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Preclinical development of a bispecific TNFα/IL-23 neutralising domain antibody as a novel oral treatment for inflammatory bowel disease
Authors: Kevin J Roberts, Marion F Cubitt, Timothy M Carlton, Lurdes Rodrigues-Duarte, Luana Maggiore, Ray Chai, Simon Clare, Katherine Harcourt, Thomas T MacDonald, Keith P Ray, Anna Vossenkämper, Michael R West, J Scott Crowe
Journal: Sci Rep
PubMed ID: 34593832
Doi: 10.1038/s41598-021-97236-0
Products & Services: Monoclonal Antibody Services   
Conformational rearrangements enable iterative backbone N-methylation in RiPP biosynthesis
Authors: Fredarla S Miller, Kathryn K Crone, Matthew R Jensen, Sudipta Shaw, William R Harcombe, Mikael H Elias, Michael F Freeman
Journal: Nat Commun
PubMed ID: 34504067
Doi: 10.1038/s41467-021-25575-7
Products & Services: Bacterial Expression   
Structural insights into the activation of human calcium-sensing receptor
Authors: Xiaochen Chen, Lu Wang, Qianqian Cui, Zhanyu Ding, Li Han, Yongjun Kou, Wenqing Zhang, Haonan Wang, Xiaomin Jia, Mei Dai, Zhenzhong Shi, Yuying Li, Xiyang Li, Yong Geng
Journal: Elife
PubMed ID: 34467854
Doi: 10.7554/eLife.68578
Products & Services: Catalog Peptides   
Molecular basis for ATPase-powered substrate translocation by the Lon AAA+ protease
Authors: Shanshan Li, Kan-Yen Hsieh, Shih-Chieh Su, Grigore D Pintilie, Kaiming Zhang, Chung-I Chang
Journal: J Biol Chem
PubMed ID: 34563541
Doi: 10.1016/j.jbc.2021.101239
Newt regeneration genes regulate Wingless signaling to restore patterning in eye
Authors: Abijeet Singh Mehta, Prajakta Deshpande, Anuradha Venkatakrishnan Chimata, Panagiotis A Tsonis, Amit Singh
Journal: iScience
PubMed ID: 34746690
Doi: 10.1016/j.isci.2021.103166
Products & Services: ORF cDNA Clones/MolecularCloud   
Transient Electrostatic Interactions between Fcp1 and Rap74 Bias the Conformational Ensemble of the Complex with Minimal Impact on Binding Affinity
Authors: Victor A Prieto, Kevin E W Namitz, Scott A Showalter
Journal: J Phys Chem B
PubMed ID: 34550709
Doi: 10.1021/acs.jpcb.1c05131
Products & Services: Catalog Peptides   
Immunogenicity and potential protection of DNA vaccine of Leishmania martiniquensis against Leishmania infection in mice
Authors: Thuntawat Aunguldee, Orapin Gerdprasert, Piyatida Tangteerawatana, Amporn Jariyapongskul, Saovanee Leelayoova, Benjamas Thanomsub Wongsatayanon
Journal: J Infect Dev Ctries
PubMed ID: 34669604
Doi: 10.3855/jidc.14472
Products & Services: Gene Synthesis   
Lymph Node-Targeted Synthetically Glycosylated Antigen Leads to Antigen-Specific Immunological Tolerance
Authors: Chitavi D Maulloo, Shijie Cao, Elyse A Watkins, Michal M Raczy, Ani S Solanki, Mindy Nguyen, Joseph W Reda, Ha-Na Shim, D Scott Wilson, Melody A Swartz, Jeffrey A Hubbell
Journal: Front Immunol
PubMed ID: 34630389
Doi: 10.3389/fimmu.2021.714842
Products & Services: Peptide Synthesis   
Microbial Biosynthesis of L-Malic Acid and Related Metabolic Engineering Strategies: Advances and Prospects
Authors: Zhen Wei, Yongxue Xu, Qing Xu, Wei Cao, He Huang, Hao Liu
Journal: Front Bioeng Biotechnol
PubMed ID: 34660563
Doi: 10.3389/fbioe.2021.765685
Products & Services: Gene Synthesis   
The Isolated in Utero Environment Is Conducive to the Emergence of RNA and DNA Virus Variants
Authors: Daniel Udenze, Ivan Trus, Henry Munyanduki, Nathalie Berube, Uladzimir Karniychuk
Journal: Viruses
PubMed ID: 34578408
Doi: 10.3390/v13091827
Products & Services: Gene Synthesis   

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