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Detection of phosphorylation post-translational modifications along single peptides with nanopores

Authors: Ian C Nova, Justas Ritmejeris, Henry Brinkerhoff, Theo J R Koenig, Jens H Gundlach, Cees Dekker

Journal: Nat Biotechnol

PubMed ID: 37386295

Doi: 10.1038/s41587-023-01839-z

Products & Services: Peptide Synthesis

The full spectrum of OCT1 (SLC22A1) mutations bridges transporter biophysics to drug pharmacogenomics

Authors: Sook Wah Yee, Christian Macdonald, Darko Mitrovic, Xujia Zhou, Megan L Koleske, Jia Yang, Dina Buitrago Silva, Patrick Rockefeller Grimes, Donovan Trinidad, Swati S More, Linda Kachuri, John S Witte, Lucie Delemotte, Kathleen M Giacomini, Willow Coyote-Maestas

Journal: biorxiv

PubMed ID: 37333090

Doi: 10.1101/2023.06.06.543963

Products & Services: Custom DNA/RNA Oligos

Efficient production of fluorophore-labeled CC chemokines for biophysical studies using recombinant enterokinase and recombinant sortase

Authors: Wenyan Guan, Ning Zhang, Arjan Bains, Mourad Sadqi, Cynthia M Dupureur, Patricia J LiWang

Journal: Biopolymers

PubMed ID: 37341434

Doi: 10.1002/bip.23557

Products & Services: Molecular Biology Reagents

Rise of the RNA machines - self-amplification in mRNA vaccine design

Authors: Jerome D G Comes, Gorben P Pijlman, Tessy A H Hick

Journal: Trends Biotechnol

PubMed ID: 37328401

Doi: 10.1016/j.tibtech.2023.05.007

Products & Services: Peptide Synthesis

Electrochemical biosensor strategy combining DNA entropy-driven technology to activate CRISPR-Cas13a activity and triple-stranded nucleic acids to detect SARS-CoV-2 RdRp gene

Authors: Chenyi Zhuo, Zichun Song, Jiuying Cui, Yuanxun Gong, Qianli Tang, Kai Zhang, Xinlei Song, Xianjiu Liao

Journal: Mikrochim Acta

PubMed ID: 37351704

Doi: 10.1007/s00604-023-05848-2

Products & Services: Synthetic Guide RNA

Optimization of mammalian expression vector by cis-regulatory element combinations

Authors: Lu-Yu Zhou, Shuang Zhang, Li-Yun Li, Guo-Yu Yang, Lei Zeng

Journal: Mol Genet Genomics

PubMed ID: 37318628

Doi: 10.1007/s00438-023-02042-0

Products & Services: Gene Synthesis

miR‑124 inhibits cardiomyocyte apoptosis in myocardial ischaemia‑reperfusion injury by activating mitochondrial calcium uniporter regulator 1

Authors: Linlin Guo, Chaoying Liu, Chunyan Jiang, Yanhan Dong, Lynn Htet Htet Aung, Han Ding, Yanyan Gao

Journal: Mol Med Rep

PubMed ID: 37326122

Doi: 10.3892/mmr.2023.13031

Products & Services: Molecular Biology Reagents

Nullomer peptide increases immune cell infiltration and reduces tumor metabolism in triple negative breast cancer mouse model

Authors: Nilufar Ali, Cody Wolf, Swarna Kanchan, Shivakumar R Veerabhadraiah, Laura Bond, Matthew W Turner, Cheryl L Jorcyk, Greg Hampikian

Journal: Res Sq

PubMed ID: 37461536

Doi: 10.21203/rs.3.rs-3097552/v1

Products & Services: Peptide Synthesis

Lymphocyte infiltration and antitumoral effect promoted by cytotoxic inflammatory proteins formulated as self-assembling, protein-only nanoparticles

Authors: Carlos Martínez-Torró, Lorena Alba-Castellón, Luis Miguel Carrasco-Díaz, Naroa Serna, Laura Imedio, Alberto Gallardo, Isolda Casanova, Ugutz Unzueta, Esther Vázquez, Ramón Mangues, Antonio Villaverde

Journal: Biomed Pharmacother

PubMed ID: 37276641

Doi: 10.1016/j.biopha.2023.114976

Products & Services: Protein and Antibody Isolation

Phage anti-CBASS protein simultaneously sequesters cyclic trinucleotides and dinucleotides

Authors: Xueli Cao, Yu Xiao, Erin Huiting, Xujun Cao, Dong Li, Jie Ren, Linlin Guan, Yu Wang, Lingyin Li, Joseph Bondy-Denomy, Yue Feng

Journal: biorxiv

PubMed ID: 37398474

Doi: 10.1101/2023.06.01.543220

Products & Services: Protein and Antibody Isolation