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Potent monoclonal antibodies neutralize Omicron sublineages and other SARS-CoV-2 variants

Authors: Zhaochun Chen, Peng Zhang, Yumiko Matsuoka, Yaroslav Tsybovsky, Kamille West, Celia Santos, Lisa F Boyd, Hanh Nguyen, Anna Pomerenke, Tyler Stephens, Adam S Olia, Baoshan Zhang, Valeria De Giorgi, Michael R Holbrook, Robin Gross, Elena Postnikova, Nicole L Garza, Reed F Johnson, David H Margulies, Peter D Kwong, Harvey J Alter, Ursula J Buchholz, Paolo Lusso, Patrizia Farci

Journal: Cell Rep

PubMed ID: 36302375

Doi: 10.1016/j.celrep.2022.111528

Products & Services: Mammalian Expression

Enhanced and Potency of a T Cell Epitope in the Ebola Virus Glycoprotein Following Amino Acid Replacement at HLA-A*02:01 Binding Positions

Authors: Sylvie Chabot, Yusra Gimie, Karam Obeid, Jaekwan Kim, Clement A Meseda, Krishnamurthy Konduru, Gerardo Kaplan, Li Sheng Fowler, Jerry P Weir, Keith Peden, Marian E Major

Journal: J Virol

PubMed ID: 36069549

Doi: 10.1128/jvi.01166-21

Products & Services: Gene Synthesis

An albumin-angiotensin converting enzyme 2-based SARS-CoV-2 decoy with FcRn-driven half-life extension

Authors: Elisabeth Fuchs, Imke Rudnik-Jansen, Anders Dinesen, Denis Selnihhin, Ole Aalund Mandrup, Kader Thiam, Jørgen Kjems, Finn Skou Pedersen, Kenneth A Howard

Journal: Acta Biomater

PubMed ID: 36162760

Doi: 10.1016/j.actbio.2022.09.048

Products & Services: Plasmid DNA Preparation

miR-3651 Participates in the Growth Cycle of Hepatocellular Carcinoma Cells and Promotes the Malignant Metastasis via the PI3K/AKT/mTOR Signalling Pathway

Authors: Yawei Liu, Litian Hu, Qinqiang Liu, Jing Ye, Jianping Zhang

Journal: J Oncol

PubMed ID: 36245984

Doi: 10.1155/2022/5744999

Products & Services: Custom Vector Construction

Improving radiotherapy in immunosuppressive microenvironments by targeting complement receptor C5aR1

Authors: Callum Beach; David MacLean; Dominika Majorova; Stavros Melemenidis; Dhanya K. Nambiar; Ryan K. Kim; Gabriel N. Valbuena; Silvia Guglietta; Carsten Krieg; Mahnaz Darvish-Damavandi; Tatsuya Suwa; Alistair Easton; Lily V.S. Hillson; Ashley K. McCulloch; Ross K. McMahon; Kathryn Pennel; Joanne Edwards; Sean M. O Cathail; Campbell S. Roxburgh; Enric Domingo; Eui Jung Moon; Dadi Jiang; Yanyan Jiang; Qingyang Zhang; Albert C. Koong; Trent M. Woodruff; Edward E. Graves; Tim Maughan; Simon J.A. Buczacki; Manuel Stucki; Quynh-Thu Le; Simon J. Leedham; Amato J. Giaccia; Monica M. Olcina

Journal: The Journal of clinical investigation

PubMed ID: 37824211

Doi: 10.1172/JCI168277

Products & Services: Custom Vector Construction

Prohormone cleavage prediction uncovers a non-incretin anti-obesity peptide

Authors: Laetitia Coassolo; Niels B. Danneskiold-Sams e; Quennie Nguyen; Amanda Wiggenhorn; Meng Zhao; David Cheng-Hao Wang; David Toomer; Jameel Lone; Yichao Wei; Aayan Patel; Irene Liparulo; Deniz Kavi; Lianna W. Wat; Saranya Chidambaranathan Reghupaty; Julie Jae Kim; Tina Asemi; Ewa Bielczyk-Maczynska; Veronica L. Li; Maria Dolores Moya-Garzon; Nicole A. J. Krentz; Andreas Stahl; Danny Hung-Chieh Chou; Liqun Luo; Katrin J. Svensson

Journal: Nature

PubMed ID: 40044869

Doi: 10.1038/s41586-025-08683-y

H2B Lys34 Ubiquitination Induces Nucleosome Distortion to Stimulate Dot1L Activity

Authors: Huasong Ai , Maoshen Sun , Aijun Liu , Zixian Sun , Tingting Liu , Lin Cao , Lujun Liang , Qian Qu , Zichen Li , Zhiheng Deng , Zebin Tong , Guochao Chu , Xiaolin Tian , Haiteng Deng , Suwen Zhao , Jia-Bin Li , Zhiyong Lou , Lei Liu

Journal: Nat Chem Biol

PubMed ID: 35739357

Doi: 10.1038/s41589-022-01067-7

Products & Services: Gene Synthesis

The SOS response-associated peptidase (SRAP) domain of YedK catalyzes ring opening of abasic sites and reversal of its DNA–protein cross-link

Authors: Katherine A Paulin , David Cortez , Brandt F Eichman

Journal: J Biol Chem

PubMed ID: 35934051

Doi: 10.1016/j.jbc.2022.102307

Products & Services: Peptide Synthesis

Guide RNA engineering enables efficient CRISPR editing with a miniature Syntrophomonas palmitatica Cas12f1 nuclease

Authors: Yujue Wang , Yannan Wang ， Deng Pan , Haopeng Yu , Yifei Zhang , Weizhong Chen , Fan Li , Zhaowei Wu , Quanjiang Ji

Journal: Cell Rep

PubMed ID: 36170834

Doi: doi.org/10.1016/j.celrep.2022.111418

Products & Services: Molecular Biology Reagents

Nilaparvata lugens salivary protein NlG14 triggers defense response in plants

Authors: Haoli Gao , Jianzheng Zou , Xumin Lin , Huihui Zhang , Na Yu , Zewen Liu

Journal: J Exp Bot

PubMed ID: 36056768

Doi: 10.1093/jxb/erac354

Products & Services: Protein and Antibody Isolation