO J

PubMed ID: 37051749

Doi: 10.15252/embj.2022110921

Products & Services: Protein and Antibody Isolation

The functional and evolutionary impacts of human-specific deletions in conserved elements

Authors: James R Xue, Ava Mackay-Smith, Kousuke Mouri, Meilin Fernandez Garcia, Michael X Dong, Jared F Akers, Mark Noble, Xue Li, Kerstin Lindblad-Toh, Elinor K Karlsson, James P Noonan, Terence D Capellini, Kristen J Brennand, Ryan Tewhey, Pardis C Sabeti, Steven K Reilly

Journal: Science

PubMed ID: 37104592

Doi: 10.1126/science.abn2253

Products & Services: Gene Synthesis