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Maximizing Heterologous Expression of Engineered Type I Polyketide Synthases: Investigating Codon Optimization Strategies

Authors: Matthias Schmidt, Namil Lee, Chunjun Zhan, Jacob B Roberts, Alberto A Nava, Leah S Keiser, Aaron A Vilchez, Yan Chen, Christopher J Petzold, Robert W Haushalter, Lars M Blank, Jay D Keasling

Journal: ACS Synth Biol

PubMed ID: 37851920

Doi: 10.1021/acssynbio.3c00367

Products & Services: Protein and Antibody Isolation

CRISPR/Cas9 System-Mediated Multi-copy Expression of an Alkaline Serine Protease in for the Production of XOD-Inhibitory Peptides

Authors: Shounan Wang, Yibin Xue, Peng Zhang, Qiaojuan Yan, Yanxiao Li, Zhengqiang Jiang

Journal: J Agric Food Chem

PubMed ID: 37807677

Doi: 10.1021/acs.jafc.3c04138

Products & Services: Protein and Antibody Isolation

Regulatory T cell-like response to SARS-CoV-2 in Jamaican fruit bats (Artibeus jamaicensis) transduced with human ACE2

Authors: Bradly Burke, Savannah M Rocha, Shijun Zhan, Miles Eckley, Clara Reasoner, Amin Addetia, Juliette Lewis, Anna Fagre, Phillida A Charley, Juergen A Richt, Susan R Weiss, Ronald B Tjalkens, David Veesler, Tawfik Aboellail, Tony Schountz

Journal: PLoS Pathog

PubMed ID: 37856551

Doi: 10.1371/journal.ppat.1011728

Products & Services: Protein and Antibody Isolation

Fasciola hepatica antioxidant and protease-inhibitor cocktail recombinant vaccines administered five times elicit potent and sustained immune responses in sheep but do not confer protection

Authors: Krystyna Cwiklinski, Amanda McEvoy, Jesús López Corrales, Heather Jewhurst, Nichola Eliza Davies Calvani, Carolina De Marco Verissimo, Amber Louise Dorey, Orla M Keane, John Pius Dalton, Richard Lalor

Journal: Vet Parasitol

PubMed ID: 37826973

Doi: 10.1016/j.vetpar.2023.110049

Products & Services: Protein and Antibody Isolation

UV-induced G4 DNA structures recruit ZRF1 which prevents UV-induced senescence

Authors: Alessio De Magis, Michaela Limmer, Venkat Mudiyam, David Monchaud, Stefan Juranek, Katrin Paeschke

Journal: Nat Commun

PubMed ID: 37872164

Doi: 10.1038/s41467-023-42494-x

Products & Services: Protein and Antibody Isolation

Adapting antibacterial display to identify serum active macrocyclic peptide antibiotics

Authors: Justin R. Randall; Kyra E. Groover; Angela C. O Donnell; Joseph M. Garza; T. Jeffrey Cole; Bryan W. Davies

Journal: biorxiv

PubMed ID: 37546850

Doi: 10.1101/2023.07.28.550711

Products & Services: Peptide Synthesis

Application of luminescence-producing Mycobacterium tuberculosis strains for evaluating anti-tuberculosis drug and vaccine efficacy in vitro and in vivo

Authors: Soo-Min Kim; Eunkyung Shin; Jin-Seung Yun; Jaeseon Jeon; Sohee Park; Yong Woo Jung; Dokeun Kim; Hye-Sook Jeong

Journal: BMC infectious diseases

PubMed ID: 41965567

Doi: 10.1186/s12879-026-13140-w

Molecular mechanism of decision-making in glycosaminoglycan biosynthesis

Authors: Douglas Sammon, Anja Krueger, Marta Busse-Wicher, Rhodri Marc Morgan, Stuart M Haslam, Benjamin Schumann, David C Briggs, Erhard Hohenester

Journal: Nat Commun

PubMed ID: 37828045

Doi: 10.1038/s41467-023-42236-z

Products & Services: Peptide Synthesis

A morpheein equilibrium regulates catalysis in phosphoserine phosphatase SerB2 from Mycobacterium tuberculosis

Authors: Elise Pierson, Florian De Pol, Marianne Fillet, Johan Wouters

Journal: Commun Biol

PubMed ID: 37817000

Doi: 10.1038/s42003-023-05402-z

Products & Services: CRISPR Plasmids

Aggregative adherence fimbriae form compact structures as seen by SAXS

Authors: Rie Jønsson, Alexander Björling, Søren Roi Midtgaard, Grethe Vestergaard Jensen, Nicholas Skar-Gislinge, Lise Arleth, Steve Matthews, Karen Angeliki Krogfelt, Håvard Jenssen

Journal: Sci Rep

PubMed ID: 37783694

Doi: 10.1038/s41598-023-42079-0

Products & Services: Protein and Antibody Isolation