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Generation of hepatoma cell lines deficient in microsomal triglyceride transfer protein
Authors: Narasimha Anaganti, Atrayee Chattopadhyay, John T Poirier, M Mahmood Hussain
Journal: J Lipid Res
PubMed ID: 35931202
Doi: 10.1016/j.jlr.2022.100257
Products & Services: Catalog Peptides   
Tumor-infiltrated activated B cells suppress liver metastasis of colorectal cancers
Authors: Yuqiu Xu, Zhuang Wei, Mei Feng, Dexiang Zhu, Shenglin Mei, Zhongen Wu, Qingyang Feng, Wenju Chang, Meiling Ji, Chenglong Liu, Yuanyuan Zhu, Lian Shen, Fan Yang, Yijiao Chen, Yuxiong Feng, Jianmin Xu, Di Zhu
Journal: Cell Rep
PubMed ID: 36044847
Doi: 10.1016/j.celrep.2022.111295
Products & Services: Recombinant Proteins   
Biophysical and pharmacokinetic characterization of a small-molecule inhibitor of RUNX1/ETO tetramerization with anti-leukemic effects
Authors: Mohanraj Gopalswamy, Tobias Kroeger, David Bickel, Benedikt Frieg, Shahina Akter, Stephan Schott-Verdugo, Aldino Viegas, Thomas Pauly, Manuela Mayer, Julia Przibilla, Jens Reiners, Luitgard Nagel-Steger, Sander H J Smits, Georg Groth, Manuel Etzkorn, Holger Gohlke
Journal: Sci Rep
PubMed ID: 35986043
Doi: 10.1038/s41598-022-17913-6
Products & Services: Proteins, Expression, Isolation and Analysis   
Evolutionary adaptation of the protein folding pathway for secretability
Authors: Dries Smets, Alexandra Tsirigotaki, Jochem H Smit, Srinath Krishnamurthy, Athina G Portaliou, Anastassia Vorobieva, Wim Vranken, Spyridoula Karamanou, Anastassios Economou
Journal: EMBO J
PubMed ID: 36031863
Doi: 10.15252/embj.2022111344
Products & Services: Custom Vector Construction   
Dipeptidyl peptidase 9 triggers BRCA2 degradationand promotes DNA damage repair
Authors: Oguz Bolgi 1 2, Maria Silva-Garcia 2, Breyan Ross 3 4, Esther Pilla 2, Vijayalakshmi Kari 5, Markus Killisch 2, Melanie Spitzner 5, Nadine Stark 6, Christof Lenz 7 8, Konstantin Weiss 9, Laura Donzelli 1, Mark D Gorrell 10, Marian Grade 5, Jan Riemer 9, Henning Urlaub 7 8, Matthias Dobbelstein 6, Robert Huber 3 11 12, Ruth Geiss-Friedlander 1 2
Journal: EMBO Rep
PubMed ID: 35912982
Doi: 10.15252/embr.202154136
Products & Services: Peptide Synthesis   
Regulation of Host Immune Response against Proteins via Computational mRNA Vaccine Design through Transcriptional Modification
Authors: Muhammad Naveed, Khizra Jabeen, Rubina Naz, Muhammad Saad Mughal, Ali A Rabaan, Muhammed A Bakhrebah, Fahad M Alhoshani, Mohammed Aljeldah, Basim R Al Shammari, Mohammed Alissa, Amal A Sabour, Rana A Alaeq, Maha A Alshiekheid, Mohammed Garout, Mohammed S Almogbel, Muhammad A Halwani, Safaa A Turkistani, Naveed Ahmed
Journal: Microorganisms
PubMed ID: 36014038
Doi: 10.3390/microorganisms10081621
Products & Services: Molecular Biology Tools   
Ancestral Sequence Reconstruction Identifies Structural Changes Underlying the Evolution of PETase and Variants with Improved Stability and Activity
Authors: Yvonne Joho, Vanessa Vongsouthi, Matthew A Spence, Jennifer Ton, Chloe Gomez, Li Lynn Tan, Joe A Kaczmarski, Alessandro T Caputo, Santana Royan, Colin J Jackson, Albert Ardevol
Journal: Biochemistry
PubMed ID: 35951410
Doi: 10.1021/acs.biochem.2c00323
Products & Services: Proteins, Expression, Isolation and Analysis   
Individualized, heterologous chimpanzee adenovirus and self-amplifying mRNA neoantigen vaccine for advanced metastatic solid tumors: phase 1 trial interim results
Authors: Christine D Palmer, Amy R Rappaport, Matthew J Davis, Meghan G Hart, Ciaran D Scallan, Sue-Jean Hong, Leonid Gitlin, Lauren D Kraemer, Sonia Kounlavouth, Aaron Yang, Lindsey Smith, Desiree Schenk, Mojca Skoberne, Kiara Taquechel, Martina Marrali, Jason R Jaroslavsky, Charmaine N Nganje, Elizabeth Maloney, Rita Zhou, Daniel Navarro-Gomez, Adrienne C Greene, Gijsbert Grotenbreg, Renee Greer, Wade Blair, Minh Duc Cao, Shawn Chan, Kyounghwa Bae, Alexander I Spira, Sameek Roychowdhury, David P Carbone, Brian S Henick, Charles G Drake, Benjamin J Solomon, Daniel H Ahn, Amit Mahipal, Steve B Maron, Benny Johnson, Raphael Rousseau, Roman Yelensky, Chih-Yi Liao, Daniel V T Catenacci, Andrew Allen, Andrew R Ferguson, Karin Jooss
Journal: Nat Med
PubMed ID: 35970920
Doi: 10.1038/s41591-022-01937-6
Products & Services: Plasmid DNA Preparation   
Rabbit hemorrhagic disease virus VP60 protein expressed in recombinant swinepox virus self-assembles into virus-like particles with strong immunogenicity in rabbits
Authors: Changjin Liu, Min Lin, Huanyi Hu, Xiaolan Liu, Yanchao Bian, Xiaohua Huang, Xiaoxiang Li, Wenyang Yu, Feng Luo, Shunzhou Deng
Journal: Front Microbiol
PubMed ID: 35992711
Doi: 10.3389/fmicb.2022.960374
Products & Services: Plasmid DNA Preparation   
Investigation of Transcript Variant 6 of as a Prognostic and Predictive Biomarker in Basal-Like MDA-MB-231 and MDA-MB-453 Cell Lines for Breast Cancer
Authors: Xin Zhang, Daniel O'Brien, Xiaohui Zhang
Journal: Oxid Med Cell Longev
PubMed ID: 36071863
Doi: 10.1155/2022/7078787
Products & Services: Plasmid DNA Preparation   

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