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A Physiologically Responsive Nanocomposite Hydrogel for Treatment of Head and Neck Squamous Cell Carcinoma via Proteolysis-Targeting Chimeras Enhanced Immunotherapy
Authors: Yaping Wu, Xiaowei Chang, Guizhu Yang, Li Chen, Qi Wu, Jiamin Gao, Ran Tian, Wenyun Mu, John Justin Gooding, Xin Chen, Shuyang Sun
Journal: Adv Mater
PubMed ID: 36656993
Doi: 10.1002/adma.202210787
Products & Services: Peptide Synthesis   
Functionalized biomimetic nanoparticles combining programmed death-1/programmed death-ligand 1 blockade with photothermal ablation for enhanced colorectal cancer immunotherapy.
Authors: Yuchen Xiao, Tianchuan Zhu, Qi Zeng, Qingqin Tan, Guanmin Jiang, Xi Huang
Journal: Acta Biomater
PubMed ID: 36442821
Doi: 10.1016/j.actbio.2022.11.043
SARS-CoV-2 Main Protease Targets Host Selenoproteins and Glutathione Biosynthesis for Knockdown via Proteolysis, Potentially Disrupting the Thioredoxin and Glutaredoxin Redox Cycles
Authors: Ignacio A Gallardo, Daniel A Todd, Stella T Lima, Jonathan R Chekan, Norman H Chiu, Ethan Will Taylor
Journal: Antioxidants (Basel)
PubMed ID: 36978807
Doi: 10.3390/antiox12030559
Phosphorylation of TRF2 promotes its interaction with TIN2 and regulates DNA damage response at telomeres
Authors: Radka Storchova, Matous Palek, Natalie Palkova, Pavel Veverka, Tomas Brom, Ctirad Hofr, Libor Macurek
Journal: Nucleic Acids Res
PubMed ID: 36651296
Doi: 10.1093/nar/gkac1269
Products & Services: Peptide Synthesis   
Chikungunya Virus and Its Envelope Protein E2 Induce Hyperalgesia in Mice: Inhibition by Anti-E2 Monoclonal Antibodies and by Targeting TRPV1
Authors: Carina Z Segato-Vendrameto, Camila Zanluca, Amanda Z Zucoloto, Tiago H Zaninelli, Mariana M Bertozzi, Telma Saraiva-Santos, Camila R Ferraz, Larissa Staurengo-Ferrari, Stephanie Badaro-Garcia, Marília F Manchope, Amanda M Dionisio, Felipe A Pinho-Ribeiro, Sergio M Borghi, Ana Luiza Pamplona Mosimann, Rubia Casagrande, Juliano Bordignon, Victor Fattori, Claudia N Duarte Dos Santos, Waldiceu A Verri
Journal: Cells
PubMed ID: 36831223
Doi: 10.3390/cells12040556
Products & Services: Codon Optimization   
How Many Sirtuin Genes Are Out There? Evolution of Sirtuin Genes in Vertebrates With a Description of a New Family Member
Authors: Juan C Opazo, Michael W Vandewege, Federico G Hoffmann, Kattina Zavala, Catalina Meléndez, Charlotte Luchsinger, Viviana A Cavieres, Luis Vargas-Chacoff, Francisco J Morera, Patricia V Burgos, Cheril Tapia-Rojas, Gonzalo A Mardones
Journal: Mol Biol Evol
PubMed ID: 36656997
Doi: 10.1093/molbev/msad014
Products & Services: Plasmid DNA Preparation   
Antagonism between Prdm16 and Smad4 specifies the trajectory and progression of pancreatic cancer
Authors: Eric Hurwitz, Parash Parajuli, Seval Ozkan, Celine Prunier, Thien Ly Nguyen, Deanna Campbell, Creighton Friend, Allyn Austin Bryan, Ting-Xuan Lu, Steven Christopher Smith, Mohammed Shawkat Razzaque, Keli Xu, Azeddine Atfi
Journal: J Cell Biol
PubMed ID: 36828547
Doi: 10.1083/jcb.202203036
Products & Services: Custom DNA/RNA Oligos   
FUNDC1 interacts with GPx4 to govern hepatic ferroptosis and fibrotic injury through a mitophagy-dependent manner
Authors: Yaguang Bi, Shuolin Liu, Xing Qin, Miyesaier Abudureyimu, Lu Wang, Rongjun Zou, Amir Ajoolabady, Wenjing Zhang, Hu Peng, Jun Ren, Yingmei Zhang
Journal: J Adv Res
PubMed ID: 36828120
Doi: 10.1016/j.jare.2023.02.012
Products & Services: Recombinant Proteins   
Revealing the role of tunable amino acid residues in elastin-like polypeptides (ELPs)-mediated biomimetic silicification
Authors: Yue Qiu , Yuanqing Lin , Bo Zeng , Peiliang Qin , Zhiwei Yi , Guangya Zhang
Journal: Int J Biol Macromol
PubMed ID: 36539170
Doi: 10.1016/j.ijbiomac.2022.12.152
Products & Services: Gene Synthesis   
Microenvironment-responsive anti-PD-L1 × CD3 bispecific T-cell engager for solid tumor immunotherapy
Authors: Dingkang Liu, Lichen Bao, Haichao Zhu, Yali Yue, Jing Tian, Xiangdong Gao, Jun Yin
Journal: Journal of controlled release
PubMed ID: 36669532
Doi: 10.1016/j.jconrel.2023.01.041
Products & Services: His Tag ELISA Detection Kit   

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