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MARS an improved de novo peptide candidate selection method for non-canonical antigen target discovery in cancer

Authors: Hanqing Liao , Carolina Barra , Zhicheng Zhou , Xu Peng , Isaac Woodhouse , Arun Tailor , Robert Parker , Alexia Carré , Persephone Borrow , Michael J Hogan , Wayne Paes , Laurence C Eisenlohr , Roberto Mallone , Morten Nielsen , Nicola Ternette

Journal: Nat Commun

PubMed ID: 38253617

Doi: 10.1038/s41467-023-44460-z

Products & Services: Peptide Synthesis

Role of UPF1-LIN28A interaction during early differentiation of pluripotent stem cells

Authors: Seungwon Jung , Seung Hwan Ko , Narae Ahn , Jinsam Lee , Chang-Hwan Park , Jungwook Hwang

Journal: Nat Commun

PubMed ID: 38167913

Doi: 10.1038/s41467-023-44600-5

Products & Services: Polyclonal Antibody Services

The role of CD38 in inflammation-induced depression-like behavior and the antidepressant effect of (R)-ketamine

Authors: Xinying Zhang a , Teng He a , Zifeng Wu a , Yuanyuan Wang a, Hanyu Liu a, Bingyuan Zhang a, Siqi Yang a, Di Wang a, Chaoli Huang a, Jiahao Duan b, Xiangyang Xu c, Xiangqing Xu c, Kenji Hashimoto d, Riyue Jiang e, Ling Yang b, Chun Yang

Journal: Brain, behavior, and immunity

PubMed ID: 37793489

Doi: 10.1016/j.bbi.2023.09.026

Products & Services: Gene Synthesis

The role of the Toll like receptor 4 signaling in sex-specific persistency of depression-like behavior in response to chronic stress

Authors: Eun-Jeong Yang , Tal Frolinger , Umar Iqbal , Molly Estill , Li Shen , Kyle J Trageser , Giulio M Pasinetti

Journal: Brain, behavior, and immunity

PubMed ID: 37838079

Doi: 10.1016/j.bbi.2023.10.006

Products & Services: Gene Synthesis

Acylspermidines are conserved mitochondrial sirtuin-dependent metabolites

Authors: Bingsen Zhang, James Mullmann, Andreas H. Ludewig, Irma R. Fernandez, Tyler R. Bales, Robert S. Weiss & Frank C. Schroeder

Journal: Nature Chemical Biology

PubMed ID: 38167917

Doi: 10.1038/s41589-023-01511-2

Products & Services: Antibody Modification and Purification Services

Expanding the toolbox to develop IAP-based degraders of TEAD transcription factors

Authors: Nishma Gupta; Nicole Trainor; Mona Radwan; Stephanie Nguyen; Luke Duncan; Andrew X. Tang; Julia Beveridge; Natasha Silke; Jumana Yousef; Ceren Bilgilier; Johannes Wachter; Peter Greb; Zuzana Jandova; J n Elia ; Sara Kopf; Thomas Gerstberger; Peggy Stolt-Bergner; Nina Braun; Harald Weinstabl; Darryl B. McConnell; Federico Mauri; Isabelle S. Lucet; John Silke; Nicola E. A. Chessum; Michael J. Roy

Journal: Communications Chemistry

PubMed ID: 41554911

Doi: 10.1038/s42004-025-01871-x

Extracellular vesicle-mediated gene editing for the treatment of non-syndromic progressive hearing loss in adult mice

Authors: Xiaoshu Pan; Peixin Huang; Samantha S. Ali; Bryan Renslo; Zachary Greenberg; Nina Erwin; Yanjun Li; Zuo Ding; Tarun E Hutchinson; Athanasia Warnecke; Natalia E. Fernandez; Hinrich Staecker; Mei He

Journal: Science Translational Medicine

PubMed ID: 41223249

Doi: 10.1126/scitranslmed.adn3993

Variable PD-1 glycosylation modulates the activity of immune checkpoint inhibitors

Authors: Chih-Wei Chu, Tomislav Čaval, Frederico Alisson-Silva, Akshaya Tankasala, Christina Guerrier, Gregg Czerwieniec, Heinz Läubli, Flavio Schwarz

Journal: Life Sci Alliance

PubMed ID: 38176728

Doi: 10.26508/lsa.202302368

Products & Services: Mutant Libraries

An immunocytokine consisting of a TNFR2 agonist and TNFR2 scFv enhances the expansion of regulatory T cells through TNFR2 clustering

Authors: Masaki Inoue, Yuta Tsuji, Ayaka Kashiwada, Asahi Yokoyama, Akane Iwata, Yasuhiro Abe, Haruhiko Kamada, Shin-Ichi Tsunoda

Journal: Biochem Biophys Res Commun

PubMed ID: 38262291

Doi: 10.1016/j.bbrc.2024.149498

Products & Services: Gene Synthesis

Surface-modified measles vaccines encoding oligomeric, prefusion-stabilized SARS-CoV-2 spike glycoproteins boost neutralizing antibody responses to Omicron and historical variants, independent of measles seropositivity

Authors: Miguel Á Muñoz-Alía, Rebecca A Nace, Baskar Balakrishnan, Lianwen Zhang, Nandakumar Packiriswamy, Gagandeep Singh, Prajakta Warang, Ignacio Mena, Riya Narjari, Rianna Vandergaast, Kah-Whye Peng, Adolfo García-Sastre, Michael Schotsaert, Stephen J Russell

Journal: MBio

PubMed ID: 38193729

Doi: 10.1128/mbio.02928-23

Products & Services: Gene Synthesis