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Glc7/PP1 dephosphorylates histone H3T11 to regulate autophagy and telomere silencing in response to nutrient availability

Authors: Xinyu Zhang, Qi Yu, Yinsheng Wu, Yuan Zhang, Yi He, Rongsha Wang, Xilan Yu,Shanshan Li

Journal: Cell Discovery

Doi: 10.1038/s41421-023-00551-1

Products & Services: Antibody Modification and Purification Services

A new compact adenine base editor generated through deletion of HNH and REC2 domain of SpCas9

Authors: Yuqiang Qian , Di Wang , Wenchao Niu , Ding Zhao , Jinze Li , Zhiquan Liu , Xun Gao , Yang Han , Liangxue Lai , Zhanjun Li

Journal: BMC Biol .

PubMed ID: 37434184

Doi: 10.1186/s12915-023-01644-9

Products & Services: Synthetic Guide RNA

Chemo-enzymatic cascades producing 2,5- furandicarboxylic acid precursors via D-gluconate “barbell oxidation” and dehydration

Authors: Jiao Chen, a,b Jiali Cai,c Feng Sha,d Wenjun Sun,a Xilei Lyu,e Yonghui Chang,f Fei Cao, Lili Zhao, Hongli Wu and Pingkai Ouyang

Journal: Green Chem.

Doi: 10.1039/d3gc01493b

Products & Services: Gene Synthesis

Broad protection against clade 1 sarbecoviruses after a single immunization with cocktail spike-protein-nanoparticle vaccine

Authors: Peter J. Halfmann; Kathryn Loeffler; Augustine Duffy; Makoto Kuroda; Jie E. Yang; Elizabeth R. Wright; Yoshihiro Kawaoka; Ravi S. Kane

Journal: Nature Communications

PubMed ID: 38346966

Doi: 10.1038/s41467-024-45495-6

Products & Services: PCR Cloning and Subcloning

Broad protection against clade 1 sarbecoviruses after a single immunization with cocktail spike-protein-nanoparticle vaccine

Authors: Peter J. Halfmann; Kathryn Loeffler; Augustine Duffy; Makoto Kuroda; Jie E. Yang; Elizabeth R. Wright; Yoshihiro Kawaoka; Ravi S. Kane

Journal: Nature Communications

PubMed ID: 38346966

Doi: 10.1038/s41467-024-45495-6

Products & Services: PCR Cloning and Subcloning

Development of chimeric protein as a multivalent vaccine for human Kinetoplastid infections: Chagas disease and leishmaniasis

Authors: Marianna de Carvalho Clímaco, Luiza Almeida de Figueiredo, Rayane Cristina Lucas, Guilherme Rafael Gomide Pinheiro, Luísa Mourão Dias Magalhães, Ana Laura Grossi de Oliveira, Raquel Martins Almeida, Fernando Sérgio Barbosa, Daniella Castanheira Bartholomeu, Lilian Lacerda Bueno, Tiago Antonio Mendes, Bin Zhan, Kathryn Marie Jones, Peter Hotez, Maria Elena Bottazzi, Fabrício Marcus Silva Oliveira, Ricardo Toshio Fujiwara

Journal: Vaccine

PubMed ID: 37479612

Doi: 10.1016/j.vaccine.2023.07.020

Products & Services: Gene Synthesis

Integrated analysis and validation of TRIM23/p53 signaling pathway in hepatic stellate cells ferroptosis and liver fibrosis

Authors: Jie Chen, Rui Zhang, Feng Li, Shengli Lin, Jian Wang

Journal: Dig Liver Dis

PubMed ID: 37495427

Doi: 10.1016/j.dld.2023.07.010

Products & Services: Molecular Biology Reagents

Structure-based design of SARS-CoV-2 papain-like protease inhibitors

Authors: Prakash Jadhav; Bo Huang; Jerzy Osipiuk; Xiaoming Zhang; Haozhou Tan; Christine Tesar; Michael Endres; Robert Jedrzejczak; Bin Tan; Xufang Deng; Andrzej Joachimiak; Jianfeng Cai; Jun Wang

Journal: European Journal of Medicinal Chemistry

PubMed ID: 38065031

Doi: 10.1016/j.ejmech.2023.116011

Structure-based design of SARS-CoV-2 papain-like protease inhibitors

Authors: Prakash Jadhav; Bo Huang; Jerzy Osipiuk; Xiaoming Zhang; Haozhou Tan; Christine Tesar; Michael Endres; Robert Jedrzejczak; Bin Tan; Xufang Deng; Andrzej Joachimiak; Jianfeng Cai; Jun Wang

Journal: European Journal of Medicinal Chemistry

PubMed ID: 38065031

Doi: 10.1016/j.ejmech.2023.116011

Tepsin binds LC3B to promote ATG9A export and delivery at the cell periphery

Authors: Natalie S Wallace, John E Gadbery, Cameron I Cohen, Amy K Kendall, Lauren P Jackson

Journal: biorxiv

PubMed ID: 37502979

Doi: 10.1101/2023.07.18.549521

Products & Services: Protein and Antibody Isolation