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Identification of key genes affecting ventilator-induced diaphragmatic dysfunction in diabetic mice

Authors: Rongchun Xing, Haibo Yu, Jiangtao Yu, Rong Zeng, Zhijun Xiang, Haoli Ma, Gang Li, Yan Zhao

Journal: Front Genet

PubMed ID: 38784031

Doi: 10.3389/fgene.2024.1387688

Products & Services: Gene Synthesis

The three-dimensional structure of DapE from Enterococcus faecium reveals new insights into DapE/ArgE subfamily ligand specificity

Authors: Manuel Terrazas-López, Lilian González-Segura, Adelaida Díaz-Vilchis, Kelly Annecy Aguirre-Mendez, Naún Lobo-Galo, Alejandro Martínez-Martínez, Ángel G Díaz-Sánchez

Journal: Int J Biol Macromol

PubMed ID: 38740150

Doi: 10.1016/j.ijbiomac.2024.132281

Products & Services: Mutagenesis Services

Overexpression of PEX14 results in mistargeting to mitochondria, accompanied by organelle fragmentation and clustering in human embryonic kidney cells

Authors: Renate L M Jansen, Rinse de Boer, Eline M F de Lange, Janet Koster, Rifka Vlijm, Hans R Waterham, Ida J van der Klei

Journal: Biochim Biophys Acta Mol Cell Res

PubMed ID: 38762172

Doi: 10.1016/j.bbamcr.2024.119754

Products & Services: Molecular Biology Reagents

Deep mutational scanning reveals a correlation between degradation and toxicity of thousands of aspartoacylase variants

Authors: Martin Grønbæk-Thygesen, Vasileios Voutsinos, Kristoffer E. Johansson, Thea K. Schulze, Matteo Cagiada, Line Pedersen, Lene Clausen, Snehal Nariya, Rachel L. Powell, Amelie Stein, Douglas M. Fowler, Kresten Lindorff-Larsen & Rasmus Hartmann-Petersen

Journal: Nat Commun

PubMed ID: 38740822

Doi: 10.1038/s41467-024-48481-0

Products & Services: Mutagenesis Services

Catalytic Mechanism of SARS-CoV-2 3-Chymotrypsin-Like Protease as Determined by Steady-State and Pre-Steady-State Kinetics

Authors: Jiyun Zhu; Alexandria M. Kemp; Bala C. Chenna; Vivek Kumar; Andrew Rademacher; Sangho Yun; Arthur Laganowsky; Thomas D. Meek

Journal: ACS catalysis

PubMed ID: 39722883

Doi: 10.1021/acscatal.4c04695

Nuclear Magnetic Resonance based fragment screen of the E3 ligase Fem 1 homolog B

Authors: Jade M. Katinas; Kangsa Amporndanai; Ashley J. Taylor; Kristie L. Rose; Peter C. Gareiss; Roberto A. Crespo; Jason Phan; Alex G. Waterson; Stephen W. Fesik

Journal: Protein science : a publication of the Protein Society

PubMed ID: 41229306

Doi: 10.1002/pro.70365

Single-molecule assay guided crRNA optimization enhances specific microRNA detection by CRISPR-Cas12a

Authors: Kaizhao Chen, Wenjun Sun, Mingtian Zhong, Jiaqi Xie, Yongkun Huo, Xiuqi Lu, Ziting Chen, Bo Sun, Xingxu Huang, Xinjie Wang， Ming Liu , Xiaodong Ma, Peixiang Ma

Journal: Sensors and Actuators B: Chemical

Doi: 10.1016/j.snb.2024.135389

Products & Services: Protein Electrophoresis and Western

Computational design of generalist cyclopropanases with stereodivergent selectivity

Authors: Zhuofan Shen; Mary G. Siriboe; Xinkun Ren; Thakshila Dayananda; Jermaine L. Jenkins; Sagar D. Khare; Rudi Fasan

Journal: Nature Communications

PubMed ID: 41587967

Doi: 10.1038/s41467-026-68327-1