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Actin polymerisation and crosslinking drive left-right asymmetry in single cell and cell collectives

Authors: Yee Han Tee, Wei Jia Goh, Xianbin Yong, Hui Ting Ong, Jinrong Hu, Ignacius Yan Yun Tay, Shidong Shi, Salma Jalal, Samuel F H Barnett, Pakorn Kanchanawong, Wenmao Huang, Jie Yan, Yong Ann Ben Lim, Visalatchi Thiagarajan, Alex Mogilner, Alexander D Bershadsky

Journal: Nat Commun

PubMed ID: 36774346

Doi: 10.1038/s41467-023-35918-1

Products & Services: Protein and Antibody Isolation

Establishment and validation of a plasma oncofetal chondroitin sulfated proteoglycan for pan-cancer detection

Authors: Pei-Fen Zhang, Zi-Yi Wu, Wen-Bin Zhang, Yong-Qiao He, Kexin Chen, Tong-Min Wang, Haixin Li, Hong Zheng, Dan-Hua Li, Da-Wei Yang, Ting Zhou, Chang-Mi Deng, Ying Liao, Wen-Qiong Xue, Lian-Jing Cao, Xi-Zhao Li, Jiang-Bo Zhang, Si-Qi Dong, Fang Wang, Mei-Qi Zheng, Wen-Li Zhang, Jianbing Mu, Wei-Hua Jia

Journal: Nat Commun

PubMed ID: 36746966

Doi: 10.1038/s41467-023-36374-7

Products & Services: Protein and Antibody Isolation

Cholesterol esters form supercooled lipid droplets whose nucleation is facilitated by triacylglycerols

Authors: Calvin Dumesnil, Lauri Vanharanta, Xavier Prasanna, Mohyeddine Omrane, Maxime Carpentier, Apoorva Bhapkar, Giray Enkavi, Veijo T Salo, Ilpo Vattulainen, Elina Ikonen, Abdou Rachid Thiam

Journal: Nat Commun

PubMed ID: 36807572

Doi: 10.1038/s41467-023-36375-6

Products & Services: Codon Optimization

Functional analysis of 110 phosphorylation sites on the circadian clock protein FRQ identifies clusters determining period length and temperature compensation

Authors: Bin Wang, Elizabeth-Lauren Stevenson, Jay C Dunlap

Journal: G3 (Bethesda)

PubMed ID: 36537198

Doi: 10.1093/g3journal/jkac334

Products & Services: Gene Synthesis

A cercarial invadolysin interferes with the host immune response and facilitates infection establishment of Schistosoma mansoni

Authors: Jacob R Hambrook, Patrick C Hanington

Journal: PLoS Pathog

PubMed ID: 36730464

Doi: 10.1371/journal.ppat.1010884

Products & Services: Polyclonal Antibody Services

Multi-omic screening of invasive GBM cells in engineered biomaterials and patient biopsies reveals targetable transsulfuration pathway alterations

Authors: Joseph H Garcia, Erin A Akins, Saket Jain, Kayla J Wolf, Jason Zhang, Nikita Choudhary, Meeki Lad, Poojan Shukla, Sabraj Gill, Will Carson, Luis Carette, Allison Zheng, Sanjay Kumar, Manish K Aghi

Journal: biorxiv

PubMed ID: 36865128

Doi: 10.1101/2023.02.23.529575

Products & Services: Peptide Synthesis

SARS-CoV-2 Main Protease Targets Host Selenoproteins and Glutathione Biosynthesis for Knockdown via Proteolysis, Potentially Disrupting the Thioredoxin and Glutaredoxin Redox Cycles

Authors: Ignacio A Gallardo, Daniel A Todd, Stella T Lima, Jonathan R Chekan, Norman H Chiu, Ethan Will Taylor

Journal: Antioxidants (Basel)

PubMed ID: 36978807

Doi: 10.3390/antiox12030559

Products & Services: Protein and Antibody Isolation

Retinoblastoma Expression and Targeting by CDK4/6 Inhibitors in Small Cell Lung Cancer

Authors: Gary Wildey, Ashley M Shay, Karen S McColl, Suzy Yoon, Mohammad A Shatat, Ahmad Perwez, Kyle B Spainhower, Adam M Kresak, MaryBeth Lipka, Michael Yang, Mohadese Behtaj, Pingfu Fu, Asrar Alahmadi, Wadad Mneimneh, Ata Abbas, Afshin Dowlati

Journal: Mol Cancer Ther

PubMed ID: 36399634

Doi: 10.1158/1535-7163.MCT-22-0365

Products & Services: Molecular Biology Reagents

Xeno interactions between MHC-I proteins and molecular chaperones enable ligand exchange on a broad repertoire of HLA allotypes

Authors: Yi Sun, Georgia F Papadaki, Christine A Devlin, Julia N Danon, Michael C Young, Trenton J Winters, George M Burslem, Erik Procko, Nikolaos G Sgourakis

Journal: Sci Adv

PubMed ID: 36827371

Doi: 10.1126/sciadv.ade7151

Products & Services: Molecular Biology Reagents

Gestational palmitic acid suppresses embryonic GATA-binding protein 4 signaling and causes congenital heart disease

Authors: Rui Zhao, Li Cao, Wen-Jun Gu, Lei Li, Zhong-Zhong Chen, Jie Xiang, Ze-Yu Zhou, Bo Xu, Wei-Dong Zang, Xiang-Yu Zhou, Jing Cao, Kun Sun, Jian-Yuan Zhao

Journal: Cell Rep Med

PubMed ID: 36809766

Doi: 10.1016/j.xcrm.2023.100953

Products & Services: Protein Electrophoresis and Western