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Molnupiravir and Nirmatrelvir-Ritonavir: Oral COVID Antiviral Drugs
Authors: Louis D Saravolatz, Shawn Depcinski, Mamta Sharma
Journal: Clin Infect Dis
PubMed ID: 35245942
Doi: 10.1093/cid/ciac180
Adaptive translational reprogramming of metabolism limits the response to targeted therapy in BRAF melanoma
Authors: Lorey K Smith, Tiffany Parmenter, Margarete Kleinschmidt, Eric P Kusnadi, Jian Kang, Claire A Martin, Peter Lau, Riyaben Patel, Julie Lorent, David Papadopoli, Anna Trigos, Teresa Ward, Aparna D Rao, Emily J Lelliott, Karen E Sheppard, David Goode, Rodney J Hicks, Tony Tiganis, Kaylene J Simpson, Ola Larsson, Benjamin Blythe, Carleen Cullinane, Vihandha O Wickramasinghe, Richard B Pearson, Grant A McArthur
Journal: Nat Commun
PubMed ID: 35232962
Doi: 10.1038/s41467-022-28705-x
Products & Services: Mutant Libraries   
Glycosite-deleted mRNA of SARS-CoV-2 spike protein as a broad-spectrum vaccine
Authors: Chung-Yi Wu, Cheng-Wei Cheng, Chih-Chuan Kung, Kuo-Shiang Liao, Jia-Tsrong Jan, Che Ma, Chi-Huey Wong
Journal: Proc Natl Acad Sci U S A
PubMed ID: 35149556
Doi: 10.1073/pnas.2119995119
Products & Services: Codon Optimization   
Heat Shock Protein A6 Is Especially Involved in Enterovirus 71 Infection
Authors: Jiaoyan Jia, Ge Liu, Jianfeng Zhong, Ran Yan, Xun Song, Kai Zheng, Zhe Ren, Zhendan He, Qinchang Zhu
Journal: Front Microbiol
PubMed ID: 35308396
Doi: 10.3389/fmicb.2022.865644
Products & Services: Proteins, Expression, Isolation and Analysis   
Pervasive translation in
Authors: Carol Smith, Jill G Canestrari, Archer J Wang, Matthew M Champion, Keith M Derbyshire, Todd A Gray, Joseph T Wade
Journal: Elife
PubMed ID: 35343439
Doi: 10.7554/eLife.73980
Products & Services: Proteins, Expression, Isolation and Analysis   
Characterization of UDP-glycosyltransferase family members reveals how major flavonoid glycoside accumulates in the roots of Scutellaria baicalensis
Authors: Tianlin Pei, Mengxiao Yan, Tian Li, Xiaoqiang Li, Yijia Yin, Mengying Cui, Yumin Fang, Jie Liu, Yu Kong, Ping Xu, Qing Zhao
Journal: BMC Genomics
PubMed ID: 35232374
Doi: 10.1186/s12864-022-08391-1
Products & Services: GenParts™ DNA Fragments   
Generation of Gal-enhanced bifunctional tumor vaccine
Authors: Jian He, Yu Huo, Zhikun Zhang, Yiqun Luo, Xiuli Liu, Qiaoying Chen, Pan Wu, Wei Shi, Tao Wu, Chao Tang, Huixue Wang, Lan Li, Xiyu Liu, Yong Huang, Yongxiang Zhao, Lu Gan, Bing Wang, Liping Zhong
Journal: Acta Pharm Sin B
PubMed ID: 35865091
Doi: 10.1016/j.apsb.2022.03.002
Products & Services: Custom Vector Construction   
Robust, Durable Gene Activation In Vivo via mRNA-Encoded Activators
Authors: Jared P Beyersdorf, Swapnil Bawage, Nahid Iglesias, Hannah E Peck, Ryan A Hobbs, Jay A Wroe, Chiara Zurla, Charles A Gersbach, Philip J Santangelo
Journal: ACS Nano
PubMed ID: 35357116
Doi: 10.1021/acsnano.1c10631
Products & Services: Gene Synthesis   
Humanization of a strategic CD3 epitope enables evaluation of clinical T-cell engagers in a fully immunocompetent in vivo model
Authors: Julie A Zorn, Matthew L Wheeler, Ralston M Barnes, Jim Kaberna, Winse Morishige, Marek Harris, Richard Y-C Huang, Jack Lohre, Yu Ching Chang, Bryant Chau, Kathleen Powers, Ian Schindler, Naveen Neradugomma, Winston Thomas, Xiaoyun Liao, Yinhan Zhou, Sean M West, Feng Wang, Srikanth Kotapati, Guodong Chen, Sayumi Yamazoe, Anastasia Kosenko, Gavin Dollinger, Tim Sproul, Arvind Rajpal, Pavel Strop
Journal: Sci Rep
PubMed ID: 35241687
Doi: 10.1038/s41598-022-06953-7
Products & Services: Plasmid DNA Preparation   
Regulator of Actin-Based Motility (RoaM) Downregulates Actin Tail Formation by Rickettsia rickettsii and Is Negatively Selected in Mammalian Cell Culture
Authors: Adam M Nock, Tina R Clark, Ted Hackstadt
Journal: MBio
PubMed ID: 35285700
Doi: 10.1128/mbio.00353-22
Products & Services: Gene Synthesis   

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