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Crosstalk between regulatory elements in disordered TRPV4 N-terminus modulates lipid-dependent channel activity

Authors: Benedikt Goretzki, Christoph Wiedemann, Brett A McCray, Stefan L Schäfer, Jasmin Jansen, Frederike Tebbe, Sarah-Ana Mitrovic, Julia Nöth, Ainara Claveras Cabezudo, Jack K Donohue, Cy M Jeffries, Wieland Steinchen, Florian Stengel, Charlotte J Sumner, Gerhard Hummer, Ute A Hellmich

Journal: Nat Commun

PubMed ID: 37443299

Doi: 10.1038/s41467-023-39808-4

Products & Services: Plasmid DNA Preparation

Absolute Quantification of Photoreceptor Outer Segment Proteins

Authors: Nikolai P Skiba, Tylor R Lewis, William J Spencer, Carson M Castillo, Andrej Shevchenko, Vadim Y Arshavsky

Journal: J Proteome Res

PubMed ID: 37493966

Doi: 10.1021/acs.jproteome.3c00267

Products & Services: Peptide Synthesis

Computationally Designed Small Molecules Disassemble Both Soluble Oligomers and Protofibrils of Amyloid β-Protein Responsible for Alzheimer's Disease

Authors: Yingying Jin, Matthew A Downey, Ambuj Singh, Steven K Buratto, Michael T Bowers

Journal: ACS Chem Neurosci

PubMed ID: 37442126

Doi: 10.1021/acschemneuro.3c00266

Products & Services: Protein and Antibody Isolation

Mesothelin-targeting T cell receptor fusion construct cell therapy in refractory solid tumors: phase 1/2 trial interim results

Authors: Raffit Hassan, Marcus Butler, Roisin E O'Cearbhaill, David Y Oh, Melissa Johnson, Kevin Zikaras, Munisha Smalley, Michael Ross, Janos L Tanyi, Azam Ghafoor, Nirali N Shah, Babak Saboury, Liang Cao, Alfonso Quintás-Cardama, David Hong

Journal: Nat Med

PubMed ID: 37501016

Doi: 10.1038/s41591-023-02452-y

Products & Services: Protein and Antibody Isolation

Combined Inhibition of the TGF-β1/Smad Pathway by and to Reduce Inflammation and Fibrosis in Primary Sclerosing Cholangitis

Authors: Yu Shen, Baorong Jiang, Chenchen Zhang, Qian Wu, Lei Li, Ping Jiang

Journal: Int J Mol Sci

PubMed ID: 37446187

Doi: 10.3390/ijms241311010

Products & Services: Protein and Antibody Isolation

Perdeuterated GbpA Enables Neutron Scattering Experiments of a Lytic Polysaccharide Monooxygenase

Authors: H V Sørensen, Mateu Montserrat-Canals, Jennifer S M Loose, S Zoë Fisher, Martine Moulin, Matthew P Blakeley, Gabriele Cordara, Kaare Bjerregaard-Andersen, Ute Krengel

Journal: ACS Omega

PubMed ID: 37599915

Doi: 10.1021/acsomega.3c02168

Products & Services: Protein and Antibody Isolation

Viral manipulation of cell polarity signalling

Authors: Airah Javorsky, Patrick O Humbert, Marc Kvansakul

Journal: Biochim Biophys Acta Mol Cell Res

PubMed ID: 37437846

Doi: 10.1016/j.bbamcr.2023.119536

Products & Services: Molecular Biology Reagents

Immunogenicity and safety of inactivated SARS-CoV-2 vaccine in haemodialysis patients: a prospective cohort study

Authors: Metalia Puspitasari, Prenali D Sattwika, Dzerlina S Rahari, Wynne Wijaya, Auliana R P Hidayat, Nyoman Kertia, Bambang Purwanto, Jarir At Thobari

Journal: Sci Rep

PubMed ID: 37463975

Doi: 10.1038/s41598-023-38628-2

Products & Services: Molecular Biology Reagents

The combination of osimertinib with Raf inhibitor overcomes osimertinib resistance induced by KRAS amplification in EGFR-mutated lung cancer cells

Authors: Tae-Gul Lee, Hye-Min Kang, Seo Yun Kim, Hye-Ryoun Kim, Cheol Hyeon Kim

Journal: Exp Cell Res

PubMed ID: 37442265

Doi: 10.1016/j.yexcr.2023.113722

Products & Services: Protein and Antibody Isolation

Targeting CXCR4-expressing Cancer Cells with Avidin-poly (lactic-co-glycolic acid) Nanoparticle Surface Modified with Biotinylated DV1 Peptide

Authors: Shiba Ansari, Madeeha Mudassir, B Vijayalekshmi, Parthaprasad Chattopadhyay

Journal: Int J Appl Basic Med Res

PubMed ID: 37614837

Doi: 10.4103/ijabmr.ijabmr_58_23

Products & Services: Peptide Synthesis