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Mucosal administration of a live attenuated recombinant COVID-19 vaccine protects nonhuman primates from SARS-CoV-2
Authors: Mariana F Tioni, Robert Jordan, Angie Silva Pena, Aditya Garg, Danlu Wu, Shannon I Phan, Christopher M Weiss, Xing Cheng, Jack Greenhouse, Tatyana Orekov, Daniel Valentin, Swagata Kar, Laurent Pessaint, Hanne Andersen, Christopher C Stobart, Melissa H Bloodworth, R Stokes Peebles, Yang Liu, Xuping Xie, Pei-Yong Shi, Martin L Moore, Roderick S Tang
Journal: npj Vaccines
PubMed ID: 35906244
Doi: 10.1038/s41541-022-00509-6
Products & Services: Proteins, Expression, Isolation and Analysis   
Polymeric nanoparticles for dual-targeted theranostic gene delivery to hepatocellular carcinoma
Authors: Hannah J Vaughan, Camila G Zamboni, Laboni F Hassan, Nicholas P Radant, Desmond Jacob, Ronnie C Mease, Il Minn, Stephany Y Tzeng, Kathleen L Gabrielson, Pranshu Bhardwaj, Xin Guo, David Francisco, Martin G Pomper, Jordan J Green
Journal: Sci Adv
PubMed ID: 35857843
Doi: 10.1126/sciadv.abo6406
Products & Services: Gene Synthesis   
Self-Masked Aldehyde Inhibitors of Human Cathepsin L Are Potent Anti-CoV-2 Agents
Authors: Jiyun Zhu, Linfeng Li, Aleksandra Drelich, Bala C Chenna, Drake M Mellott, Zane W Taylor, Vivian Tat, Christopher Z Garcia, Ardala Katzfuss, Chien-Te K Tseng, Thomas D Meek
Journal: Front Chem
PubMed ID: 35860632
Doi: 10.3389/fchem.2022.867928
Products & Services: Gene Synthesis   
HJM-561, a Potent, Selective, and Orally Bioavailable EGFR PROTAC that Overcomes Osimertinib-Resistant EGFR Triple Mutations
Authors: Yong Du, Yongfeng Chen, Yuxia Wang, Jinju Chen, Xiaorong Lu, Li Zhang, Yan Li, Zhaofu Wang, Guozhong Ye, George Zhang
Journal: Mol Cancer Ther
PubMed ID: 35499406
Doi: 10.1158/1535-7163.MCT-21-0835
Products & Services: Proteins, Expression, Isolation and Analysis   
Ligand-induced transmembrane conformational coupling in monomeric EGFR
Authors: Shwetha Srinivasan, Raju Regmi, Xingcheng Lin, Courtney A Dreyer, Xuyan Chen, Steven D Quinn, Wei He, Matthew A Coleman, Kermit L Carraway, Bin Zhang, Gabriela S Schlau-Cohen
Journal: Nat Commun
PubMed ID: 35794108
Doi: 10.1038/s41467-022-31299-z
Products & Services: Mutagenesis Services   
Erythroid lineage Jak2V617F expression promotes atherosclerosis through erythrophagocytosis and macrophage ferroptosis
Authors: Wenli Liu, Nataliya Östberg, Mustafa Yalcinkaya, Huijuan Dou, Kaori Endo-Umeda, Yang Tang, Xintong Hou, Tong Xiao, Trevor P Fidler, Sandra Abramowicz, Yong-Guang Yang, Oliver Soehnlein, Alan R Tall, Nan Wang
Journal: J Clin Invest
PubMed ID: 35587375
Doi: 10.1172/JCI155724
Products & Services: Recombinant Proteins   
Construction of a Novel Clinical Stage-Related Gene Signature for Predicting Outcome and Immune Response in Hepatocellular Carcinoma
Authors: Liu Yang, Long-Fei Zeng, Guo-Qing Hong, Qing Luo, Xing Lai
Journal: J Immunol Res
PubMed ID: 35865652
Doi: 10.1155/2022/6535009
Products & Services: Custom DNA/RNA Oligos   
Apela gene therapy alleviates pulmonary hypertension in rats
Authors: Yuexin Hu, Liangli Jin, Yang Pan, Jue Zou, Zhi Wang
Journal: FASEB J
PubMed ID: 35747913
Doi: 10.1096/fj.202200266R
Products & Services: Plasmid DNA Preparation   
Cryo-EM structure of the human Kv3.1 channel reveals gating control by the cytoplasmic T1 domain
Authors: Gamma Chi , Qiansheng Liang , Akshay Sridhar , John B Cowgill , Kasim Sader , Mazdak Radjainia , Pu Qian , Pablo Castro-Hartmann , Shayla Venkaya , Nanki Kaur Singh , Gavin McKinley , Alejandra Fernandez-Cid , Shubhashish M M Mukhopadhyay , Nicola A Burgess-Brown , Lucie Delemotte , Manuel Covarrubias , Katharina L Dürr
Journal: Nat Commun
PubMed ID: 35840580
Doi: 10.1038/s41467-022-29594-w
Products & Services: Plasmid DNA Preparation   
Induction of Broadly Cross-Reactive Antibody Responses to SARS-CoV-2 Variants by S1 Nanoparticle Vaccines
Authors: Cong Sun , Run-Yu Yuan , Chu Xie , Jiu-Feng Sun , Xin-Yan Fang , Yi-Sha Hu , Xiao-Hui Yu, Zheng Liu , Mu-Sheng Zeng , Yin-Feng Kang
Journal: J Virol
PubMed ID: 35699445
Doi: 10.1128/jvi.00383-22
Products & Services: Gene Synthesis   Endotoxin Detection & Removal System   

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