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Highly potent inhibitors of cathepsin K with a differently positioned cyanohydrazide warhead: structural analysis of binding mode to mature and zymogen-like enzymes
Authors: Jakub Benýšek, Michal Buša, Petra Rubešová, Jindřich Fanfrlík, Martin Lepšík, Jiří Brynda, Zuzana Matoušková, Ulrike Bartz, Martin Horn, Michael Gütschow, Michael Mareš
Journal: J Enzyme Inhib Med Chem
PubMed ID: 35144520
Doi: 10.1080/14756366.2021.2024527
Products & Services: Plasmid DNA Preparation   
A De Novo Missense Variant in TUBG2 in a Child with Global Developmental Delay, Microcephaly, Refractory Epilepsy and Perisylvian Polymicrogyria
Authors: Salini Thulasirajah, Xueqi Wang, Erick Sell, Jorge Dávila, David A Dyment, Kristin D Kernohan
Journal: Genes
PubMed ID: 36672848
Doi: 10.3390/genes14010108
Products & Services: Mutagenesis Services   
Inhibition of autophagy reduces the rate of fluoride-induced LS8 apoptosis via regulating ATG5 and ATG7
Authors: Lin Zhao, Han Wang, Sijia Liu, Tao Xi, Liyuan Wang, Yang Li, Lu Chen, Ruan Jianping, Kristina Xiao Liang
Journal: J Biochem Mol Toxicol
PubMed ID: 36536498
Doi: 10.1002/jbt.23280
Products & Services: Gene Synthesis   
Cryo-EM Structure of the Type IV Pilus Extension ATPase from Enteropathogenic Escherichia coli
Authors: Ashok R Nayak , Pradip K Singh , Jinlei Zhao , Montserrat Samsó , Michael S Donnenberg
Journal: mBio
PubMed ID: 36326250
Doi: 10.1128/mbio.02270-22
Products & Services: Molecular Biology Reagents   
Mesenchymal stem cell-originated exosomal circDIDO1 suppresses hepatic stellate cell activation by miR-141-3p/PTEN/AKT pathway in human liver fibrosis
Authors: Li Ma, Junfeng Wei, Yanli Zeng, Junping Liu, Erhui Xiao, Yuehua Kang, Yi Kang
Journal: Drug Deliv
PubMed ID: 35099348
Doi: 10.1080/10717544.2022.2030428
Products & Services: Proteins, Expression, Isolation and Analysis   
Suchilactone inhibits the growth of acute myeloid leukaemia by inactivating SHP2
Authors: Jingjing Wu, Yuan Deng, Xin Zhang, Jingjing Ma, Xinqi Zheng, Yue Chen
Journal: Pharm Biol
PubMed ID: 34962431
Doi: 10.1080/13880209.2021.2017467
Products & Services: Custom DNA/RNA Oligos   
ADAR1 improved Treg cell function through the miR-21b/Foxp3 axis and inhibits the progression of acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation
Authors: Yanru Zhao, Xiaoyan Zheng, Miaojing Li, Jing Zhao, Xiaoning Wang, Huachao Zhu
Journal: Int Immunopharmacol
PubMed ID: 36577155
Doi: 10.1016/j.intimp.2022.109620
Products & Services: Gene Synthesis   
GmYSL7 controls iron uptake, allocation, and cellular response of nodules in soybean
Authors: Xinying Wu, Yongliang Wang, Qiaohan Ni, Haizhen Li, Xuesong Wu, Zhanxin Yuan, Renhao Xiao, Ziyin Ren, Jingjing Lu, Jinxia Yun, Zhijuan Wang, Xia Li
Journal: J Integr Plant Biol
PubMed ID: 36107150
Doi: 10.1111/jipb.13364
Products & Services: Proteins, Expression, Isolation and Analysis   
DeGlyPHER: Highly sensitive site-specific analysis of N-linked glycans on proteins
Authors: Sabyasachi Baboo, Jolene K Diedrich, Salvador Martínez-Bartolomé, Xiaoning Wang, Torben Schiffner, Bettina Groschel, William R Schief, James C Paulson, John R Yates
Journal: Methods Enzymol
PubMed ID: 36948700
Doi: 10.1016/bs.mie.2022.09.004
Products & Services: Proteins, Expression, Isolation and Analysis   
Imprinted SARS-CoV-2 humoral immunity induces convergent Omicron RBD evolution
Authors: Yunlong Cao, Fanchong Jian, Jing Wang, Yuanling Yu, Weiliang Song, Ayijiang Yisimayi, Jing Wang, Ran An, Xiaosu Chen, Na Zhang, Yao Wang, Peng Wang, Lijuan Zhao, Haiyan Sun, Lingling Yu, Sijie Yang, Xiao Niu, Tianhe Xiao, Qingqing Gu, Fei Shao, Xiaohua Hao, Yanli Xu, Ronghua Jin, Zhongyang Shen, Youchun Wang, Xiaoliang Sunney Xie
Journal: Nature
PubMed ID: 36535326
Doi: 10.1038/s41586-022-05644-7
Products & Services: Proteins, Expression, Isolation and Analysis   

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