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Cancer Relevance of Circulating Antibodies Against LINE-1 Antigens in Humans

Authors: Alexandra V Vylegzhanina, Ivan A Bespalov, Ksenia A Novototskaya-Vlasova, Brandon M Hall, Anatoli S Gleiberman, Han Yu, Olga V Leontieva, Katerina I Leonova, Oleg V Kurnasov, Andrei L Osterman, Grace K Dy, Alexey A Komissarov, Elena Vasilieva, Jeff Gehlhausen, Akiko Iwasaki, Christine B Ambrosone, Takemasa Tsuji, Junko Matsuzaki, Kunle Odunsi, Ekaterina L Andrianova, Andrei V Gudkov

Journal: Cancer Res Commun

PubMed ID: 37870410

Doi: 10.1158/2767-9764.CRC-23-0289

Products & Services: Protein and Antibody Isolation

Allosteric coupling of substrate binding and proton translocation in MmpL3 transporter from Mycobacterium tuberculosis

Authors: Svitlana Babii; Wei Li; Lixinhao Yang; Anna E. Grzegorzewicz; Mary Jackson; James C. Gumbart; Helen I. Zgurskaya

Journal: MBio

PubMed ID: 39212407

Doi: 10.1128/mbio.02183-24

Products & Services: Mutagenesis Services

NINJ1 is activated by cell swelling to regulate plasma membrane permeabilization during regulated necrosis

Authors: Yves Dondelinger, Dario Priem, Jon Huyghe, Tom Delanghe, Peter Vandenabeele, Mathieu J M Bertrand

Journal: Cell Death Dis

PubMed ID: 37980412

Doi: 10.1038/s41419-023-06284-z

Products & Services: Molecular Biology Reagents

Mesenchymal stem cells attenuate systemic lupus erythematosus by inhibiting NLRP3 inflammasome activation through Pim-1 kinase

Authors: Honghong Yu, Qi Li, Huimin Zhu, Chang Liu, Weiwei Chen, Lingyun Sun

Journal: Int Immunopharmacol

PubMed ID: 37992447

Doi: 10.1016/j.intimp.2023.111256

Products & Services: Gene Synthesis

Human leukocyte antigen HLA-DR-expressing fibroblast-like synoviocytes are inducible antigen presenting cells that present autoantigens in Lyme arthritis

Authors: Joseph R Rouse, Rebecca Danner, Amanda Wahhab, Michaela Pereckas, Mecaila E McClune, Allen C Steere, Klemen Strle, Brandon L Jutras, Robert B Lochhead

Journal: biorxiv

PubMed ID: 38045407

Doi: 10.1101/2023.11.21.568066

Products & Services: Peptide Synthesis

BRD4354 is a Potent Covalent Inhibitor against the SARS-CoV-2 Main Protease

Authors: Yan J. Sheng; Syuan-Ting Alex Kuo; Tingyuan Yang; David H. Russell; Xin Yan; Shiqing Xu; Wenshe R. Liu; Carol A. Fierke

Journal: Biochemistry

PubMed ID: 38329238

Doi: 10.1021/acs.biochem.3c00685

Products & Services: Protein and Antibody Isolation

Rational immunosilencing of a promiscuous T-cell epitope in the capsid of an adeno-associated virus

Authors: So Jin Bing, Morten Seirup, Trish T Hoang, Susana S Najera, Collin Britten, Stephanee L Warrington, Shiang-Ling Chu, Ronit Mazor

Journal: Nat Biomed Eng

PubMed ID: 37996615

Doi: 10.1038/s41551-023-01129-8

Products & Services: Peptide Synthesis

DNAJB6 mutants display toxic gain of function through unregulated interaction with Hsp70 chaperones

Authors: Meital Abayev-Avraham, Yehuda Salzberg, Dar Gliksberg, Meital Oren-Suissa, Rina Rosenzweig

Journal: Nat Commun

PubMed ID: 37923706

Doi: 10.1038/s41467-023-42735-z

Products & Services: Protein and Antibody Isolation

Critical role of TPRN rings in the stereocilia for hearing

Authors: Jieyu Qi, Fangzhi Tan, Liyan Zhang, Yinyi Zhou, Ziyu Zhang, Qiuhan Sun, Nianci Li, Yuan Fang, Xin Chen, Yunhao Wu, Guisheng Zhong, Renjie Chai

Journal: Mol Ther

PubMed ID: 37952086

Doi: 10.1016/j.ymthe.2023.11.011

Products & Services: Protein and Antibody Isolation

Interactions of Histone Deacetylase 6 with DNA Damage Repair Factors Strengthen its Utility as a Combination Drug Target in High-Grade Serous Ovarian Cancer

Authors: Jolene M Duda, Stefani N Thomas

Journal: ACS Pharmacol Transl Sci

PubMed ID: 38107255

Doi: 10.1021/acsptsci.3c00215

Products & Services: Protein and Antibody Isolation