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Development of new mutant alleles and markers for and via CRISPR/Cas9-mediated mutagenesis to reduce trypsin inhibitor content and activity in soybean seeds

Authors: Zhibo Wang, Zachary Shea, Luciana Rosso, Chao Shang, Jianyong Li, Patrick Bewick, Qi Li, Bingyu Zhao, Bo Zhang

Journal: Front Plant Sci

PubMed ID: 37223818

Doi: 10.3389/fpls.2023.1111680

Products & Services: Protein and Antibody Isolation

Structural analysis of ING3 protein and histone H3 binding

Authors: Mariola Ferreras-Gutiérrez, Belén Chaves-Arquero, Amaia González-Magaña, Nekane Merino, Ignacio Amusategui-Mateu, Sonia Huecas, Francisco J Medrano, Francisco J Blanco

Journal: Int J Biol Macromol

PubMed ID: 37148949

Doi: 10.1016/j.ijbiomac.2023.124724

Products & Services: Protein and Antibody Isolation

A chemically inducible IL-2 receptor signaling complex allows for effective in vitro and in vivo selection of engineered CD4+ T cells

Authors: Peter J Cook, Su Jung Yang, Gene I Uenishi, Annaiz Grimm, Samuel E West, Li-Jie Wang, Chester Jacobs, Andrea Repele, Travis Drow, Ahmad Boukhris, Noelle P Dahl, Karen Sommer, Andrew M Scharenberg, David J Rawlings

Journal: Mol Ther

PubMed ID: 37147803

Doi: 10.1016/j.ymthe.2023.04.021

Products & Services: Protein and Antibody Isolation

Efficient expression of a cytokine combination in Saccharomyces cerevisiae for cultured meat production

Authors: Qingzi Lei, Jun Ma, Guocheng Du, Jingwen Zhou, Xin Guan

Journal: Food Research International

Doi: 10.1016/j.foodres.2023.113017

Products & Services: Protein and Antibody Isolation

Replisome dysfunction upon inducible TIMELESS degradation synergizes with ATR inhibition to trigger replication catastrophe

Authors: Jinal A Patel, Camryn Zezelic, Julie Rageul, Joanne Saldanha, Arafat Khan, Hyungjin Kim

Journal: Nucleic Acids Research

PubMed ID: 37144518

Doi: 10.1093/nar/gkad363

Products & Services: ORF cDNA Clones/MolecularCloud

Characterization of the conserved features of the NSE6 subunit of the Physcomitrium patens SMC5/6 complex

Authors: Edit Lelkes , Jitka Jemelková , Marcela Holá , Barbora Štefanovie , Peter Kolesár , Radka Vágnerová , Eva Dvořák Tomaštíková , Ales Pecinka , Karel J Angelis , Jan J Paleček

Journal: Plant J .

PubMed ID: 37191775

Doi: 10.1111/tpj.16282

Products & Services: Gene Synthesis

A cryo-EM structure of KTF1-bound polymerase V transcription elongation complex

Authors: Hong-Wei Zhang, Kun Huang, Zhan-Xi Gu, Xiao-Xian Wu, Jia-Wei Wang, Yu Zhang

Journal: Nat Commun .

PubMed ID: 37253723

Doi: 10.1038/s41467-023-38619-x

Products & Services: Protein and Antibody Isolation

13C Electron Nuclear Double Resonance Spectroscopy-Guided Molecular Dynamics Computations Reveal the Structure of the Enzyme–Substrate Complex of an Active, N-Linked Glycosylated Lipoxygenase

Authors: Ajay Sharma , Chris Whittington , Mohammed Jabed , S Gage Hill , Anastasiia Kostenko , Tao Yu , Pengfei Li , Peter E Doan , Brian M Hoffman , Adam R Offenbacher

Journal: Biochemistry .

PubMed ID: 37115010

Doi: 10.1021/acs.biochem.3c00119

Products & Services: Gene Synthesis

Li-Mg-Si bioceramics provide a dynamic immuno-modulatory and repair-supportive microenvironment for peripheral nerve regeneration

Authors: Yiting Sun , Hongjian Zhang, Yu Zhang , Zheqi Liu , Dongming He , Wanlin Xu 4, Siyi Li , Chenping Zhang , Zhen Zhang

Journal: Bioact Mater.

PubMed ID: 37292230

Doi: 10.1016/j.bioactmat.2023.05.013

Products & Services: Protein and Antibody Isolation

Optogenetic inhibition of Gα signalling alters and regulates circuit functionality and early circuit formation

Authors: Jayde Lockyer, Andrew Reading, Silvia Vicenzi, Caroline Delandre, Owen Marshall, Robert Gasperini, Lisa Foa, John Y Lin