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Engineering allorejection-resistant CAR-NKT cells from hematopoietic stem cells for off-the-shelf cancer immunotherapy

Authors: Yan-Ruide Li, Yang Zhou 1, Jiaji Yu, Yichen Zhu, Derek Lee, Enbo Zhu, Zhe Li, Yu Jeong Kim, Kuangyi Zhou, Ying Fang, Zibai Lyu, Yuning Chen, Yanxin Tian, Jie Huang, Xinjian Cen, Tiffany Husman, Jae Min Cho, Tzung Hsiai, Jin J Zhou, Pin Wang, Benjamin R Puliafito, Sarah M Larson, Lili Yang

Journal: Molecular Therapy

PubMed ID: 38584391

Doi: 10.1016/j.ymthe.2024.04.005

Products & Services: Gene Synthesis

Evidence that Xrn1 is in complex with Gcn1, and is required for full levels of eIF2αphosphorylation

Authors: Renuka Shanmugam, Reuben Anderson, Anja H Schiemann, Evelyn Sattlegger

Journal: The Biochemical journal

PubMed ID: 38440860

Doi: 10.1042/BCJ20220531

Products & Services: PCR Cloning and Subcloning

Decoding the blueprint of receptor binding by filoviruses through large-scale binding assays and machine learning

Authors: Gorka Lasso; Michael Grodus; Estefania Valencia; Veronica DeJesus; Eliza Liang; Isabel Delwel; Rob H. Bortz; Dmitry Lupyan; Hanna Y. Ehrlich; Adrian A. Castellanos; Andrea Gazzo; Heather L. Wells; Supaporn Wacharapluesadee; Alexandre Tremeau-Bravard; Janine F.R. Seetahal; Tom Hughes; Jimmy Lee; Mei-Ho Lee; Anna R. Sjodin; Marike Geldenhuys; Marinda Mortlock; Isamara Navarrete-Macias; Kirsten Gilardi; Michael R. Willig; Alessandra F.D. Nava; Elisabeth H. Loh; Makda Asrat; Tierra Smiley-Evans; Walter S. Magesa; Sijali Zikankuba; David Wolking; Gerardo Suz n; Rafael Ojeda-Flores; Christine V.F. Carrington; Ariful Islam; Jonathan H. Epstein; Wanda Markotter; Christine K. Johnson; Tracey Goldstein; Barbara A. Han; Jonna A.K. Mazet; Rohit K. Jangra; Kartik Chandran; Simon J. Anthony

Journal: Cell Host & Microbe

PubMed ID: 39818205

Doi: 10.1016/j.chom.2024.12.016

Products & Services: Protein and Antibody Isolation

Deciphering the unique autoregulatory mechanisms and substrate specificity of the understudied DCLK3 kinase linked to neurodegenerative diseases

Authors: Jason D. Lu; Peng Zhao; Anup Prasad; Neha Gupta; Nathan Gravel; Tej Shidhaye; Lance Wells; Samiksha Katiyar; Natarajan Kannan

Journal: The Journal of Biological Chemistry

PubMed ID: 40902973

Doi: 10.1016/j.jbc.2025.110664

Virtual screening and evaluation of bioactive peptides from Haliotis discus hannai as potential HMGCR inhibitors for hyperlipidemia treatment

Authors: Kun Qiao; Lina Liu; Yihui Chen; Qiongmei Huang; Bei Chen; Jingna Wu; Wenmei Huang; Zhiyu Liu

Journal: Frontiers in nutrition

PubMed ID: 39811675

Doi: 10.3389/fnut.2024.1525768

Products & Services: Peptide Synthesis

Virtual screening and evaluation of bioactive peptides from Haliotis discus hannai as potential HMGCR inhibitors for hyperlipidemia treatment

Authors: Kun Qiao; Lina Liu; Yihui Chen; Qiongmei Huang; Bei Chen; Jingna Wu; Wenmei Huang; Zhiyu Liu

Journal: Frontiers in nutrition

PubMed ID: 39811675

Doi: 10.3389/fnut.2024.1525768

Products & Services: Peptide Synthesis

Genetic mechanisms underlying the structural elaboration and dissemination of viral internal ribosomal entry sites

Authors: Irina S Abaeva, Tatyana V Pestova, Christopher U T Hellen

Journal: biorxiv

PubMed ID: 38883778

Doi: 10.1093/nar/gkag629

Products & Services: Gene Synthesis

Flow Cytometry-Based Measurement of Antibodies Specific for Cell Surface-Expressed Folded SARS-CoV-2 Receptor-Binding Domains

Authors: Al Nasar Ahmed Sehgal, Jera Safran, Bernhard Kratzer, Pia Gattinger, Robert B Stieger, Laszlo Musiejovsky, Doris Trapin, Paul Ettel, Ulrike Körmöczi, Arno Rottal, Kristina Borochova, Yulia Dorofeeva, Inna Tulaeva, Milena Weber, Katharina Grabmeier-Pfistershammer, Thomas Perkmann, Ursula Wiedermann, Rudolf Valenta, Winfried F Pickl

Journal: Vaccines (Basel)

PubMed ID: 38675759

Doi: 10.3390/vaccines12040377

Products & Services: Protein and Antibody Isolation Recombinant Proteins Protein Electrophoresis and Western

Cancer-associated polybromo-1 bromodomain 4 missense variants variably impact bromodomain ligand binding and cell growth suppression

Authors: Karina L. Bursch; Christopher J. Goetz; Guanming Jiao; Raymundo Nu ez; Michael D. Olp; Alisha Dhiman; Mallika Khurana; Michael T. Zimmermann; Raul A. Urrutia; Emily C. Dykhuizen; Brian C. Smith

Journal: The Journal of Biological Chemistry

PubMed ID: 38460939

Doi: 10.1016/j.jbc.2024.107146

Products & Services: Protein and Antibody Isolation

MCT4 and CD147 colocalize with MMP14 in invadopodia and support matrix degradation and invasion by breast cancer cells

Authors: Signe Meng, Ester E Sørensen, Muthulakshmi Ponniah, Jeppe Thorlacius-Ussing, Roxane Crouigneau, Tanja Larsen, Magnus T Borre, Nicholas Willumsen, Mette Flinck, Stine F Pedersen

Journal: J Cell Sci

PubMed ID: 38661040

Doi: 10.1242/jcs.261608

Products & Services: Protein and Antibody Isolation