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Epitopes in the Glycosylphosphatidylinositol Attachment Signal Peptide of Trypanosoma cruzi Mucin Proteins Generate Robust but Delayed and Nonprotective CD8+ T Cell Responses

Authors: Molly E Bunkofske, Natasha Perumal, Brooke White, Eva-Maria Strauch, Rick Tarleton

Journal: J Immunol

PubMed ID: 36603035

Doi: 10.4049/jimmunol.2200723

Products & Services: Molecular Biology Reagents

Structural mechanism for inhibition of PP2A-B56α and oncogenicity by CIP2A

Authors: Karolina Pavic, Nikhil Gupta, Judit Domènech Omella, Rita Derua, Anna Aakula, Riikka Huhtaniemi, Juha A Määttä, Nico Höfflin, Juha Okkeri, Zhizhi Wang, Otto Kauko, Roosa Varjus, Henrik Honkanen, Daniel Abankwa, Maja Köhn, Vesa P Hytönen, Wenqing Xu, Jakob Nilsson, Rebecca Page, Veerle Janssens, Alexander Leitner, Jukka Westermarck

Journal: Nat Commun

PubMed ID: 36854761

Doi: 10.1038/s41467-023-36693-9

Products & Services: Molecular Biology Reagents

The molecular chaperone cysteine string protein is required for monomeric SNARE proteins to assemble in trans-complexes during human sperm acrosomal exocytosis†

Authors: Karina Flores-Montero, María Victoria Berberián, Luis Segundo Mayorga, Claudia Nora Tomes, María Celeste Ruete

Journal: Biol Reprod

PubMed ID: 36308432

Doi: 10.1093/biolre/ioac196

Products & Services: Protein and Antibody Isolation

Characterization of a TatA/TatB binding site on the TatC component of the twin arginine translocase

Authors: Emmanuele Severi, Mariana Bunoro Batista, Adelie Lannoy, Phillip J Stansfeld, Tracy Palmer

Journal: Microbiology (Reading)

PubMed ID: 36790402

Doi: 10.1099/mic.0.001298

Products & Services: Protein and Antibody Isolation

CriSNPr, a single interface for the curated and de novo design of gRNAs for CRISPR diagnostics using diverse Cas systems

Authors: Asgar H Ansari, Manoj Kumar, Sajal Sarkar, Souvik Maiti, Debojyoti Chakraborty

Journal: Elife

PubMed ID: 36752591

Doi: 10.7554/eLife.77976

Products & Services: Protein and Antibody Isolation

Dynamic states of eIF6 and SDS variants modulate interactions with uL14 of the 60S ribosomal subunit

Authors: Jonah Elliff, Aparna Biswas, Poonam Roshan, Sahiti Kuppa, Angela Patterson, Jenna Mattice, Mathivanan Chinnaraj, Ryan Burd, Sarah E Walker, Nicola Pozzi, Edwin Antony, Brian Bothner, Sofia Origanti

Journal: Nucleic Acids Res

PubMed ID: 36651285

Doi: 10.1093/nar/gkac1266

Products & Services: Protein and Antibody Isolation

Broadly neutralizing SARS-CoV-2 antibodies through epitope-based selection from convalescent patients

Authors: Romain Rouet, Jake Y Henry, Matt D Johansen, Meghna Sobti, Harikrishnan Balachandran, David B Langley, Gregory J Walker, Helen Lenthall, Jennifer Jackson, Stephanie Ubiparipovic, Ohan Mazigi, Peter Schofield, Deborah L Burnett, Simon H J Brown, Marianne Martinello, Bernard Hudson, Nicole Gilroy, Jeffrey J Post, Anthony Kelleher, Hans-Martin Jäck, Christopher C Goodnow, Stuart G Turville, William D Rawlinson, Rowena A Bull, Alastair G Stewart, Philip M Hansbro, Daniel Christ

Journal: Nat Commun

PubMed ID: 36755042

Doi: 10.1038/s41467-023-36295-5

Products & Services: Protein and Antibody Isolation

Single-Molecule Interconversion between Chiral Configurations of Boronate Esters Observed in a Nanoreactor

Authors: Xiaoyu Du, Shanyu Zhang, Liying Wang, Yuqin Wang, Pingping Fan, Wendong Jia, Panke Zhang, Shuo Huang

Journal: ACS Nano

PubMed ID: 36655995

Doi: 10.1021/acsnano.2c11286

Products & Services: Plasmid DNA Preparation

The activation mechanism and antibody binding mode for orphan GPR20

Authors: Xi Lin, Shan Jiang, Yiran Wu, Xiaohu Wei, Gye-Won Han, Lijie Wu, Junlin Liu, Bo Chen, Zhibin Zhang, Suwen Zhao, Vadim Cherezov, Fei Xu